Tag: "earlier" at biology news

New Cancer Switch Discovered By Duke Medical Center Pharmacologists

... sending the cell proliferating out of control. In earlier work, Pendergast and her colleagues found that the outlaw BCR-ABL protein plugs into an adaptor protein called GRB-2 to switch on a chain of other enzymes that eventually activates the cancer gene, or oncogene, called ras, which launches uncontrolled...

Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"

...ny ways, "this finding may be morepivotal than our earlier work," said Dr. Allen Roses, scientific directorof the Deane Laboratory at Duke, where the experiments were conducted. "Weare beginning to cross the difficult area between gene discovery and abnormalfunctions of the brain, and to open the door to tar...

Tumor Suppressor Gene Located In Liver Cancer Cells

...trengthened their suspicion. In research published earlier this year in the journal Oncogene, Jirtle's team found that liver tumors from 64 percent of patients studied had lost one copy of the gene. The deletion of one copy, or allele, means that a mutation in the remaining copy can limit or destroy a cell...

New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics

... spirals away in a clockwise direction. In earlier research, Raetz and his colleagues had discovered that the aminoacid sequence of the LpxA enzyme contained sequences similar to severalother enzymes with similar function, although the three-dimensional structureof the enzymes had not yet been determ...

Dating A Caveman

... that the fossils date from at least 100,000 years earlier than scientists previously believed. Ku dated the limestone caverns in which Peking Man dwelled at Zhoukoudian, not far from Beijing. In excavations that began in 1921, archeologists and paleontologists have recovered the remains of at least 40 indiv...

Duke Researchers Find Second Gene Linked To Blood Vessel Disorder

...vide, making TGF-_ an excellent wound-healer. In earlier research, reported in the December 1994 issue of Nature Genetics,Marchuk identified the first gene linked to HHT. This gene, called ENG,is located on chromosome 9 and encodes a protein called endoglin, whichalso appears to bind TGF-_. He hypothesi...

Cornell Researchers Precisely Date Wood From Ancient Tomb In Turkey

...ntil the lines match up, and their knowledge of an earlier climatic event. Previous research has shown that t...that she held the throne by then -- which supports earlier historical findings. Elsewhere, juniper and cedar logs from the walls of the Middle-Bronze-Age palac...

Duke Primate Center Sets October Expedition To Find 'Juliet'

...rightly coloredsifakas easy prey. "In fact, on an earlier visit, when I tried to explain to the nativeswhich animal I was looking for, they told me they called this animal 'It-takes-two-days-to-eat,'" Simons said. While the natives have traditionally used blowguns for hunting the animals,it is now easier f...

Newly Discovered Gene Halts Cell Division and May Have Cancer Link

...was p53, which allows a cell to copy its DNA at an earlier phase in the cell cycle. Defects in the p53 gene are known to be involved in about half of all tumors. The MAD2 gene allows a cell to commit to divide only after the gene checks to ensure that chromosomes, which contain DNA's genetic blueprint, are ...

Researchers Find Genetic Clues To Intestinal Disease

... the best treatment for each individual. "Although earlier studies had suggested that Crohn's disease might b...cet, the researchers found that the disease occurs earlier in life in people whose parents also have a history of Crohn's disease. This type of earlier onset o...

NCAR Scientist Models Earth's Climate and Vegetation Patterns At Last Glacial Peak

... Southest Asia. Felzer checked his results against earlier LGM vegetation scenarios based on data from fossilized pollen retrieved from lake cores. His simulated vegetation matched up fairly well with these geological reconstructions of plant life. Where differences exist, a colder simulation might help prod...

An Equal Opportunity Extinction? Cincinnati Geologists Find Global Impact from Permian Die

...ing." Ebersole said his results are similar to the earlier findingsby David Raup and David Jablonski on the extinction of molluscsin the Late Cretaceous. Raup and Jablonski also found nosignificant differences in extinction rates from one region toanother....

UC Berkeley, U.S.G.S. Scientists Discover Microscopic Invader Of San Francisco Bay, The First Known Marine Microbe Invader Of U.S. Waters

... then looked at many sediment samples collected in earlier years from the bay, to see if they could determine when it first arrived. While they did not find it in any sediment samples which had been collected between 1964 and 1981, they did find it in samples collected from the bottom of the bay in 1987. Ev...

Study Examines How Mechanisms Evolve To Regulate Bee Development

...el was elevated, dronesbegan to seek virgin queens earlier than same-aged drones whose levels werenot altered...n looking for a mate earlier, but drones that mate earlier in life dieearlier....

Genetic Makeup May Explain Why Some Women Smokers Develop Breast Cancer While Others Don't, UB Study in JAMA Reports

...r among smokers, the researchers used data from an earlier case-control study of the disease. Extensive data were gathered on medical and reproductive history and blood samples were collected for DNA analysis. Researchers were able to obtain genetic data from the blood samples of 398 postmenopausal women (...

Prostate Cancer May Be Predicted 10 Years Before Diagnosis

...ict a diagnosis of prostate cancer up to six years earlier than current prediction methods. This discovery by researchers at the National Institute on Aging (NIA) and colleagues at the Johns Hopkins University School of Medicine is published in the December, 1996, journal, Urology. PSA, an enzyme produced ...

ORNL Mice Helping Researchers Isolate, Identify Causes Of Cancer

...ing of the development of certain human cancers,to earlier diagnoses and to better treatment strategies. This research was funded by the National Cancer Institute and the AmericanCancer Society. ORNL, one of DOE's multiprogram research facilities, is managed by LockheedMartin Energy Research Corp. You may re...

Malnutrition Impacts Longevity Of Females More Than Males And Shows Gender Differences In Fruit Flies

...versity of California, Davis. The results support earlier findings by the same scientists indicatingthat lif...ale Medfliesthan for their male counterparts. This earlier flattening of the femalemortality curve was observed in protein-deprived medflies studied in the1992...

A Drug Pump On A Computer Chip

...rt Structures and Materials Symposium in San Diego earlier this month. The field of microelectromechanical systems and micro fabrication research has led to the development of micro devices which have feature sizes down to a micrometer or less. The field, which developed from integrated circuit fabrica...

Hot 'Lanta: NASA, School Kids Team To Study How Trees Help Cities Keep Their Cool

... The Atlanta experiment was scheduled to start no earlier than May 5, depending on weather conditions and aircraftavailability. Results will become available later in the fall. Even the kids will participate - they'll get CD-ROMs with copiesof the images taken over their schools....

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