Study: breath test effective in showing patients who should get less cancer drug
...o determine how fast their livers cleared the drug docetaxel and compared those results with results from a mea... uses the same enzyme system, or pathway, to clear docetaxel as it does to process erythromycin. "We didn't look at the data until the study was over," the phy...Study detailing safety and efficacy of exisulind in treating recurrent prostate cancer
...ynergistic effects between exisulind (Aptosyn) and docetaxel (Taxotere) in a variety of tumor types, Cell Pathways is planning to conduct a Phase III study of the Aptosyn/Taxotere combination in hormone-refractory prostate cancer patients. Clinical success in late-stage disease may benefit men who are in great...Cell Pathways CP461 demonstrates multiple anti-cancer activities
...comparing the activity of CP461 alone with that of docetaxel in rats implanted with human A459 non-small cell l...for 10 weeks, 2.5 mg/kg of once-weekly intravenous docetaxel for six consecutive weeks, or placebo. Mean survival times for rats receiving CP461 monotherapy at ...New study expands look at high-dose vitamin D with docetaxel for advanced prostate cancer patients
...tamin D in combination with the chemotherapy agent docetaxel (Taxotere), for patients with advanced prostate ca...ination with docetaxel, is any more effective than docetaxel alone for patients with androgen-independent prostate cancer (AIPC), an advanced form of prostate ca...Gene test could reduce unnecessary treatment for women with breast cancer
...r or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal treatment after surgery for breast cancer is crucial in reducing mortality. Patients react differently to chemotherapy drugs a...ECCO 12 - the European Cancer Conference
...of Peter Ravdin: First head-to-head paclixtaxel v docetaxel trial in breast cancer world-first presentation of findings Lynn Faulds-Wood & Kathy Redmond launch of the European Cancer Patient Coalition (ECPC) Europe's first patient advocacy group for all types of cancer Wednesday 24 September 13.00hrs ...Taxanes may enhance immunity in breast cancer patients
... study, taxanes drugs like paclitaxel (Taxol) and docetaxel (Taxotere) emerged as popular options for women whose disease had spread to their lymph nodes. "These findings are important because they suggest taxanes may enhance a woman's ability to respond to infection or even to fend off a possible recurrenc...Other highlights in the May 19 JNCI
... II clinical trials to evaluate the combination of docetaxel and trastuzumab with either of two platinum salts,... HER2. Both combinations had a similar toxicity to docetaxel plus platinum salts alone, and there was a low incidence of cardiac dysfunction. In addition, overal...When combining new oral anti-cancer agents with standard chemotherapy, timing may be crucial
...d erlotinib alone, the standard chemotherapy agent docetaxel alone, the two drugs simultaneously, and the two d... cell lung cancer cells. "We predicted that giving docetaxel first, then erlotinib, would be more effective than giving the erlotinib first, giving both drugs si...Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
...e they were treated with paclitaxel (Taxol) and/or docetaxel (Taxotere). Based on analysis to date, results showed a 15 percent (95% CI: 8-22%) overall response rate in 106 patients who received Abraxane 100 mg/m2 administered weekly over 30 minutes a day without premedication for three weeks followed by one w...