Tag: "dose" at biology news
Marimastat produces comparable survival rates to chemotherapy in some advanced pancreatic cancer patients
...ncer was 20 percent for patients given the highest dose
of marimastat and 19 percent for patients treated with gemcitabine. Although patients taking gemcitabine reported greater improvements in pain and mood, fewer toxic side effects (e.g., pulmonary complications and nausea) were reported in patients ta...
Ketek receives marketing approval in Europe
...opean Union (EU)-Member States. Ketek (800 mg oral dose
once daily) has been approved for the treatment of patients 18 years and older for community-acquired pneumonia (CAP), mild or moderate; acute exacerbation of chronic bronchitis (AECB); acute sinusitis; and tonsillitis/pharyngitis caused by Group A b...
FDA approves Abbott's Biaxin XL (clarithromycin extended-release tablet)for community-acquired pneumonia
...visit, which occurred 14 to 21 days after the last dose
was taken. According to study results, a clinica...n and clarithromycin are taken concomitantly. The dose
of clarithromycin should be halved or the dosing interval doubled in patients with severe renal impa...
Component of fly saliva makes promising Leishmaniasis vaccine
...st a serious parasitic infection have discovered a dose
of fly saliva might be just what the doctor ordered. Leishmaniasis, a disabling and sometimes deadly tropical illness, is caused by a parasite transmitted to people through the bite of a sand fly. In a report released today, scientists from the Nat...
Study detailing safety and efficacy of exisulind in treating recurrent prostate cancer
...occurred early in therapy and were reversible upon dose
reduction. Adverse biliary events occurred in two patients receiving exisulind; both patients had evidence of underlying gallstone disease. The authors report that few patients experienced adverse events that demonstrated a possible or probable rela...
UCSF study finds two old drugs may help fight prion diseases
... more readily and therefore could provide a higher dose
of the drug in the brain. The mouse cells used in the study were neuroblastoma cells, cancer cells that, by definition, multiply perpetually. These cells have been the basis of some prion studies for more than a decade, because they are susceptible ...
Research highlights from Pacific Northwest National Laboratory
...ng data to determine if radiation delivered at low dose
rates is equally responsible for causing cancer and other adverse health effects as the same doses delivered at high rates. PNNL scientists are working with other national and international institutions to evaluate radiation exposures in communities ...
Ecstasy component may help researchers measure brain damage from the drug
...r men who each volunteered to take a 100-milligram dose
of Ecstasy and submit blood and urine samples regularly for the following 24 hours. All were described as regular users of the drug. The researchers found nearly identical concentrations of HHMA and MDMA in the samples, establishing HHMA as a likely ...
Alcohol, women and pregnancy
...s monkey infants whose mothers consumed a moderate dose
of alcohol either continuously or during the human equivalent of the first or last two trimesters of pregnancy. (Moderate drinking in humans is defined as 7 to 14 drinks per week, or 1 to 2 drinks per day.) Schneider explained that not only do prim...
Catnip repels mosquitoes more effectively than DEET
...mained on the side of the tube treated with a high dose
(1.0 percent) of the oil. In the low-dose test (0.1 percent) with nepetalactone, an average of 25 percent five mosquitoes stayed on the treated side. The same tests with DEET (diethyl-m-toluamide) resulted in approximately 40 percent to 45 percent...
Studies offer data on potential impact of Reminyl on caregiver 'burden' in Alzheimer's disease
... receive placebo, 279 took a maximum daily Reminyl dose
of 16 mg and 273 received a maximum of 24 mg of Re...eeks, then increase to the recommended maintenance dose
of 16 mg per day. Physicians have the flexibility to increase the daily dose
to 24 mg after an addi...
Parasite offers natural way to control leaf-eating slugs
...an acre, costs about $50. One dose
of metaldehyde for the same size area costs about $10, Grewal said, but several doses have to be applied over the course of one growing season....
APS August/September journal hot picks
...and rhinitis alone is the fact that a much greater dose
of allergen is necessary to cause significant bronchoconstriction in allergy sufferers. This may explain why some individuals with allergies develop asthma symptoms on natural exposure to allergen, whereas others do not. But does allergen exposure p...
NHLBI supported study finds inhaled steroids accelerate bone loss in women with asthma -- treatment still recommended for persistent asthma
...f the inhaled steroids was directly related to the dose
-- that is, the bone density loss increased with t...nhaled steroid use on bone density was shown to be dose
related," notes Lenfant. "We encourage all patients with asthma to work with their doctors on a comp...
Soy protein prevents skin tumors from developing in mice, UC Berkeley researchers find
...s, the group that had received the highest lunasin dose
of 125 micrograms twice a week had a 70 percent lo...ce of tumors than the control group. "In the high dose
group, some mice did develop some tumors, but there were fewer tumors per mouse and there was a two-...
New DNA-base vaccine approach protects mice against anthrax
...ted with five times the lethal dose
of the anthrax bacterial toxin. All mice that had received the plasmid injections were immune while all animals in the control group died within several hours. Galloway says that the result...
Vitamin E and aspirin delay heart disease in mice even with high cholesterol levels
...that if you combine an antioxidant with even a low dose
of aspirin, you might be able to obtain primary pr...ase. The first test group was administered a daily dose
of Vitamin E that would have equaled 800 units in human subjects. "We found that Vitamin E reduced o...
Estrogen may protect against cocaine-induced brain dysfunction
...d female occasional cocaine users. An intravenous dose
of cocaine (0.4 mg/kg) was administered to nine men and 13 women. Men were studied once while women were examined during different phases of their menstrual cycle phases (days 3-8, follicular phase and 18-24, leutial phase) after the beginning of me...
Estrogen doesnt prevent second strokes: protective effects of hormone replacement therapy challenged
...gen (estradiol 17-beta at the standard replacement dose
of 1 mg daily) or a matching placebo. Patients were studied for an average of 2.8 years. They stopped receiving the estrogen or placebo if they had a stroke. The researchers found that there was no significant difference in the incidence of strok...
ChemGenex uses genomics approach to develop new anticancer drug, predict possible side effects
...ial designers predict the most effective doses and dose
scheduling, as well as provide key insights into d...the pattern of gene expression in relation to drug dose
and schedule of administration, we can also predict potential toxicities and identify targets to imp...
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