New analysis gives cancer patients personalized prognosis
...Nevins, Ph.D. "Therefore, every cancer has its own distinct properties. Our approach allows us to capture characteristic patterns underlying those different disease states and to utilize that information to make informed predictions about a patient's risk of recurrence that can then be applied to make the bes...Measurement clarifies role between protein structure and cell adhesion
...measurements show that NCAM binds in two spatially distinct configurations that result in different membrane s...odels as contributing to spatially and molecularly distinct NCAM bonds. "The different bonding configurations may serve as scaffolds that hold the membranes apa...Fat cell hormone causes weight loss
...fat hormones also control metabolism through other distinct pathways in the brain. "We focus on the brain because it is a major coordinator of feeding, metabolism, and hormones, including insulin," says Ahima. ...Insights on stroke from the peripheral blood suggest ways to develop markers and therapies
...imal studies in the late 1970s that there were two distinct zones of damage from ischemic stroke: an "infarct" zone of severely reduced blood flow, or ischemia, that could survive only minutes, and an "ischemic penumbra," tissue located at the edges of the infarct zone which could survive from three to six ho...New research explores 'early bird' and 'night owl' sleep patterns
...rch in inbred strains of mice has previously shown distinct variations in the pattern of slow wave sleep between some strains. This study investigated differences in circadian slow wave sleep and activity patterns in three inbred strains of rats previously used in sequencing the rat genome. If a difference i...Chicken litter harbors agents that generate antibiotic multi-resistance, according to UGA study
...or integrons that assemble these large clusters of distinct resistance genes? To find out, they collected samples of poultry litter from Georgia broiler houses regularly over a 13-week period. Litter begins as a bedding material of softwood shavings placed in commercial broiler houses before chicks are b...Rewriting textbooks on DNA crossover
...r and non-crossoverrecombination are distinct, and distinct from an early stage, Huntersaid. That turns the textbook account of meiosis on its head, hesaid. While researchers now have a better understanding of the process, howthe decision is made remains a mystery, Hunter said. "We're getti...Young chimpanzees show sex differences in learning
...o be published in the journal Nature April 15. The distinct sex differences in learning this skill are akin to differences between young girls and boys as they learn fine motor skills like writing, the researchers said. The authors said the study, which was done at Gombe National Park in Tanzania, has yielded...Sticklebacks reveal secrets to evolutionary change in Stanford study
...icklebacks, with their recent divergence into many distinct populations, present an opportunity to study recent limb evolution. The group looked at two populations of freshwater threespine sticklebacks that had lost their hind fins. Working with senior co-author Dolph Schulter of the University of British Col...Genetic screening study at Stanford ID's most aggressive adult leukemia strains
... each sample. From this, the researchers found two distinct patterns of which genes were turned on or off. These patterns correlated with how long the intermediate-risk patients lived after diagnosis. Those in the first group lived on average about twice as long as those in the second group. "You don't see a ...Keck Futures Initiative announces grant recipients
...y other cells. Each different stimulus triggers a distinct cellular response; yet cells use a limited number of component proteins to transmit these numerous signals. Bardwell will investigate how modular, adhesive protein-protein interactions and feedback circuits collaborate to provide specificity in such...Imaging the brain solving problems through insight
...olved quickly with or without insight, and evoke a distinct Aha! moment about half the time they're solved. Subjects pressed a button to indicate whether they had solved the problem using insight, which they had been told leads to an Aha! experience characterized by suddenness and obviousness. While several r...Researchers go fishing, pull out antigens
...taining fluorescent tags. When the receptors bound distinct MHC/protein complexes, the researchers isolated the insect cells displaying them. They then sequenced DNA in the baculovirus infecting the insect cells, and identified the protein fragments that the receptor bound. Thus, they could identify the spec...Researchers identify unifying code among diverse classes of natural antibiotics
...tructural signature that is conserved in otherwise distinct classes of antimicrobial peptides. Antimicrobial peptides are small, naturally occurring protein antibiotics that protect organisms including man - against infection. The discovery of such a broadly encompassing structural signature within these an...Oldest known evidence of cat taming found in Cyprus, researchers report in Science
...st to domesticate cats, breeding them to produce a distinct new species around 4,000 to 3,900 years ago. Although researchers have long suspected that humans began taming wild cats much earlier, they had limited evidence supporting this idea. Wild cats probably began to associate with humans as agricultural ...Scientists question reports of massive ant supercolonies in California and Europe
... been infested by numerous colonies of genetically distinct Argentine ants during the last 100 years. Challenging the supercolony paradigm is more than an academic exercise, says Stanford biologist Deborah M. Gordon. Argentine ants have had a major impact in many parts of the world, she says, and understand...Genetic trick adapted from viruses makes gene therapy vectors more versatile
... produced that automatically breaks into multiple, distinct proteins. St. Jude researchers used genetically modified mouse immune system cells called T lymphocytes to test the efficiency of this technique in making the CD3 complex, which is part of the T cell receptor, a large protein lodged in the cell's me...Leptin rewires the brain's feeding circuits
...the brain, leptin affects food intake by acting on distinct classes of neurons in the hypothalamus that express the leptin receptor. Leptin decreases feeding and fat deposition by acting on two classes of neurons. Leptin suppresses the activity of neuropeptide Y (NPY) neurons and it enhances the activity of p...NJIT chemists pave way for cheap, usable field test for polluted, toxic, water, air, food
...the targeted nanoparticles to form themselves into distinct micro channels. Scientists often refer to this hard gel process as a "sol-gen synthesis." This latter approach also involves a solid phase extraction in micro channels through which fluid flows on nanoparticles. Mitra's research interests i......tical and biotechnology industries have maintained distinct goals, activities, and capabilities. While academic cancer centers excel at basic research and clinical trials, the pharmaceutical and biotechnology companies possess enormous capability to identify and synthesize drugs. The new Dana-Farber center wi...