'Biomedical switch' regulates how cells stick together and communicates
...ose a model regulating cell adhesion -- central to embryonic development, cellular movement, and communication REHOVOT, Israel -- February 28, 2000 -- "Hard times," or more specifically, exposure to rigid environments, enhances the tendency of cells to form tight adhesions and communicate, according to a rec...Protein that stimulates blood vessel growth also helps repair broken bones
...is examining whether it might also be important in embryonic bone growth. They have begun injecting either VEGF or inhibitors of VEGF into the limbs of embryonic chickens as they develop in the egg. They will then examine the effects of too little or too much V...Gene tracking follows cells from embryo to adult
...low the migration of cells as they stream from the embryonic mouse brain to the developing body, including the ...ing structures. This is the first time a group of embryonic cells has been 'tagged" and followed throughout development to their final destiny. The research wa...White House honors Hutchinson Center Scientist with Presidential Early Career Award
... considered the zebrafish as a model of vertebrate embryonic development. Moens studies the zebrafish, she says...es cancer. Indeed, many of the genes necessary for embryonic development, which are meant to lie dormant during adulthood, are the same ones that later mutate an...Researchers seek clues to help newborns with abnormal lungs
...structural development of blood vessels during the embryonic stages when low levels of NO lead to vascular smoo...ment of the specific genes and proteins during the embryonic stages, these mechanisms cannot fully compensate for the existing defects and the babies suffer from...Mice unable to synthesize vitamin C should become valuable research tool, scientists say
...pecially designed DNA containingmodifications into embryonic stem cells of mice in tissue culture. The resulting genetically altered stem cells are injected into normal mouse embryos, which are then implanted in pregnant mice. "Chimeric" mice are soon born that transmit the altered gene to their own offspring.......ion factors to control the generation of different embryonic cell types, but there hasn't been strong evidence for this mechanism in mammalian systems. Now, researchers led by Singh, have shown that different concentrations of a single transcription factor, called PU.1, can cause blood cell progenitors to go d...$16.3M grant will fund program to develop mouse models for neurological research
...tagenesis technologies, such as treatment of mouse embryonic stem cells with chemical mutagens other than ENU, based on recent work by TJL Staff Scientist Dr. John Schimenti. These improvements will broaden the range of "target" genes and result in more efficient production of mutants. Hand-in-hand with the ...Adult stem cells can produce a wealth of cell types, Science authors report
...n adult neural stem cells from mice are grown with embryonic cells or within an embryo, the adult stem cells ca...ody of data indicating that adult stem cells, like embryonic stem cells, may be more versatile than previously assumed. Embryonic stem cells are the "blank slate...New research animals earn their stripes
...d component or which are the result of incomplete embryonic development. The scientific discoveries are likely to lead to many health benefits which, in turn, will open up huge commercial possibilities. "There is big money being invested by pharmaceutical companies in the genetic research done on zebrafish,...New developments in mouse genome biology
...lex, a genome region packed with genes involved in embryonic development. The mouse t-complex has long attracte... Most of these genes appear to be active in early embryonic development, suggesting that entire regions of the t-complex may turn on and off together as part of...Experiments point to new theory of skeletal development
...covered that the future uniqueness of each budding embryonic digit is determined by the webbed tissue located n...or of Anatomy. "The general thinking has been that embryonic cartilage, digits and limbs are self-differentiating systems that develop independently." Fallon an...Scientists map first structure in important family of proteins
...tand how GPCRs transduce the signals that regulate embryonic development and control the heart, blood vessels, synaptic traffic in the brain and, indeed, the functions of virtually every eukaryotic cell." While genomes have been rightfully getting a lot of attention lately, the proteins that the genomes produ...Biotechnology research to grow from embryonic start
...nology company, BresaGen, expects to receive human embryonic stem (ES) cells in the near future from the Univer...ction of Professor Peter Rathjen. Stem cells are embryonic cells, among the first to appear as a fertilised egg develops. They have the ability to develop int...Driving differentiation of human embryonic stem cells
...rowth factors have on the differentiation of human embryonic stem cells. According to the researchers, their ef...nt a step toward understanding how to direct human embryonic stem cells to become the more specialized cells that make up specific tissues such as brain and musc...Defining a niche that regulates stem cells
...e cells that govern the production of Drosophila embryonic germline stem cells - those cells in the ovary tha...ion appear to be conserved in Drosophila through embryonic and larval development. "This fact may simplify the problem of creating differentiated cells from st...Northwestern program aims at revealing genetic causes of spina bifida
...ults from improper closure of the neural tube, the embryonic structure from which the brain and spinal cord are formed. In the severe forms of spina bifida, part of the spinal cord is left uncovered by the skin and bone or actually protrudes from the spinal column. More severe forms of neural tube defect are o...Adult stem cell therapy for heart failure proves promising
...ibly replace dead heart muscle would be the use of embryonic stem cells. These early cells can differentiate i...y Chiu's group might offer an alternative to using embryonic stem cells. Also, because the marrow stromal cells come from the patient, there would be no rejecti...Cloning can turn back the developmental clock
...ggs ability to reprogram an adult cell back to its embryonic state and show for the first time that the process...n adult cell to a state that is appropriate for an embryonic one. "Scientists have suggested that cloning of mammals by nuclear transfer requires reprogramming...Press invitation: The science of stem cells - December symposium at Imperial College
...ofessor of Fertility Studies, Imperial College, on embryonic development Professor Sir Magdi Yacoub, BHF Profes...possibility of allowing scientists to derive human embryonic stem cells and specific cell lineages, e.g. bone, heart or brain. If this research is successful, it...