MIT Biologists Identify Aging Mechanism
...N. Mutations in WRN result in Werner's Syndrome, a disease whose symptomsresemble a fast-forward aging process. The MIT biologists demonstrated thatexperimental mutation of SGS1 -- the yeast homolog for WRN -- produced symptomsof aging in yeast cells. Again, the biologists noted how aged SGS1 yeast cells di...Mapping The Way To A Bigger Prawn
...ts such as those which influence flesh quality and disease resistance. This early success has resulted in a growing international interest in CSIROs activities in the area . CSIRO scientists are planning to collaborate with scientists with complementary skills from the Australian Institute of Marine Scie...Increased Amount Of Enzyme In Brain May Be Marker Of Alzheimer's Disease
...ents withAlzheimer's disease. Alzheimer's disease researcher M.-Marsel Mesulam, M.D., and colleagues... behavioraland cognitive neurology and Alzheimer's disease program at Northwestern. In this study, he and his colleagues tested brain tissue specimens...Researchers Discover New Genetic Risk For Alzheimer's Disease
...between two substances previouslyimplicated in the disease - APOE, a cholesterol-carrying protein, andbeta-am...The two groups studied individuals withAlzheimer's disease and compared them with individuals of the same age who didnot have Alzheimer's disease. In ...Peutz-Jeghers Disease Gene Identified: Enzyme Loss Causes Polyps And Cancer
...ghers syndrome. This rare autosomally inherited disease is characterized by gastrointestinal polyps, br...nce. A serious life-threatening feature of this disease are various tumors which can develop in the gastrointestinal tract, pancreas, ovaries, testis, br...Early Career Development Grants Foster Faculty Research And Education
...volution in a microorganism which initially causes disease should eventually allow it to assist rather than weaken its host - a relationship termed "symbiosis." The research, using fruit flies,may provide important insights into the reproductive success, behavior and genetic divergence of many organisms. B...Gene Therapy Trial Takes Aim At Deadly Brain Cancer
...igned to see if gene therapy can not only delay disease progression, but also provide patients with an improved quality of life. Neurosurgeon David Andrews, M.D., associate professor of neurosurgery, and his colleagues have already treated three patients, and are hoping to recruit several mo......antbreakthrough in studies of bacteria that cause disease in crops worldwide butwhose basic functions have e...ide response has been used asa tool for cloning of disease resistance genes from tomato, lettuce and rice,"said Carol Ishimaru, a lead researcher on the projec...Chlamydia Vaccine Developed At UMass
...se who have formulated a vaccine that prevents the disease chlamydia, the leading cause of female infertility...features, explains Stuart. Besides the form of the disease which causes female infertility, and which can be sexually transmitted, another form of chlamydia is...Genetics May Explain Why African Americans More At Risk For Strokes Caused By Bleeding In The Brain
... result, setting the stage foratherosclerosis, the disease process that can create the blood vesselobstruction that can trigger a heart attack or stroke. "We and others have observed that African Americans tend to be morelikely to have bleeding strokes and have a worse outcome," says Alberts. "Webe...Doublecortin : A Novel Gene Involved In Cortical Development
...ing the major role of theDoublecortin gene in this disease condition. Furthermore, the authors showed that Doublecortin was strongly expressed in thefetal brain, suggesting its implication in the early stages of corticaldevelopment. The discovery of this gene has two important implications. First, it advan......d accurately toidentify stresses (water shortages, disease and pests) and ultimately improveproductivity. As part of this work, algorithms that relate hyperspectral imagesof foliage to plant/crop stresses are being developed. The laboratory's extensive background in arms control nonproliferation detectionan...STS-89 Will Carry Five Science Payloads From NASA/Marshall
...y synctial virus (RSV),the most serious infectious disease that affects infants in the United States.More than 4 million cases a year are reported, with more than 4,000 infantsdying from it. The active region of the antibody has been defined, whichwill help scientists to develop smaller, more easily made mol...Cellular 'Short Circuit' Causes Insulin Resistance
...ment of the human condition. New ways of fighting disease and hunger, protecting the environment, and harnessing alternative sources of energy are high priorities. Weizmann Institute news releases are posted on the World Wide Web at http://www.weizmann.ac.il and also at http://www.eurekalert.org ....Family Ties To Sudden Cardiac Arrest; Study Finds Risk Goes Up 50 Percent
...est is not explained just by suchtraditional heart disease risk factors as diabetes, high blood pressure and ...riedlander. "This indicates thattraditional heart disease risk factors account for only a small part of theclustering and does not explain the familial patter...Detective Work Uncovers New Tick-Borne Disease In North Carolina And The Southeast
...en inpeople bitten by ticks infected with the Lyme disease bacteria. Of the 12,000 cases of suspected Lyme disease recorded by the CDC in1995, the majority, by far, came from northern states where the diseaseis carr...UF Researchers Identify Virus That May Cause Epidemic Disease In Sea Turtles
...Hospital have demonstrated clearly that thisdeadly disease is caused by an infectious agent," said PaulKlein,.... But it is a strong candidate for the causeof the disease because infection with it is closely associatedwith tumor development. "This is the first vi...Memorial Sloan-Kettering Investigators
...One such cancer might be non-Hodgkin's lymphoma, a disease that strikesfar more patients than APL: More than 50,000 people in the United States arediagnosed with non-Hodgkin's lymphoma each year. Mutations in a gene calledBCL-6 make up the most frequent genetic alteration in non-Hodgkin's lymphoma.Alteration...Transgenic Mice Created By Researchers May Shed Light On Human Heart Disease
... Known as hypertrophic cardiomyopathy, the genetic disease is markedby significant thickening of the heart mu...tmentwho is spearheading the research effort. The disease can obstruct bloodflow in heart ventricles, lessening their ability to pump blood into thearteries. ......y for the delta 32 mutationsignificantly slows HIV disease progression in children born to seropositivemother...ing the influence of delta 32heterozygosity on HIV disease progression in adults are that it is usuallydifficult to determine the precise date of infection and...