Tag: "dose" at biology news

Vitamin C levels linked to amount of lead in blood

...ir diets, Simon says a multiple vitamin or amodest dose vitamin C supplement may be taken as an 'insurance policy.' The Recommended Daily Allowance (RDA) of vitamin C for non-smoking adults is 60mg and 100 mg for smokers. The RDA for children is 45 mg. However, new dietaryreference intakes for vitamin C...

Rockefeller researchers inject cells, boost immune system in humans

...nt provides the first conclusive evidence that one dose ofthese cells, called dendritic cells, can prompt a strong immune response, and itsuggests new ways of improving vaccines and protecting against cancer. "We've shown for the first time that a single injection of mature dendriticcells can induce a sig...

Blocking VEGF can enhance radiation therapy

...ple, giving mice with Lewis lung carcinoma a small dose of anti-VEGFreduced tumor size by 42.6 percent. Treatment with low doses of radiation alonereduced tumor size by 43 percent. But treatment with low doses of anti-VEGF andradiation resulted in reduction of tumor size by 78 percent. Combined treatment ...

Clinical results with AVANT rotavirus vaccine demonstrate nearly 90% protection in young children

...rease only in mild,transient fever after the first dose (19% vs. 5%) and no significant increase ingastrointestinal symptoms. AVANT has licensed the oral rotavirus vaccine to SmithKline Beecham (NYSE: SBH)for subsequent development and commercialization. "The rotavirus vaccineprovides a significant oppor...

Scientists clear hurdle in effort to destroy experimental brain cancers with viruses

...ntiviral mechanism. Chiocca's group found that one dose of cyclophosphamide inhibited IgMand complement function and allowed for increased survival of the virus in the tumors. The drug also lowered antiviral activity inhuman plasma samples. Though Chiocca cannot predict whether these results could hold up...

A few gut parasites could do you the world of good

... intocomplete remission," says Weinstock. A single dose of worms eased symptoms forabout a month. Inflammatory bowel disease-an umbrella term for ulcerative colitis andCrohn's disease-appears to be caused by an overactive immune system. Symptomsinclude diarrhoea, abdominal pain, bowel obstruction ...

Microbial janitors tackle nuclear clean-up problems

...s and cellulosewith a blender, and spice it with a dose of elemental sulfur. The end result isa vibrantly yellow gel with the consistency of the lemon curd you spread on atea-time scone. The sulfur not only feeds the microbes, the bright color makesthe gel easy to see, a plus when applying it to a surfa...

Genetic variation in sensitivity to estrogen may mask endocrine disruption

... suppression of testis weight even at the lowest dose of estradiol. C17and S15 mice were almost as sensi... considered when determining the appropriate dose of hormones used in contraceptives, hormone replacementtherapy, and prevention and treatment of ...

University of Maryland study links vitamin B deficiency to risk of stroke in younger women

...signed to takemultivitamins with or without a high dose of B vitamins. Until the answers are in, Dr. Kittner recommends that people get theirfolic acid and B vitamins from eating a balanced, healthy diet that includesseven servings of vegetables and fruit each day, along with moderate consumption...

Fish-oil supplement slows progression of kidney disease

ROCHESTER, MINN. -- A daily dose of fish oil slows the progression of disease inpeople suffering from IgA nephropathy, a relatively common kidney disease withpotentially serious consequences. An earlier Mayo Clinic-led study showed that,after two years, people who took the fish oil ...

New hope for self-injury sufferers

...curs, for example,when a heroin addict takes a low dose of heroin. Thompson and his colleagues have also discovered the locations on the body wherepeople self-injure is indicative of whether naltrexone will reduce self-injury. People who self-injure in acupuncture analgesia sites, such as the temple or th...

Researchers find two metabolites of gasoline additives in humans

...e using these data to develop a model to study the dose effectsfor MTBE in humans. Understanding the relationship between MTBE effects inrodents and humans is essential for evaluating potential human health riskbased on rodent bioassay data. The findings appear in the September 20th issue of Chemical Rese...

Eating soy can lead to dramatic declines in cholesterol, Wake Forest study shows

...es not lowercholesterol, nor does a relatively low dose of isoflavones in soy protein, saidJohn R. Crouse,... When all patients who got the 62 milligrams dose were consolidated (including those whose LDL was closer to normal), LDL cholesterol still droppedby ...

CIIT publishes formaldehyde cancer risk assessment

... formaldehyde, including site-specific modeling of dose of formaldehyde delivered to the upper respiratory tracts of animals and humans. An important feature of this assessment is the use of a two-stage clonal growth model of carcinogenesis that incorporates data on the rate of cell division and on the nu...

Novel anti-cancer agent shows minimal side effects with preliminary evidence of tumor shrinkage

...ion of the mucous membranes, which occurred at all dose levels studied, but did not increase in intensity ... researchers, ongoing studies are evaluating other dose levels and longer treatment duration to confirm safety and efficacy of CCI-779 before advancing to P...

Genetic information of world's most radiation-resistant organism decoded

... survive 1.5 million rads of gamma irradiation - a dose 3,000 times the amount that would kill a human. This dose of radiation shreds the bacteria's genome into hundreds of pieces. The organism's remarkable abilit...

Abgenix reports positive clinical data with ABX-IL8 in Psoriasis

...ed that ABX-IL8 was safe and well tolerated at all dose levels tested and that a dose-dependent improvemen...nd PGA measures and plaque photographs also showed dose dependent improvement. "The Phase I/II trial of ABX-IL8 was primarily designed to demonstrate saf...

Common cholesterol drugs could be used to treat osteoporosis, as reported in the 3 December issue of Science

...ull after only five days of treatment. In the oral dose groups, the statins caused increases in new trabecular bone (the type of bone found at the ends of bones like the femur) ranging from 39 to 94 percent after approximately one month's treatment. "It was totally amazing to us," Mundy said of the amount...

Abgenix initiates phase III clinical trial of graft versus host disease therapy

...e the 180-day survival rate observed in the lowest dose cohort, according to results presented at the annu...). Survival at 180 days for patients in the higher dose cohorts was 50% versus 22% in the lowest (presumed no effect) dose cohort. "ABX-CBL demonstrated ...

Study finds no evidence hormone benefits autism

...rolina researchers found no evidence that a single dose of the synthetic human hormone secretin benefited children with autism, an often severe developmental disorder. In a well-controlled study of 60 children, half of whom received synthetic secretin and half of whom received an inactive salt solution...

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