Experimental Therapy Makes HIV-Infected Cells Commit Suicide
...in the hinge of the scissors, preventing them from doing their job. But mutations in the protease can make the drugs ineffective. The drugs also inhibit a patient's own proteases, so they often are toxic. Riding his bike to work one day, Dowdy thought, "Why not use the viral protease to kill the...Estuaries Vital To The Productivity Of Southeastern U.S. Fisheries
...h," he said. "Losing seagrass or salt marsh is not doing the job, nor islosing mangroves." Scientists have gathered increasing evidence that estuaries like theChesapeake Bay and North Carolina's Pamlico and Albemarle sounds are beingdegraded by nitrogen from agricultural operations, lawn fertilizers and ...UF Researcher: New Techniques Help Reconstruct Ancient Diets
...zed horse teeth tosee what the animals ate, and in doing so reconstructed Florida's environment asit existed 5 million years ago. MacFadden's article in this week's issue of the journal Sciencedescribes how he analyzed ratios of carbon isotopes along with the scratches andpits in the fossilized tee......pointing, the underlying molecular interaction. In doing so, they sought to determine whether the extra-cellular portion of CD4,in the form of soluble CD4, was itself sufficient to represent the CD4-positivecell in these culture experiments. The answer was yes, determined bysubstituting a recombinant prot...Radioactive Beads Latest Weapon In Fighting Cancer In Dogs, Cats
...e for recovery. It's much harder on the animalthan doing the implant therapy." Chun said not all tumors can receive the implant, but that it is a goodtreatment option for a lot of different tumors. "It seems to be as successful as more conventional forms of therapy," Chun said."But we need two or three yea...Human/Insect/Jellyfish Genes Team To Quiet "Hyper" Nerve Cells
...ng the system. We'dnever be so bold to think about doing gene therapy for problems like this if wecouldn't fine-tune what we were doing and reverse it." The Hopkins group also developed a novel way to tell if the genes inthe......ys. "Using tools of just five years ago, a lab was doing well tocomplete 250 genotypings aweek; PROGRESS has boosted that weekly rate to 15,000." The researchers have been aggressive in recruiting families for the study. Manyof the families became involved after seeing an appearance on CNN's "Larry KingLiv..."Self Organizing Maps" Help Analyze Thousands Of Genes
...ifferent things, you might have 25 groups of genes doing similar things." Tamayo compares the final product of the SOM to an executive summary for CEOs. Rather than having to read every page of a 1,000-page report, CEOs can get anoverview of the report by simply reading the summary. "It's impossible tovis...A Bacterium Can Help Slow Global Warming
A BACTERIUM that digests methane is doing its bit to slow global warming, saythe American, German and Russian researchers who discovered it. But they warnthat the bacterium-the first of its kind to be found in acidic wetlands-is beingpoisoned by industrial pollutants. "The bacterium ...Structure Of Fat-Depleting Protein Reveals Important Functional Clues
...er proteins, known asantigenic peptides, and in so doing trigger an immune response to invadingmicroorganisms and viruses. Yet despite ZAG's similarity to MHC proteins, itapparently does not have a role in the immune system, Bjorkman said. Last year, however, researchers at Aston University in Birmingham,...Blue-Green Algae Has Dual Cholesterol Lowering Abilities
...benefits. He cautions, however, "we arecurrently doing studies to determine if the effects of AFA on cholesterol inratswill translate to humans." Drapeau collaborated with researchers at Massachusetts General Hospital, whichis affiliated with Harvard Medical School....Studies Document Ease Of Ecosystem Disruption
...aid Eric Berlow, arecent OSU doctoral graduate now doing research at the University of California,Berkeley. Underlying that approach is the assumption that by maintainingpopulations of the species believed to be the most important, the largerecosystem will be protected and the lesser species can be...Alzheimer's Disease And Developmental Biology Linked Through Single Molecule
... "We now see a common theme to what presenilin is doing in developmentand in Alzheimer's disease," Fortini says. "Presenilin is required for theprocessing, cutting, and function of critical proteins in both areas, anddefects in presenilin can lead to developmental problems in the one case and toneurologic...Plants Use 'Snorkels' To Survive Floods
...f this gas on the cell membrane play a role in its doing so. Various hormones evidently give the alarm to various parts of the plant so that the cells can react by accelerating their longitudinal growth and producing the life-saving shoots. Differences in the capacity to adapt to flooding have a major i...Melatonin Shapes Brain Structure In Songbirds
... we had started out trying to see whatmelatonin is doing in humans. Now, with this discovery, we can feed back theinformation to other scientists and, perhaps, help them understand what ishappening in other species." The next step, the scientists say, is to find out just how melatonin andtestosterone inter...How Can You Tell Whether Corn Is Fungus-Ridden?
...hat's exactly what researchers in Illinois propose doing to weedout kernels of corn that could end up poisoning your breakfast. Grain storesoften become infected with fungi that produce harmful toxins, and the foodindustry has to prevent such poisons ending up in cornflakes or animal feed. Current......ks and attempts to breakdown the beryllium, but in doing so causeslung scarring, known as granulomas. The scarring causes the lungs to stiffen,making it difficult to take a deep breath and interfering with the transfer ofoxygen from the lungs to the blood stream. For more information about berylliu......e growth factors criticalto healing, so we've been doing immunohistochemistry to look at what growthfactors really are present. That process is continuing."...Fishermen Are Killing Brown Pelicans With Kindness
...ath. "People that feed pelicans feel like they are doing something nice bygiving them a meal," Bresee said. "But by feeding them, they are killingthem with kindness." That theme appears on the educational signs Bresee and other marine agentsare posting at about 1,000 marinas statewide. The signs, produced ...Sandia, University Of Montana Researchers Try Training Bees To Find Buried Landmines
...arged bodies and bring samples back to thehive. In doing so they provide a chemical survey of an areaextending a mile or more from the hive in all directions. "Bees are like flying dust mops," says Bromenshenk."Wherever they go, they pick up dust, airborne chemicals,and other samples. If it's out there, th...