UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...search programs using genetically modified mice to elucidate the metabolic and molecular bases of obesity and metabolic syndromes; and to support translation of scientific findings made in animal models to humans. Dr. Keith Parker, chief of endocrinology and director of the Jean D. Wilson Center for Biomedical...Genetic differences might help distinguish thyroid cancers
...ical Scientist Award. "Our work begins to elucidate the fundamental differences and similarities between these two types of thyroid cancer, which should help in the future to develop new therapies," Eng says. Clinical testing for the genetic differences can be done using polymerase chain reac...APS awards more than $140,000 to minority students of physiology
...ral nervous system (CNS). This research will help elucidate the neural mechanism that causes CNS oxygen toxicity. CNS oxygen toxicity is a potential health problem for hyperbaric oxygen therapy patients and U.S. Navy divers who breathe pure oxygen during their missions. Damon Jacobs University of North C...Researchers uncover secrets of immune system's munitions factory
...omplex with the cell's repair mechanism to further elucidate the somatic hypermutation and class switch recombination processes, said Alt. "We'd like to figure out how those downstream steps in these two different situations lead in one case to mutation and in the other case to recombination," he said. "Now th...Circadian clock genes reign in duration of fruit fly copulation
...ll as long time scales. Future studies should help elucidate the mechanism by which period and timeless control copulation--for example, by influencing male development or acting as components of a molecular timer....Virus known for its photo ops makes its movie screen debut
...roscopy, crystallography, and molecular biology to elucidate the processes of viral entry, replication and pathogenesis....New glycan arrays discover autoimmunogenic activities of SARS-CoV: concern over monkey vaccine
...s of the virus. They urge collaborative efforts to elucidate the structure of sugar chains that are responsible for the observed autoimmunogenic activities of SARS-CoV. In addition, they said that the experimental approaches developed in their research are likely applicable for the immunologic characterizati...K-State professor combines love of teaching, research to examine eye development
...eflex." Research to be done by the Conrad group to elucidate the normal mechanisms by which embryonic animal corneas become innervated may reveal clues by which transplanted adult human corneas can be coaxed to become innervated again....To understand innate immunity, silence the genome
...lar interactions are generally not understood. To elucidate one arm of the innate immune system in the Drosophila fruitfly, Edan Foley and Patrick O'Farrell sequentially silenced its conserved genes (over 7,000) to study the effect on the flies ability to mount an immune response. Their findings, published o...A gene that keeps species apart
...of plant crosses produce infertile offspring. To elucidate the molecular mechanisms of reproductive isolation, biologists must first identify candidate hybrid incompatibility genes. Species- or lineage- specific functional divergence is an essential trait of these genes. (That is, the genes evolve different...Existing drug may prevent brain injury and seizures in newborns
...njury in the newborn brain, we hope to continue to elucidate new therapies for use in this age group," says Jensen. "However, since agents already approved for use in adults are also effective, our results indicate that a clinical trial should be considered to determine topiramate's safety and efficacy in newb...EMBL Director-General receives high German honour: the Bundesverdienstkreuz 1. Klasse
...n 2002. The consortium developed new approaches to elucidate the genetic basis of interaction between the malar...ner in order to address immense new challenges: to elucidate complex biological systems and to orient this understanding to the benefit of society." Prof. Kafat...Insight into transplant rejection might lead to novel prevention therapies
...he team will conduct additional studies to further elucidate the interaction between the innate and adaptive immune systems following organ transplantation....Promising research: From employment issues to virology
...archers will develop new organocatalyst processes, elucidate how they function and apply them to different syntheses that are also industrially relevant. (Coordinator: Professor Dr. Benjamin List, Max Planck Institute for Coal Research, Mlheim) Atoms and electrons behave like bricks and mortar. It is the elect...New insights on sirtuins, involved in gene expression and aging
... Wistar Institute report new findings that further elucidate how sirtuins work and suggest how scientists might identify or design an activator to boost sirtuin activity using a structure-based approach. The research will be published Tuesday, May 18, in the Proceedings of the National Academy of Sciences. "......ylation and premature aging in mice. "In order to elucidate the function of PASG, we generated a "knockout" mouse carrying a hypomorphic mutation of PASG. Using homologous recombination, exons 10, 11 and 12 containing helicase domains II, III and IV were deleted," states Dr. Arceci. These PASG-mutant mice di...Fly with brain tumor may shed light on cancer causing genes
...on that they have gathered from this experiment to elucidate which of the genes upregulated in these cancer cells are responsible for the cells' metastatic behaviour....Keck Futures Initiative announces grant recipients
...g and executing experiments to verify, refute, and elucidate these hypotheses in the most efficient way. The research will first be applied to the well-studied lactose and arabinose gene regulation systems in E. Coli, paving the path towards automated reconstruction of more complex, unknown systems in the futu......ioural studies and field observations will have to elucidate what these needs might be. Perhaps the mole-rats still come to the surface every so often. At present we know too little about the visual challenges and capabilities of these animals. Certainly, the hypothesis of a general, convergent reduction of th...... the scientist now hope to extend their studies to elucidate the role this gene plays in shaping the architecture and function of brain circuits that control song learning and song production. "The discovery of FoxP2 in birds is only the beginning, there is no direct evidence yet that the gene is necessary for...