Molecular structure could advance understanding of human disorders
...been seen. Our structure shows the arm holding the door open for the copper to be deposited into the active site on the target protein." Metallochaperones are essential for the proper functioning of cells. They deliver heavy metal ions, such as copper and iron, to enzymes that need them to catalyze vital ...Plant diseases plague world trade
...hile under-regulation in some areas has opened the door for the potential spread of emerging diseases. There is enough concern that the worlds largest organization of plant health scientists plans to discuss these issues at their annual meeting in August. States George Abawi, a plant pathologist at Corne...Clemson-led team makes breakthrough in controlling Bt resistance in pests
... pests," Gahan said. "This discovery will open the door for other researchers and monitoring governmental agencies to assess resistance mechanisms and management strategies in insect pests. It will help us keep a handle on the development of insect resistance to Bt-genetically modified plants." Gahan cam...Blocking 'engulfment' gives dying cells new lease on life
... a few cells (5%) proceeded all the way to death's door but at the very last stage before death (stage 3 of 4), they reverted to a normal appearance and survived. Second, the researchers found that blocking engulfment in animals with a genetically weakened cell death signal increased the number of cells ...Research team unlocks secrets of the firefly flash
...as discovered in a strategic location - right next door to the light-generating apparatus in the photocytes. Taken all together, these findings suggest how the flash control machinery may work. Normally, the firefly's lantern is turned off and the photocytes are dark. Oxygen moving into the photocytes i...Researchers uncover a protein defect that causes a milder form of cystic fibrosis
...d no chloride can be transported. "This opens the door for new avenues of research in terms of rational drug design," added Dr. Deber. "We will look for molecules that could possibly break up the abnormal bond that is causing the protein strands to stick together." CFTR is a membrane protein with a mass...Blood vessels found to signal chain of destruction in bone diseases
...overed a mechanism in blood vessels that opens the door for bone loss in such diseases as rheumatoid arthritis, periodontal disease, osteoporosis, tumor-associated bone loss, or artificial implant loosening. Patricia Collin-Osdoby, Ph.D., research associate professor of biology inArts & Sciences at W......ady developed a robotic device that crawls under a door and detects chemicals. [Contact: Venu Varma] ENVIRONMENT The mercury mystery . . . Thousands of landfills around the nation may be serving as bioreactors, turning inorganic mercury into methylated or organic mercury, according to a study by re...Study reveals molecular key to tumor suppressor activity
...erstand exactly how the phosphate signal shuts the door on p53 export," Xiong said. "That knowledge can be used to develop a targeted treatment for malignant tumors."...Technology patented to create Pierces disease-resistant grapevines
...ically modified plants is that they could open the door to growing more valuable wine- and table-grape varieties in the Southeast and Florida, he added. Pierces disease is caused by a species of bacterium that lives exclusively in the water vessels of a variety of plants. The strain that lives in grape...In gene therapy first, scientists restore vision to dogs born blind
...shed in the May issue of Nature Genetics, open the door to developing treatment in coming years for people with a rare, inherited eye disorder. The scientists reported their success in three dogs with a condition closely resembling Leber congenital amaurosis, or LCA, a blinding disease caused by mutation......tus and sapiens, out-of-Africa proponents slam the door on interbreeding. Recent studies have only added fuel to the debate. For example, evidence from the three Neanderthals whose DNA has been analysed so far indicates that genetically there is more in common between us and them than there is between......lly the case. This sort of research might open the door to novel therapy for lung cancer. Dr. Mark R. Green, the Gilbreth professor of clinical oncology at the Medical University of South Carolina, said if the association between the protein and drug resistance proves to be a widespread phenomenon, it ...Novel compound inhibits HIV replication in cell cultures, suggesting possible new type of AIDS drug
...y a very powerful therapy because it may close the door to the virus," said Dr. Douglas, the chief of Immunology at Childrens Hospital and lead author of the article. CP-96,345 interrupts the process by which particular strains of HIV, the R5 strains, enter macrophages through receptors on the macrophages...Genomics portends the next revolution in agriculture
...duction. We need new models, but we can't shut the door on a technology that has tremendous potential to improve the lives of so many."...Plants as plants: gene could convert crops to plastics factories
...ials in their cells a discovery that may open the door to producing new types of plastics from plant materials. Clint Chapple, professor of biochemistry at Purdue University, and Knut Meyer of DuPont and Co., have cloned a gene from the common laboratory plant Arabadopsis that will allow materials to pro...Genetic basis of Alexander disease discovered
..., but are not sure why. "This is going to open the door to understanding how astrocytes respond to disease or injury," he said. Identifying the genetic cause gives researchers a starting point, but possible treatments are likely well in the future, Messing said. "I think parents who have had children with...New research software to simulate biochemical processes
...s in order to use one. This software will open the door to thousands of new research possibilities that will greatly expand our knowledge of the cellular process. According to Bruno Sobral, director of VBI, "the future of biology is intimately tied to computational modeling and simulation. This project wi...Screensavers of the world, unite!
...f thousands of nonscientists in research opens the door to new means of science education and outreach, in which the public becomes an active participant,`` the authors conclude. ``Part of our mission is to educate people,`` says Pande, so when volunteers check his Folding@home website, they are pro...Laser surgery halts chest pain over the long-term; scientists also looking into non-surgical TMR
..., another study being presented today may open the door to a non-surgical form of the laser procedure. TMR uses a carbon dioxide laser to make multiple channels in the heart for blood to flow through. Although no one is sure exactly why or how the procedure helps to reduce chest pain, it has proven to ...