Immortalizing Enzyme Does Not Make Human Cells Cancerous
...merase, more than 90 percent of cancer cells,which divide indefinitely, do. "We clearly demonstrate that the expression of telomerase in culturedhuman cells does not cause cancer progression," said Wright, thereby reducingconcerns that telomerase might act as an oncogene, a gene that can induce a cell...Gap Widening Between Genetic And Behavioral Research
...arch. One of the worst consequences of the divide between biology andbehavioral sciences is a widesp...o-author Paul A. Scott, warns that this conceptual divide is widening asmolecular biologists discover genetic roles in more illnesses -- cancer,Alzheimer's, ...Adult Cells Undergo Identity Switch Reported In Science
...er. Embryonic stem cells are primordial cells that divide indefinitely andgive rise to the body's different cell types as they develop. However, althoughthese cells may have the potential to provide considerable benefits, they alsopose some controversial ethical implications because they come from humanembr...UF Researcher: New Techniques Help Reconstruct Ancient Diets
...rn ecological theory that animals who livetogether divide up the food supply in order to minimize competition for the sameresources, he said. "This is a milestone study," said John M. Rensberger, a professor in thedepartment of geological sciences and curator of vertebrate paleontology at theUnivers...Life Among Dead Brain Cells: Discovery Could Help Improve Memory Capacity Of Stroke Victims
... Regeneration is the ability of the stem cells to divide and produce newneurons. Plasticity is the ability... is the first to demonstrate that neural stemcells divide into neurons and astrocytes following ischemia. Though neurons arethe information cells in the brai...Abgenix Reports Encouraging Preclinical Results With ABX-EGF In Cancer Research
... whichincreases growth stimuli and causes cells to divide abnormally. Consequently,many cancer cells require EGFr for their survival. ABX-EGF binds with highaffinity to the EGFr and selectively targets these cancer cells by blocking thebinding of important tumor growth factors to the receptor. A key findi...Role Of Protein Linked To Colon Cancer Identified, Offering Potential Target For Therapy
...nown as retinoblastoma (Rb), coloncells proceed to divide uncontrollably and excessively, a hallmark of cancer. "We've known for several years that colon cancers have high levels of thisprotein, and that it almost certainly drives the cancer," said the senior authorof the study, Frank McCormick, Ph.D., F.R....Emory University Scientists Demonstrate New Pathway For Genetic Mutations In Everyday Cell Life
...e-related cell death in cells that do not normally divide -- likeneurons, for example, which could lead to neurodegenerative diseases." "This experiment was the 'proof of principle' that this kind of pathwaycould occur in live cells," explains Dr. Doetsch. "The extent to which thiswould occur for ...Genes Found That Label Cell Proteins For Disposal
...er, CDK4, controls a critical cellulardecision: to divide and grow or to arrest. Cyclin D has been found in a highpercentage of human head and neck cancers and breast cancers. "Whenover-expressed in mouse mammary glands, cyclin D causes breast cancer," Xiongsays. The UNC-CH discovery is the first to...... environment. Only robust cells in the limb budcan divide and form multiple limbs. This rigorous response to local infections,he says, may in fact suggest that the tadpoles are otherwise healthy.......etime. But likethe brain, the heart's cells do not divide and thus cannot repair damaged tissueafter an inju...ugs" to surrounding heart cells, so thatthey might divide and rejuvenate the damaged tissue. At the moment, gene therapy of this type remains only a potentia......om the energy in light. Thisability allows them to divide and multiply in a stable manner. NASA's "Life onthe Edge" project tests some of the limits to this remarkable behavior. Byclosing several green biomass mixtures into sealed jars, these organisms arefrozen within a deep freezer to a frigid -80 deg C (...UT Southwestern Researchers Find Way To Control Gene Activity, Opening Way For Cancer Drugs
.... It is switched on intumor cells allowing them to divide uncontrollably and be immortal. The same investigators published a related paper describing the rules forattacking DNA targets with PNAs. That study appeared in March in the Journal ofthe American Chemical Society. "A challenge that researchers have ...New Way To Modify Mammalian Genes: Honolulu Transgenesis
... organisminto the egg of another. The egg can then divide so that every cell in the newindividual contains the introduced DNA. The experiments demonstrated the newmethod using DNA for jellyfish green fluorescent protein to make green mice, andare reported in the May 14 issue of the journal, Science. The tea...A new view of visual system development
...atcontradicts current theories on how the two eyes divide up their "territories"in the visual cortex, ending up with equal shares. "The old theory is that inputs from the two eyes start out completelyoverlapping," explains Katz, "and they fight it out and separate into twoindependent territories with no fa...Transformation of normal human cells into cancer cells
...ase gene isswitched on, cells continue to grow and divide indefinitely. Such rampant,unchecked cell growth is characteristic of cancer, says Dr. Hahn, who is also anoncologist at the Dana-Farber Cancer Institute. Interestingly, in humans, thetelomerase gene is turned off in most normal cells and is turned...Enzyme discovery may link underlying processes in cancer and heart disease
...nt growth signalinside cells, instructing cells to divide more rapidly. Abnormal cell divisionor growth is seen in cancerous cells as well as in some forms of cardiovasculardisease. In the case of cancer, rapid and uncontrolled cell division leads to tumorformation. In cardiovascular disease, abnormal cel...Learning how organs tell left from right
...nces, the human bodyis symmetrical. If one were to divide the body into two halves, for example,each side would have a single arm and leg. But a look inside at the internalorgans shows that there is not perfect symmetry throughout the body. The heartand spleen normally reside on the left side and the liver ......ice. These results not only reveal anevolutionary divide between dicots and monocots but also caution scientistshoping to exploit Arabidopsis sequence for understanding cereal crops like riceand wheat. When it comes to gene sequence, there may be no substitute for thereal thing.......onary tree for their sample. Mitochondrial studies divide the western, central, and eastern chimps into discrete groups. By contrast, the Xq13.3 sequence tree showed that the geographical subspecies were in fact highly intermixed. Why would one type of DNA paint a picture of strict barriers erected between ...