Genetically modified bacterium as remedy for intestinal diseases
...al medicine, Trefoil Factors, in the intestines of diseased mice. A typically Western disease Chronic intestinal inflammations, such as Crohn's disease, are occurring with increasing frequency, striking young adults in particular. In an advanced stage of such inflammations, patients can eat only via cathet...Growth hormone and IBD: Reduction of intestinal inflammation, promotion of growth
...elf is able to directly reduce inflammation in the diseased intestine, as well as promoting growth. In the long run, "this may lead to new therapeutic approaches which will take advantage of these properties in both improving growth and intestinal healing in IBD," Dr. Denson noted. Background and results S...NJIT professor receives Presidential Award for breakthrough research with adult stem cells
...physicians treat patients with severely damaged or diseased tissues."...Skin stem cells give hairless mice hair
...specialized cells that could regenerate damaged or diseased skin, brain, heart or other organs. The new findings constitute another step toward understanding how to mimic the chemical signals that the cells require to differentiate into mature tissues, according to Howard Hughes Medical Institute investigator...Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...reatment of myocardial infarction. By regenerating diseased myocardium and promoting cardiac repair, embryonic stem cells provide a unique therapeutic modality that has the potential to reduce the morbidity and mortality of this prevalent heart disease." Looking ahead, they noted that issues to be resolved i...New discovery may help transplants survive
... receive corneal transplants to replace injured or diseased corneas. Approximately 90 percent of corneal transplants are successful because the eye is intrinsically less likely to reject transplanted material than other parts of the body. However, to suppress rejection of corneal transplants, patients need to...New glycan arrays discover autoimmunogenic activities of SARS-CoV: concern over monkey vaccine
... physiology to the understanding the mechanisms of diseased and healthy states....Gene profiles could improve acute leukemia diagnosis and lead to better treatments
...amples of genetic material obtained from normal or diseased cells. HSCs are parent cells in the bone marrow that can potentially give rise to any one of the various types of blood cells. Progenitor cells are those that have arisen from HSC and are committed to producing a specific type of blood cell. The st...Macrophages, not stem cells, correct liver disease by fusion
...rtion among many scientists that stem cells repair diseased tissue by transforming into other cell types in a ...e marrow stem cells themselves, are what fuse with diseased liver cells, ultimately curing a genetic liver disease. "The most important discovery is you don't n...Newly grown kidneys can sustain life in rats
...Growing new organs to take the place of damaged or diseased ones is moving from science fiction to reality, according to researchers at Washington University School of Medicine in St. Louis. Scientists have previously shown that embryonic tissue transplants can be used to grow new kidneys inside rats. In thei...Umbilical cord blood transplants, bone marrow transplants save lives
...ion. The bone marrow transplant procedure replaces diseased or damaged stem cells of the patient with healthy stem cells from a tissue-matched donor or, in some cases, from the patient. "The blood that remains in the umbilical cord and placenta following birth is a rich source of stem cells from which new, h...Fox Chase discovery may help physicians diagnose, treat devastating childhood disease
...sease is early diagnosis and surgery to remove the diseased segment of the bowel. In general, the prognosis for most children after surgery is very good. However, a significant percentage of patients develop long-term complications or die of complications associated with the disease. "Currently, ten genes o...Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
...culture nanoparticles from filtered homogenates of diseased calcified human cardiovascular tissue. These cultu...niques. They point out that what is recovered from diseased calcified tissue replicates in culture, but that they have not yet been able to identify or label wh...... they isolated minuscule cell-like structures from diseased human arteries. These particles self-replicated in...ein unique to nanobacteria, they found it bound to diseased tissue, even when the calcium was washed away, but not to healthy tissue. On one sample of the self-...Regeneration of injured muscle from adult stem cells
... muscle cells, effectively replenishing injured or diseased muscle tissue, there's hope of reversing the debilitating effects of progressive muscle-wasting diseases. Though the usefulness of such an approach in humans will require intensive investigation, the results on these mouse adult stem cells are encour...Molecular mechanism found that may improve ability of stem cells to fight disease
...iety of diseases due to their ability to replenish diseased cells and tissue. While they are unique in this ability, it remains a challenge to effectively treat disease long-term with stem cells because of our inability to grow them in the laboratory. Defining the molecular switch in the stem cell replication...Genetic signature may predict recurrence in colon cancer patients
... Stage II, colon cancer surgical resection of the diseased tissue is considered highly effective, up to 20-30 percent of these patients can later develop recurrence and die from the disease. Patients classified as Dukes' B are thought to only have local disease, however, the incidence of relapse indicates e...Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study
...of the periodontitis patients had archaea in their diseased subgingival spaces, but nowhere else in their mouths. In addition, the relative abundance of archaea correlated with disease severity. Their findings are published in this week's issue of the Proceedings of the National Academy of Sciences. "Of cours...Pittsburgh NMR Center for Biomedical Research at Carnegie Mellon
...ethods to perform "virtual" pathologic analyses of diseased brain tissues with MRM. These analytical tools will unambiguously discriminate between nerve destruction caused by MS and other types of neurological injury that often appear indistinguishable using conventional MRI. Project scientists also will desi......oordination might be altered in cancerous or other diseased cells....