Half-million dollar landmark achieved for the Methuselah Mouse Prize
...fe; it is discovering ways to limit and eventually eliminate the destructive effects of human aging, promoting not only longer life but freedom from the effects of aging-related conditions and diseases." Your support of the Methuselah Mouse Prize is the best and most effective way that you can help ensure that...Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...around the cell. Portnoy thought that if he could eliminate the gene for ActA, he could prevent the bacteria from forming actin motors and spreading from cell to cell. The technique worked, and Cerus adapted one of Portnoy's attenuated strains for its vaccine. The particular strain Cerus plans to use for its ...Researchers identify protein promoting vascular tumor growth
...cular tumor site. This means that therapies to eliminate the MCP-1 protein could be a key to healing or preventing the tumors and possibly others in which MCP-1 is expressed. The results are published in the October issue of the American Journal of Physiology (Cell). Blood vessel tumors affect up t...HHMI, NIBIB/NIH to invest up to $35 million in interdisciplinary Ph.D. programs
...g for training programs that provide strategies to eliminate or lower barriers between seemingly disparate scientific disciplines," said Peter J. Bruns, HHMI vice president for grants and special programs. The new graduate training program parallels HHMI's commitment to bring together biologists, compute...Indiana University, EPA to study airborne PCBs
...n health and the environment and work to reduce or eliminate them," Hites said. IU SPEA post-doctoral fellow Daniel Carlson and graduate students William Hafner and Eunha Hoh will also participate in this next phase of the IADN project....Reducing allergens in the home helps inner-city children with asthma
... home and work with caretakers to decrease or even eliminate these allergens." Researchers followed more than 900 children ages 5 to 11 with asthma who live in inner-city areas in New York City, Boston, Chicago, Dallas, Seattle/Tacoma, Wash., and Tucson, Ariz. Research teams went to individual households ...Common cold virus can cause polio in mice when injected into muscles
... process of eradicating polio worldwide, but if we eliminate the poliovirus and cease polio vaccinations, our immune systems wouldn't produce antibodies against polio, and Coxsackievirus could theoretically fill the niche of eradicated polio" he said. Results of the study will be published in the Sept. 6, 2004...Genetic map of important tree genes outlined
...modified for a variety of uses: bioremediation to eliminate pollutants from soil, or the production of renewable feedstocks for bioenergy and fiber products, including paper and chemicals. This process, where only native gene functions are modified, is quite different from transferring novel proteins across v...Long-term effects of carbon monoxide poisoning are an autoimmune reaction
...immune response in which lymphocytes, triggered to eliminate altered MBP, continue to attack normal MBP. Specifically, the researchers found that by-products of CO metabolism in the brain alter the charge and structure of MBP. "These changes in MBP have also been demonstrated in multiple sclerosis, which is ...Study reveals first genetic step necessary for prostate cancer growth
...using a mouse system that allows us to selectively eliminate genes in the epithelial cells of the prostate. Our experimental approach allows us to closely mimic what happens in man and gives us a glimpse into the natural history of the disease that we haven't had before." Greenberg developed a widely used gene...Green tea research leads to gum and other products
...h helped determine that green tea polyphenols help eliminate free radicals, which can damage DNA and lead to cancer. He further found that green tea-induced p57--a protein that helps regulate cell growth and differentiation--changes the behavior of healthy cells as polyphenols target cancer cells for destructi...Probing the surface of white blood cells to enhance immune system medicine
... have significant therapeutic benefits. Drugs that eliminate lymphocyte microvilli could lead to a less toxic form of immune suppression for transplant recipients. Since many cancer cells share the same mechanism of extravasation as lymphocytes, ablating microvilli could also prevent metastasis of cancer cells...First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
...ne that is given to infants using nose drops would eliminate the discomfort and complications of injections. Because the vaccine contains a live virus, it should stimulate both antibody and cellular immune responses, which together may provide durable protection from hPIV-1. In cellular immunity, special cell...New compound could give some types of cancer the one-two punch
...has to deal with a single compound, and that could eliminate a lot of complexity in terms of giving medication ...has to deal with a single compound, and that could eliminate a lot of complexity in terms of giving medication to patients, the body's ability to absorb a drug a...When is a mouse like a test tube?
... chemicals as possible. "Synthetic chemists try to eliminate all interfering chemical groups, which can be difficult in a biological system," Bertozzi said. "We design functional groups to be specific, so they don't react with the environment in the body. Ours is an elegant system, highly targeted and very sel...Protective gene may enhance vaccine responses
...at particular invader multiply rapidly, attack and eliminate infected cells. Once the infection is cleared, ho... reverse the process, suggesting ways to reduce or eliminate memory T cells responsible the unwanted immune responses that cause autoimmune diseases such as arth...Body's own defense against H. pylori, cause of stomach ulcers and stomach cancer
...mpletely eradicate H. pylori infection, and we can eliminate stomach cancer". ...Leukemia stem cells identified by Stanford researchers
...re the ones chemotherapy must wipe out in order to eliminate the disease. Treatments that destroy these cells could more effectively eliminate cancer. Current treatments destroy cancer cells indiscriminately, draining the reservoir of cancer c...Viral proteins may prevent bacterial infections
... could be delivered orally or nasally to reduce or eliminate colonization. "If you greatly reduce the number...nst the disease. The hope is that the enzyme will eliminate enough bacteria from the blood after anthrax exposure to extend the window of time during which anti......t. "We find bacteria in the accretion ice, but can eliminate most of them using our contamination database," says Bulat. Other researchers say the decontamination techniques used on the core sample, which involve washing it and removing the outer layers, would be completely effective. Brent Christner of the Mo...