Multiple births - their risks and how to prevent them
...c - caused by doctors. If we only transferred one embryo to the uterus during IVF and if we always meticulo...er 32% is possible as against less than 23% if the embryo is transferred at only day 2 of its fertilisation. Lead investigator Professor Jean Luc Pouly from ...PGD could save women from the agony of repeated miscarriages
...antation failure, chromosomal abnormalities in the embryo can be the cause of the problem. High pregnancy rates and a decreased risk of further miscarriages can be achieved in these couples by using PGD to select only the normal embryos to be transferred into the uterus. PGD could also be used as a diagnos...Researchers produce motor neurons from embryonic stem cells
...ch to identify the chemical cues in the developing embryo that coax "nave neuroprogenitor" cells to differentiate into spinal cord motor neurons. These chemical signals "direct" ES cells down a developmental pathway in successive stages --first into neurons and ultimately into ever more specialized spinal c...Finding sheds new light into mysterious process of cell movement during development
...tates the movements of cells within the developing embryo of the zebrafish, a small fish that has become an important animal model for studying the development of vertebrates, animals with backbones. The researchers report that this protein plays an essential role in directing the migration of cells withi...Joint Genome Institute to sequence key African frog genome
...al processes as cell division and how cells in the embryo communicate with one another. Because these are the processes that go awry when birth defects occur or cancer strikes, we must seek a better understanding of them. This genome project will provide a major step in that direction." The JGI, one of the...A unique hemoglobin may help the baby kangaroo's journey to the mothers pouch
... ways, the newborn Tammar is equivalent to a human embryo at seven weeks of gestation. The blood of the new...s present in most of the hemoglobin present in the embryo and newborn. It showed no special features that would account for the special respiratory properties...One gene, two important proteins
... turned to developing fly embryos. Normally, a fly embryo develops in a segmented fashion: seven stripes con...d" form along the length of its body, dividing the embryo into eight segments. From previous experiments, the researchers knew that a defective STAT92E gene w...Study: Genome-wide scanning unravels complex birth defect
...in connecting nerves to the digestive tract during embryo development....Crucial gene found for embryonic stem cell maintenance
...cell mass to expand normally, and thereby form the embryo proper and some of the supportive extraembryonic tissues (ie., allantois and amnion). The researchers also found that embryonic stem cells, which are derived from the inner cell mass, could not be generated from Foxd3-deficient mouse embryos. Furthe...Foxd3 gene allows stem cells to remain stem cells
...pes of tissue holding back the process so that an embryo will have enough stem cells to continue developing...ping embryos fails to expand enough to produce the embryo and some of the supportive tissues. Without Foxd3 , the mouse embryos simply could not maintain eno...Ovary gene may explain certain aspects of infertility
...ce and humans and offers promise for understanding embryo loss, birth defects, and infertility in women. The study appears in the December Nature Cell Biology. "As humans we are incredibly bad at producing eggs with the normal number of chromosomes, which is the leading cause of pregnancy loss in women," ...Newly-discovered role for Nf1 gene explains heart abnormalities associated with neurofibromatosis
...ls of the developing neural crest the part of the embryo that forms the peripheral nervous system," said Jonathan A. Epstein, MD, associate professor in the Cardiovascular Division of Penn's Department of Medicine. "NF1, however, is associated with cardiovascular problems, which our findings could explain ...Observing proteins and cells in the wild
... worm C. elegans continuously from its birth in an embryo to its final destination in an adult three and a half days later," says Jaiswal. Interestingly, the researchers discovered that they could label the cells with quantum dots using a natural process known as endocytosis, whereby cells engulf vitamins a...European scholars support development of germ line modification
...human embryo, and some oppose any treatment of the embryo in vitro. This opposition results in a clear rejection of most experiments that are currently carried out to develop the technology of IGM in humans. It may also result in the rejection of some scenarios involving the use of human IGM. C. Five major ...Knocking the Sox off early mammalian development
...in mammalian development, a pre-implantation stage embryo called a blastocyst forms. The cells of the blasto...er with trophoblast cells, give rise to the entire embryo and its associated tissues: epiblast cells differentiate into all the cell types of the embryo, hypo...New role for tamoxifen as fertility drug for breast cancer patients?
... stimulation, but typically, no more than a single embryo can be achieved for immediate use or freezing. So,...and treat chemotherapy-related infertility via IVF embryo cryopreservation and embryo transfer after breast cancer," said Professor Oktay. "We exploited tamox...Wolf Prize shared by Texas A&M, Missouri researchers
... an array of proteins and mechanisms that regulate embryo development, fetal growth and immune competence. T...rified the biological mystery of signaling between embryo and mother to establish and maintain pregnancy." The two collaborated on the research for 16 years w...Insight into the genetic pathways that drive segmentation like clockwork
...nism and the role of the segmentation clock in the embryo remains a challenge for the future."...Scientists hone in on cause of amphibian deformities
...ially that caused by pesticide runoff, might cause embryo deformities or other problems. Laboratory tests suggest there may be some linkage, but field tests make it clear pesticide exposure can't be the sole cause of amphibian deformities. Parasites: A tiny trematode appears to cause a significant amount o...Umbilical cord matrix, a rich new stem cell source, study shows
...sels in the umbilical cord from compression. As an embryo forms, some very primitive cells migrate between the region where the umbilical cord forms and the embryo. Some primitive cells just might remain in the matrix later in gestation or still be there even after the baby is born. The K-State research t...