Ovarian stimulation in mice adversely affects embryo development and implantation
...eggs appears to impair both the development of the embryo and its likelihood of implanting in the uterus. Dr... undertook the study to establish whether impaired embryo quality or changes in the environment in the uterus could be responsible for the observed adverse ef...Vitamin A activates gene to guide kidney development
...per, Dr. Mendelsohn and others showed in the mouse embryo and cultured embryonic mouse kidney that depriving the fetus of vitamin A could drastically reduce the amount of ret in the developing kidney tissues and also disrupt formation of kidney structures. Deleting the RAR gene, presumably necessary for vit...Disconnect between skin cells implicated in common skin cancer
... knocked-out, selectively in skin cells. The mouse embryo developed normally until its skin and hair begin to develop, around the 14th day of gestation. As these specialized cells, called keratinocytes, developed they did not make adherens junctions. The alpha-catenin needed to anchor the junction was missi......olating cells from the ventral endoderm of a mouse embryo and for culturing the cells in the laboratory, allowing the researchers to closely follow the generation of the liver or pancreatic cell lineages. Earlier, they used this culture method to show that fibroblast growth factor (FGF), a signal secreted f...Zebrafish could become genetics 'lab rat' of choice
...e knockout technique works a genetically modified embryo cell, called an embryonic stem cell, is inserted i...g mouse embryo. An embryonic stem cell is an early embryo cell that has not yet begun to differentiate into various tissues. The embryo is then transferred in...Antarctic sea urchin shows amazing energy-efficiency in nature's deep freeze
...ummer months and take about a year to develop from embryo to larva to juvenile a stage that is a miniature version of the adult. To collect sea urchins for their study, Marsh and his colleagues traveled periodically to McMurdo Station, a research outpost on Ross Island, Antarctica. The scientists cut...Calcium signals found to guide nerve cell development
...covered that growing nerve cells in the developing embryo are guided to their proper targets by bursts of intracellular calcium that probe what's ahead and send back information to the cells in a kind of biological Morse code. In a paper published in the March 9 issue of Science, the researchers report thei...The Frozen Zoo: the University of New Orleans and the new world of saving endangered species
...tive technologies such as artificial insemination, embryo transfer, in vitro fertilization, embryo splitting, and inner cell mass transfer with the goal of repopulating them in their original habitat...Sonic Hedgehog shapes the brain
...a major division of the central nervous system, of embryo chicks. The midbrain was an attractive model for ...or Sonic Hedgehog into the midbrain of two-day-old embryo chicks. The brains were examined when the embryos were five days old, when all the midbrain arcs are......ntly, the new study reveals that the effect on the embryo is influenced by the stage of egg follicle develop...ues mean that many centres offer egg retrieval and embryo freezing before starting cancer treatment that is likely to result in infertility. But delaying life...Extinction claims a furry friend
...ation. "The crucial factor is getting a newly born embryo at a critical time. That means knowing when these animals are going to mate and breed," saidDr Hornsby. "The conventional physiological way of doing this means that you've got to catch the animal and get urine or faecal samples," hesaid, "Whereas it...San Diego chemist wins national award for protein discoveries
... protein kinases, directing differentiation in the embryo to regulating adult metabolism. Taylor's most outstanding contribution, published in 1991, was solving the three-dimensional structure of the first kinase, called cyclic AMP-dependent protein kinase. Making the leap from sequence on paper to 3-D pict...Hopkins' Young Investigators' Day winners shine in the spotlight
...sease. Matthew R. Wallenfang has studied early embryo development in the worm model, C. elegans. Specif...o an egg triggers formation of microtubules in the embryo that, in turn, direct the rearrangement into a definite head and tail end of the developing animal. ...Researchers use cloning technology to produce embryonic stem cell lines from adult mice
...m the cells of a region of a preimplantation mouse embryo called the inner cell mass. These embryos, which are no more than a ball of cells called a blastocyst , can be grown in a laboratory dish. Nuclear transfer (nt) was used to produce cloned blastocysts from which the ES cell lines were derived, and the...UCSD biologists discover new class of genes responsible for embryonic development
...etric division of the first cell in the developing embryo into an unequal sized pair of cells. "The actual .... "If the asymmetrical division is screwed up, the embryo is never going to make it," says Akiko Tagawa, a graduate student and the lead author of the paper, ......t a second copy of a human sex gene can convert an embryo from male to female, often resulting in ambiguous ...any stage in the genetic blueprint, it changes the embryo from male to female." The UCLA team's findings will enable physicians to use molecular testing to id...DNA gene chips and novel software used to describe kidney development
...mammalian kidney, from its early beginnings in the embryo to its adult role as a vital filtration system, ha...ney, how it regenerates and how it develops in the embryo are variations of the same broader question: how do you make a kidney?" The study's lead author, ne...Presbyterians vote in favor of fetal, embryonic, and stem cell research
...rch. Our respect for life includes respect for the embryo and fetus, and we affirm that decisions about embryos and fetuses need to be made with responsibility. Therefore, we believe that the Presbyterian Church (U.S.A.) and other faith groups should educate their members in making these very difficult ethi...Gene that directs fate of many embryonic stem cells identified
...al that has become a powerful model of early human embryo development. Strong evidence indicates that the pivotal gene plays the same role in humans as it does in zebrafish: inducing embryonic stem cells to produce endoderm, the source material for many specialized cells and tissues, including the pancreas,...