Why does cloning create abnormalities? Scientists take a step towards finding out
...that far", said Dr. Takeuchi. "This appears to be due to the abnormal gene expression we saw in the cloned group. This not only explains the developmental impairment of the cloned group, but may in future be helpful in identifying environmental culture condition that are deleterious to the development...In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...ss a key question of whether regaining loss weight due to dieting is caused by metabolic or behavioral changes. The common belief is that the metabolic state after weight loss promotes weight regain. However, data germane to this supposition has been controversial and equivocal. The failure to reach d...New milestones on the path to conquering HIV drug resistance (AIDS)
..." Arnold said. The success of the compounds may be due to their ability to assume different shapes, allowing them to adapt to the changing shapes found in the virus's repertoire of drug-resistant forms. Arnold describes the DAPY antics as "rolling with the punches, wiggling and jiggling around until they...The first domesticated donkey was born in Africa
...rica approximately 5,000 years ago, quite probably due to the desertification of the Sahara. The conclusions of the study state that all domesticated donkeys come from two different lines from northeast Africa. Donkeys were the last species of domestic livestock (cows, sheep, goats, horses, pigs, etc.) t...Endometriosis: Could angiostatic therapy be the new treatment of the future?
...atment for endometriosis is highly unsatisfactory, due to strong side-effects and a high rate of recurrence. It is, therefore, imperative to find a new therapeutic strategy. Endostatin or other angiogenesis inhibitors could be one of these approaches."...Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
... adult mouse brain structures have been conducted, due in part to the laborious process required to obtain such data. Using conventional histology, it would take months to section brains, measure various structures and perform a 3D reconstruction, whereas Koshibu obtained statistically relevant results i...Hope Clinic of Emory Vaccine Center receives CDC contract
...ingly in the South, in African-American women, and due to heterosexual transmission. Further development and clinical testing is needed to identify a safe and effective microbicide. Although some candidate microbicides have been tested in clinical trials, most are in early-stage studies, and the only o...Evidence for fat hormone target in brain
... the mice had significantly increased body weight, due to an increase in fat mass. Surprisingly, however,...heorize that the reduction of POMC neuron activity due to lack of leptin signaling triggers compensatory mechanisms that reduce the impact on the animals' ...'Mighty mouse' gene works the same way in people
...team show that the child's extra-large muscles are due to an inherited mutation that effectively silences the myostatin gene, proving that its protein normally keeps muscle development in check in people. People with muscle-wasting conditions such as muscular dystrophy, and others just wanting to "bulk ...NASA scientists get global fix on food, wood & fiber use
...lower. Technology helps reduce waste. For example, due to better technology, one ton of milled lumber requires 1.3 tons of trees in industrialized countries but more than 2 tons of trees in developing countries. As a technologically advanced country, U.S. use of NPP is close to the global average. Ea...Origin of West Indian insect eater much older than previously thought
...their relatives. They are now, however, endangered due to the deforestation of their habitat on the islands of Cuba and Hispaniola. "For the first time we have a good idea of where solenodon fits into the phylogenetic tree," Springer said. "The timing of the divergence tells us a lot about early ...Researcher issues caution on live virus vaccines
...e should be approved by an international authority due to safety concerns, the authors write. The article lists five main lessons learned from other live virus vaccines: reversion of vaccine strains to increased virulence; development of disease in individuals with compromised immune system...Improved nutrition could prevent more than half of the world's child deaths annually
...at showed that 55 percent of all child deaths were due to undernutrition. However, the new analysis went further. It examined whether the risk of dying due to being underweight varies by cause of death. Using data from 10 large cohort studies from sub-Saha...UK researchers develop way of predicting a woman's 'reproductive' age
...be reliable that variation in age at menopause is due to wide variation in the number of follicles present at birth, and that ovarian volume between the ages of 25 and 50 is directly related to the remaining number of follicles. The researchers are currently involved in clinical studies on young women s......n of the efficacy of these strategies is difficult due to the lack of accurate means to measure the thera-peutic effect. Now, Sinusas and colleagues, by radioactively labeling a protein that is present specifically in newly developing blood vessels (a protein called avB3 integrin), have found they could ...JCI table of contents, 15 June 2004
...n of the efficacy of these strategies is difficult due to the lack of accurate means to measure the thera-peutic effect. Now, Sinusas and colleagues, by radioactively labeling a protein that is present specifically in newly developing blood vessels (a protein called avB3 integrin), have found they could ...Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics
...damaged tissues in the case of elderly patients or due to presence of cancer in the bone marrow. In addition, ASCs are restricted to the individual patient, making it difficult to spread the cost of isolation and expansion among multiple recipients. Some groups have found, however, that certain ASCs do n...Existing drug may prevent brain injury and seizures in newborns
...zures in newborns. Infants with neonatal seizures due to hypoxia-ischemia can develop epilepsy, often in... infants at risk for PVL and for neonatal seizures due to perinatal hypoxia. "By further studying unique mechanisms of injury in the newborn brain, w...Ecosystem bounces back from hurricanes
...ne Fran, large amounts of fish kills were reported due to oxygen depletion and high concentrations of con... as in 1996, but no major fish kills were reported due to the enormous amount of flooding that diluted the pollution, Burkholder says. Diminished levels of...Two billion vulnerable to floods by 2050; number expected to double or more in two generations
...flood is expected to mushroom to 2 billion by 2050 due to climate change, deforestation, rising sea level...le living in flood-prone areas will roughly double due to: more extreme weather systems that accompany global climate change, rising sea levels; and ...