National award recognizes local researcher Andrew Hamilton
...ring the stuckswitch. Some of these molecules have dramatically slowed the growth of humantumors in mouse models and are moving toward clinical trials in humans. Hamilton says he was never a chemistry-set kid. "I was sports-mad growing up. Itwasn't until much, much later that I came to appreciate chemistry. I thi...Genetic variation in sensitivity to estrogen may mask endocrine disruption
...etically different strains of laboratory mice vary dramatically intheir sensitivity to estrogen, report researcher...tis weight inall strains of mice, strains differed dramatically in their sensitivity to estradiol. Of the treated mice, the B6 miceappeared to be most sensiti...UI research team discovers new genes involved in the spread of breast cancer
...heterochromatin-associated protein 1-Hs-alpha were dramatically decreased inthese same cells, thus suggesting their potential as tumor suppressor genes thatare lost in breast cancer. "Although the precise roles of these genes remains obscure, identifying thegenes is an important first step in understanding the c...Trouble for the world's turtles
...suming turtles for food and as medicineare growing dramatically with increased affluence and the recent convertibilityof Chinese currency. Some of the most desired species fetch as much as $1,000in Southeast Asian markets. Scientists often discover turtles that are rarelyseen in the wild in open markets and rest...Tiny mites protect vineyards from mildew
...chers learned that the tydeid mites are capable of dramatically reducingpowdery mildew. In one experiment, the mites reduced by 85 percent the powderymildew's mycelia, the part of the fungus that penetrates and robs the leaf ofnutrients. Cleistothecia, the stage of the fungus that overwinters, was reducedby an...Study details genetic basis of aging -- and how it might be delayed
...n understanding how a reduced-calorie diet worksto dramatically slow the physical manifestations of aging, many of the samegenes that exhibited changes in activity with aging in mice on a standard dietremained almost completely intact in mice on a reduced diet. "This is a leap in our understanding of how caloric ...New hope for self-injury sufferers
...est research indicates thatsufferers can be helped dramatically by combining communication training with aregimen of the drug naltrexone, which blocks the brain's opiate receptors. "This particular combination of therapies works because many people with severedisabilities self-injure either as a means of communi...Enzyme inhibitor reduces cardiac cell death in heart attack
...biochemical cascade but also protects hearttissue, dramatically reducing the amount of myocardial death by over 30 percent. Vincent L. Cryns, M.D., and colleagues in the Feinberg CardiovascularResearch Institute at Northwestern published the results of a study onprogrammed cell death and heart attack in t...USGS fire research in the southeast
... effects of fire are not subtle. Frequent fire can dramatically change thestructure of a forest; for example, it can change a forest from one with thickunderbrush to one with a parklike, cathedral structure. But while fire isessential to the maintenance of some ecosystems, it has long been viewed solelyas a destr......es M.Falk--reports that Pfiesteria outbreaks may dramatically affectconsumers' seafood eating habits and travel choices. "According to our survey," Falk points out, "a Pfiesteria outbreak couldreduce tourism in an affected area by at least 40 percent, significantlyimpacting coastal communities." Seafood sales...New hope for declining U.S. honeybee population
..., perhaps, but not honeybees. Parasiticmites have dramatically reduced the honeybee population in this country,wreaking havoc on commercial bee farms and threatening farmers who rely on beesto pollinate their crops. Researchers with the U. S. Department of Agriculture in Beltsville, Md., reportthey may be able t...National Institute on Drug Abuse launches National Drug Addiction Treatment Clinical Trials Network
...st Drug Abuse Treatments In an effort to dramatically improve treatment throughout the country,the National Institute on Drug Abuse (NIDA) has awarded $55 million in grantsover five years to establish a clinical trials network that will more rapidlymove promising science-based drug addiction treatments ...Scientists uncover possible cause of colitis
...EP enzyme orblocking substance P with a drug - can dramatically reduce the inflammation. Substance P-blocking drugs are already under development to treat depression,asthma and other conditions. If studies show that NEP and substance P play asimilar role in humans as they do in the mice, then drugs already in ...Changing children's diets today could reduce bone problems 70 years from now
...rsing homecosts. But future costs could be reduced dramatically with dietary changesduring the pre-adolescent years. "Before puberty is the important time to getcalcium, before the body begins growing rapidly in adolescence," says Dr. Zemel."Adults can receive some benefits from taking calcium supplements, but th...Revolutionary genomics project launched
... full DNA sequence of its genetic material -- have dramatically changed the study of biological systems," said Mark McNamee, dean of the Division of Biological Sciences. "These genomics studies will greatly advance our understanding of living systems. They have enormous implications for progress in human and ve......leneck or crash in the human population might have dramatically reduced its genetic diversity. "The results show a strikingly lower amount of variation in humans than in chimps," said Pbo. "The simplest explanation for this is that at some rather recent point in the past, humans have been few in numbers. From a g...Stream research supports better watershed management
...edfor agricultural production. The transformation dramatically modified geomorphological and ecologicalconditions associated with the rivers and streams. An ongoing debate has focused on how thesemodified waterways should be maintained, or whether they should be restored. "Stream restoration means a return to ...Expect rapid, pervasive innovation in 21st century
...ess sensors, a new class of miniature devices that dramatically speed up medical and biologicaltesting, and electr...reating a new class of miniature sensors that will dramatically speed up the searchfor therapeutic compounds from plants and animals in the rain forests and oceans.......s into cholesterol. Studies show that statin drugs dramatically lower cholesterol levels in high cholesterol patients, reducing rates of coronary heart disease and stroke and lowering the risk of dying from these diseases. Statins such as lovastatin, simvastatin, pravastatin and others have been widely used for o...El Niño's dramatic impact on ocean biology and carbon dioxide captured by unique monitoring system
... issue of the journal Science, El Niño also dramatically reduced the amount of carbon dioxide normally released into the atmosphere by the equatorial Pacific Ocean. Data from an array of instruments on buoys, on ships, and in space, including NASA's Sea-viewing Wide Field-of-View Sensor (SeaWiFS), gave res...