Brain Protein "Rescues" Neurons From Atrophy
...and neurodegenerative diseases such as Parkinson'" disease and amyotrophic lateral sclerosis (ALS). The rese... diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Even if these diseases do not arise specifically from such defect...... Additional background: Insights into Parkinson's disease The research with the knockout mice could also pr...igra, slowly deteriorate and die.Thus, Parkinson's disease begins with small tremors and progresses to atotal inability to initiate movement. Currently incurab...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...al deterioration,such as that seen in Huntington's disease patients. Furthermore, their findings may answer...ewer than 30times, genes that produce Huntington's disease and other such brain disordersmight repeat the sequence between 40 and 100 times. As the repetition ...Tumor Suppressor Gene Located In Liver Cancer Cells
...ell as new treatments, the researchers said. The disease is often far advanced at detection, and the five-year survival rate in the United States is only 4 percent. A report on this tumor suppressor gene appears in the December issue of Nature Genetics. Along with principal investigator Randy Jirtle, Gera...Computer Program For Quicker, More Detailed Mapping
...The more detailed maps are essentialin identifying disease genes, especially for diseases that are inheritedin a complex manner and aren't due to a defect in a single gene," saidMyers....Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...dramatic and almost completereversal, all signs of disease completely disappeared. The findings support pre... if mutations in the gene correlatewith autoimmune disease in people. "The TTP-deficient mouse is an exciting new model of arthritis,"said Haynes, chairman ...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
...called activin receptorlike kinase 1 (ALK1) to the disease hereditary hemorrhagic telangiectasia(HHT), a blee...ngepisodes in affected people. In some people, the disease is only a cosmeticproblem with tiny red blotches forming on skin or recurring nose bleeds.Others suf......hort Northeastern growing seasons and exhibit some disease resistance. Growers were instrumental in both the...inifera parent. "It is much more winter hardy and disease resistant than GewŸrztraminer with a better balance of sugar, acid, and pH levels," said Reisch...Honeybees In The Wild Nearly Gone In North America
... were ever together before,we could expect to have disease outbreaks and other challengesoccur. We can't just whimsically switch to different bees andhave that solve all the problems."...Florida Researchers Discover Gene For Fatal Childhood Disease
... causes the disease, how it protectsagainst kidney disease in lupus, and how it makes people susceptible to cancer."...Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs
...ically, Sanjayan adds, "That doesn't bode well for disease resistance. If a new disease arises, either they'll all be resistant or they'll all be wiped out. You may not get a middle respon...Protein Glitch May Be Early Problem In Inherited Alzheimer's
... percent of all "early onset" familial Alzheimer's disease (FAD) cases, cases where symptoms first appear in patients in their late 20s to the their late 50s. Because presenilin is present only at very low levels, Sisodia notes, it's unlikely to be directly causing the widespread damage to nerve cells s...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...ce, perhaps when a transcriptionfactor is mutated, disease can result, the scientists say. "It is a parallel process to what is known as oxidative stress, inwhich an excess of oxygen in cells can lead to a host of diseases, as wellas the cumulative damage we call aging," Stamler said. "NO hasa simi...Genetic Alterations Linked To Cancer In Some Blood Samples
...al to alterations from the tumor itself. Examining disease outcomes, the researchers found that 4 out of the 6 patients with positive test results subsequently died of their cancer compared to only 3 of 15 with negative test results. Additionally, the three patients who developed distant metastases (dissemi...Low-Protein Diet May Reverse Kidney Disease
...th amino acid supplements may cure a severe kidney disease in some people, a Johns Hopkins study shows. The r...ur findings is that the common opinion that kidney disease patients shouldn't be given severely protein-restricted diets needs to be reconsidered." Hopkins res...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
...ce, perhaps when a transcriptionfactor is mutated, disease can result, the scientists say. "It is a parallel process to what is known as oxidative stress, inwhich an excess of oxygen in cells can lead to a host of diseases, as wellas the cumulative damage we call aging," Stamler said. "NO hasa simi...Duke Primate Center Sets October Expedition To Find 'Juliet'
...e capturedanimals are well fed, and protected from disease and natural enemies, theycan produce from five to 10 times more offspring that survive to adulthoodthan wild animals normally can." The outlook for diademed sifakas in the wild is especially grim, becauselogging operations in the Madagascar jungles ...Researchers Find Genetic Clues To Intestinal Disease
... Hopkins researchers have shown that an intestinal disease affecting 400,000 people in the United States is a...lthough earlier studies had suggested that Crohn's disease might be several distinct disorders, this is the first large study of a group of families that confi...Northwestern Scientists Discover How Herpes Simplex Virus Infects Cells
...talia, corneal destruction,encephalitis and severe disease of newborns. The virus can bind to manytypes of human cells but is capable of penetrating only certain cell types. Rebecca Montgomery, a research associate in Spear's laboratory, cloned ahuman gene that induces production of a protein that allows her......ere at higher risk of developing bladder cancer, a disease known to be associated with cigarette smoking. Components of cigarette smoke also have been shown to cause breast cancer in rodents. To investigate the possibility that slow-versus-fast acetylation could affect the incidence of breast cancer among ...