UCSF finding offers provocative insight into what drives cancer
...ns, working in combination, says Evan. c-Myc alone drives cell growth but this is overcome by cell death. Bcl-xL alone keeps cells alive but shuts down their growth. Only when you get the two together do you get this remarkable cooperation. The chances of two such mutations occurring together are very low, ...New process makes genome sequencing more efficient
...nocking down costs by $750 million. The thing that drives up the time and cost to sequence a genome is its vast number of relatively meaningless DNA sequences. "Repetitive sequences complicate all aspects of gene and genome research," Paterson said. These highly repetitive sequences are, in essence, geneti...Extreme climate variance sped extinction of local butterfly populations, researchers say
...ne is develop a model describing how precipitation drives the changes in population numbers of the butterfly," says co-author Carol Boggs, director of the Center for Conservation Biology and an associate professor (teaching) of biological sciences. "We looked at how precipitation has changed locally in the ...Molecular 'motor' drives rotavirus replication
...called NSP2 appears to be the molecular motor that drives replication of rotavirus within cells lining the g...ovide some mechanistic insights into how it either drives viral genome replication or packaging during the assembly of the new viral particles within the cell...Can we enlist substitute genes to fight muscular dystrophy
...ch then binds to a specific region of the DNA that drives the utrophin gene. Once attached to DNA, Sp1, along with another heregulin-stimulated transcription factor called GABP /, attracts the cellular machinery responsible for transcribing genes into proteins. The utrophin protein bears m...Insect yields clues to evolution of species
...st plant smell, size, or a combination of things drives this reproductive isolation," said Sandoval. "This is an example of speciation in process." Additionally, information from DNA sequences revealed that such divergence in mating preferences and morphology has evolved numerous times in this species, ac...Protein complex found to regulate first step in human blood clotting
...how that Arp2/3 complex is a cellular machine that drives a human blood platelet to change shape into a larger, more flattened form and begin the process of clotting. The link between what happens at the surface of a platelet and the mechanism of shape change within it has mystified scientists for decades. ...Rats depleted of salt become sensitized to amphetamine, show unusual growth of brain cells
...ith regulating motivated behaviors of such natural drives as those for food and salt, and for artificial rewards provided by drugs. The findings are published in the current issue of the Journal of Neuroscience. "This number, 30 to 35 percent, is startling and implies an ability for neurons to make more c...Promising new therapies for deadly form of leukemia
... two new drugs that inhibit a specific enzyme that drives development of the deadliest form of AML. It is hoped that the two drugs -- and others now in clinical trials -- will pack the same potent punch that has made Gleevec (STI571) so effective against chronic myelogenous leukemia. The scientists reported...Molecular clues to an inherited epilepsy
...trical discharge called an action potential, which drives brain activity. Shortly after they open, though, the sodium gates automatically swing closeda process called inactivation. They remain closed for a period of time to protect the cell from a repeat action potential. "The inactivation process is a wa...Men die young, even when they're old
...er for potential mates. This rivalry could be what drives them to take greater risks, with the result that men have evolved greater reproductive success at the expense of longevity. The same may be true for chimpanzees and even fruit flies, says Nesse....'Fowl-howl' ties discovered between birds, monkeys
...entially none. "A focus is now trying to see what drives that variation," he said. Densities of howler monkeys also vary. Numbers trapped on various islands by the flooding were "essentially determined by random chance," he said. Still "we do have some evidence to support my hypothesis," Feeley added. "T...Hormone found to reduce appetite by a third
...oing programme at Imperial, looking into how human drives work, of which appetite is an important example. To test if PYY3-36 is effective, twelve volunteers were infused with either PYY3-36 or saline for ninety minutes in a double blind randomised crossover trial at Hammersmith Hospital, London. Two hours...Molecular architecture and action of a proton pump
...intracellular pH. The resulting membrane potential drives the uptake of other ions and nutrients. Hence, the...e molecular motions and the release of energy that drives the pumping process. A synthetic peptide of these 38 amino acids stimulates the pump's activity by m...Genetic diversity necessary for optimal ecosystem functioning, according to UGA research
...iod," said Hunter. "Plants capture the energy that drives the planet. By continuing to destroy plant habitats, we reduce the available gene pool. In the end it could harm the biggest ecosystem of all: planet Earth."...Gene could hold key to predicting, combating life-threatening abnormal heart growth
...calcium sensor called calcineurin is activated and drives heart-muscle growth. The researchers showed that HDAC9 counteracts the calcineurin activity to short-circuit muscle growth. While the gene doesn't completely stop heart enlargement, UT Southwestern researchers showed that HDAC9's presence significant...Wisconsin team engineers hydrogen from biomass
...st first be made. The platinum-based catalyst that drives the reaction is expensive and new combinations of catalysts and reactor configurations are needed to obtain higher hydrogen yields from more concentrated solutions of sugars....UT Southwestern researchers ID key protein for communication within central nervous system
...hin the body. The process of synaptic transmission drives communication between neurons in the brain and underlies all brain function. This is only the second study that cites the initial events leading to the formation of synapses in the central nervous system, said Dr. Thomas Biederer, a postdoctoral rese......g gets wet. The interaction of water withsurfaces drives a wide variety of important phenomena that includewetting, corrosion, ice-melting, electrochemistry, dissolution, andsolvation. Such interactions are equally important to many biologicalprocesses as well. Despite the broad concern, the interactions ......have investigated precisely how visual stimulation drives the formation of new neuronal structures in the brain. Now, researchers at Cold Spring Harbor Laboratory have demonstrated that visual stimulation causes particular neurons in the brains of tadpoles to sprout new branches, and that such branching req...