Tag: "earlier" at biology news

Harvard Medical School Researchers Present Atomic Structure Of DNA-Replicating Enzyme Widely Used In DNA Sequencing

...every livingthing, but the enzymes crystallized in earlier studies function more like repairenzymes that fill in small nicks in the DNA. They are slow and make errorsfrequently. This structure, however, shows a polymerase that zips along the DNAduring cell division and faithfully replicates the entire chromo...

Experimental Trial Combines DNA Vaccine With Triple-Drug Therapy To Stop HIV

...r example. So, it was counterintuitive to me inour earlier DNA vaccine trial with HIV-positive patients that there would be anincreased immune response over that produced by the virus already circulating inthe body. In that trial, however, we saw a statistically significant, measurablerise in antibodies agai...

Gene Therapy Enables Transplantation Without Immunosuppressive Drugs

...at destroys the invader tissues. In fact, earlier research has shown that if the pathway for thecostimulatory signal is blocked at the time of foreign antigen presentation --at the time of surgery and in the period immediately thereafter, in this case --then the T cells become permanently tolerant o...

Low Cholesterol? Reduced Sodium? What Do These Terms Really Mean?

...ct only once to prevent subjects from referring to earlier answerswhen responding. Each label was presented on its own page of the booklet. Theorder of presentation of stimuli within each booklet was counterbalanced. At thebottom of each page, a survey question was printed. The question asked thesubject to r...

NIAID Doctor Successfully Treats Longest Case Of Malaria Infection On Record

...tory indicated, was first documented several years earlier during a routine examination in Greece. At that time, she was mistakenly diagnosed with lymphoma and treated with an oral anti-cancer drug, methotrexate, for 10 days. In response to the chemotherapy, symptoms of...

American Heart Association Comment: "Folate And Vitamin B6 From Diet And Supplements In Relation To Risk Of Coronary Heart Disease Among Women"

...heart disease). These results are consistent with earlier data indicating a relationship offolate intake with coronary disease risk in men, and with other evidence thatlow blood levels of folate and vitamin B-6 are indicative of increased heartdisease risk. Although the present study did not include measur...

Microsurgery Made More Accurate With Virtual Measuring Tool

... and precision. Whereas experimental assessment of earlier implementations of the VTM have demonstrated very good performance on a macroscopic scale [Milgram 1997, Drascic 1991], no results have been reported in the literature on precision and accuracy of the VTM on a microscopic scale. The present experimen...

TSRI Scientists Discover Naturally-Occurring Mechanism Involved In Regulation Of Angiogenesis; New Anti-Cancer Therapeutic Agents Are Suggested

...upply to provide nourishment and remove wastes. In earlier studies,the Cheresh laboratory demonstrated that angiogenesis is dependent on theoccurrence of specific biological events mediated by one of the integrinreceptor molecules found on newly sprouting blood vessels. In experimentsperformed in 1994, they ...

Study Finds Gene Is Associated With Higher Risk Of One Kind of Stroke Among African-Americans

...ese strokes occurred inAfrican Americans at a much earlier age -- on average, more than seven yearsearlier. ...with the e4variant tended to get the disease at an earlier age. Since that time, theseresearchers, some of whom participated in the current ICH study, have sin...

Low B Vitamin Levels Common In Many People Linked To Increased Heart Disease, Stroke Risk

...abolism of meat and dairy foods, has been shown in earlier research to damage the lining of blood vessels. Low levels of vitamin B-6 can lead to elevations in homocysteine.Regarding the surprising finding about normal levels of homocysteine in people with low B-6 and increased risk for cardiovascular diseas...

High Testosterone Level May Lead Male Junco To Stray From Mate

...y then show less interest in other females, and an earlier study in thisproject demonstrated that they are more likely to help feed and care fortheir young. “In this study, we manipulated some males so they always had thehigh level of testosterone that they would normally only have early in thebreeding...

At Life's Most Sensitive Stage, Embryos Cope With Stress

...ls the "clencher" work - showing that, contrary to earlier assumptions, highwater motion inhibits gamete release. Brawley's lab now is working on the details of what happens inside the seaweedto inhibit or trigger gamete release. They also are studying how the embryos ofFucus fare once fertilization is succe...

Emerging Field Of Industrial Ecology

... philosophy in which companies are revertingto the earlier approach of making modular components that can be replaced whenthey wear out or become obsolete. Some laptop computer companies, for example,advertise replaceable keyboards, interchangeable screens and alternative discdrives. Find the ne...

Prairies Will Be Hit Hard By Global Warming

...ns. As the climate warms,these marshes will dry up earlier and farmers will be tempted to use these dryconditions to cultivate their fields earlier. This will force the birds to flyfurther north for acceptable nesting areas. Malcolm says a changing climatecould cause even further upheavals in an ecosystem th...

USC Study On Soy's Anti-Cancer Effects

...e) important in cellgrowth and differentiation. In earlier studies, Lee had found that it could alsoblock the stress response. "But until now the targets of genistein action havenot been well understood. Our work provides a molecular mechanism for genisteinaction at the DNA level. We predict that other genes...

UPMC Researchers Report On Gene Therapy Advances

...pe that the next trial will involve intervening at earlier stages of thedisease, with the intent of eliminating or delaying the need for surgery." The early phase of this research in humans is not designed to treat disease, butto ensure the safety of the procedure and to confirm that gene transfer to humanj...

Sex Differences In Heart Disease May Be Due To Enzyme That Breaks Down Fat

...as LDL -- mayexplain why men develop heart disease earlier than women, say scientists todayat the American Heart Association's epidemiology and prevention conference. "There are gender differences in the risk of coronary artery disease,the cause of heart attack. Pre-menopausal women have lower chole...

Wake Forest Study Shows Soy Containing A Key Ingredient Is What Lowers Cholesterol

... had showed variable results, though overall these earlier studies did show a reduction intotal cholesterol, LDL and triglycerides. But none of these earlier studies attempted to determine whether thecholesterol-lowering effect came from the soy protein or f...

Gene-Reading Problem Linked To Lou Gehrig's Disease

...elp us make the diagnosis and begin treatment much earlier in thecourse of thedisease," says Jeffrey Rothstein, M.D., Ph.D., associate professor of neurology. The newly identified mutations involve a protein called EAAT2, whichnormallydeactivates and recycles glutamate, a chemical certain nerve cells us...

Prostate Cancer Switch May Yield Map Of Cancer Machinery, Targets For Drugs

... cancer, but also new drugs to kill cancer cellsat earlier stages, the researchers said. Prostate cancers are distinguished by their tendency to linger at arelatively benign stage for many years, but to suddenly transform into a deadlyform that spreads, or metastasises, throughout the body. ...

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