Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
... events that produces the disorders. "The brain is entirely dependenton glucose metabolism, and this is a protein that is important in that pathway,"he said. "But because GAPDH is expressed in every cell, not just inbrain cells, there has to be another level of complexity that we don't understand." "This is ......beenthought." To prove that the food web was based entirely on chemicalenergy and not solar energy, Kane, doctoral candidate SerbanSarbu and assistant professor Brian Kinkle used a technique knownas stable isotope ratio analysis (SIRA). This was the sametechnique used to demonstrate that the communities livin...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...the Sept. 6 issue of the journal Cell,describes an entirely new cellular signaling mechanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan directly activate genes. The work was funded by the National Heart,Lung and Blood Institute, a division of the National In...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
...the Sept. 6 issue of the journal Cell,describes an entirely new cellular signaling mechanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan directly activate genes. The work was funded by the National Heart,Lung and Blood Institute, a division of the National In...Researchers Identify A New Cellular Structure: The "Dumposome"
...component, dubbed a "dumposome," mayprove to be an entirely new organelle. It's introduced in the cover story of the October 4 issue of Cell . "The dumposome surrounds the DNA it's gobbling up, and then spits it out of the nucleus," says C. David Allis, theUniversity of Rochester professor of biology ...NIH Team Discovers Endocrine Tumor Gene
...ene. "This gene could indicate the presence of an entirely new pathway for the control of cell growth," says Dr. Collins. MEN1 is expressed throughout the body, not just in the endocrine glands as scientists might have predicted based on the endocrine tumors characteristic of the disease. The researchers say...Natural Variability Is Key To River Restoration
...River (New York): "Dammed, channelized and almost entirely controlled, the Mohawk River is now dominated by hearty, non-native species and recreational boats." Columbia River (Washington, Oregon): "Despite intense public interest, a major salmon industry and hundreds of millions of dollars annually devoted...3-D Structure Of HIV Components May Pave The Way For New Anti-AIDS Drugs
...HIVprotein may provide just that--the basis for an entirely new class of highlyspecific anti-AIDS drugs. Scientists working with support from NIH's National Institute of General MedicalSciences have determined the three-dimensional molecular structure of the HIVnucleocapsid protein bound to the virus' geneti...Washington University Licenses Its New Antibacterial Technology
...nology. The agreement will allow SIGAto develop an entirely new class of antibiotics that are less likely to besidelined by bacterial resistance than current therapies. It also provides threeyears of research funding to the Washington University scientists who areinvolved in this project. SIGA Pharma...Leftover Fetal Cells May Affect Development Of Scleroderma
...ion as to whether some autoimmune diseases are not entirely autoimmune,whether they actually have a component that is non-self. It's really anentirely new paradigm." Dr. Nelson says the mix of self and non-self cells, aphenomenon known as chimerism, is somewhat analagous to what happens in a personwho recei...Study Links Viruses And Vascular Diseases
...ink is stillinconclusive, but Virgin believes it's entirely possible that both viruses andbacteria might be capable of damaging blood vessels and triggering disease."It's highly unlikely that one single agent is the cause of all vasculardisease," he says. If viruses do in fact set the stage for atherosclerosi...Butterfly Wings, Beetle Horns Teach Biologists Basic Lesson In Development's Laws
...ol of how big an organ or tissue grows doesn't lie entirely within thatorgan or tissue," Nijhout said. "It has long been suspected that this is thecase, but the evidence has been indirect. For example, your arm may grow to acertain length because of some genetic development program within that arm. Butif you ...New Study Shows White Males Have More Receptors For Patent Blood-Vessel Contracting Substance
...s more bad news for white males. "We won't entirely know the relevance of this study until we do the sameexperiments with arterial tissue, but it's an important first step," saidDr.Adviye Ergul of the University of Georgia's department of biochemistry andmolecular biology. Collaborating with Ergul on ...The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
... of gigantic fruit fly sperm, which enters the egg entirely during fertilization, persist in the developing midgut of the embryo and are excreted soon after the larva hatches, reports Tim Karr , a developmental biologist at the University of Chicago, and Scott Pitnick, an evolutionary biologist at the Univer...Results Of Hog-Stress Study May Lead To Better Management Methods
...rollablein that applicable cooling systems are not entirely effective, and air-conditioningfor an entire pig facility is financially improbable, Johnson said. "Our data indicate that when the three stressors were imposed simultaneously,their detrimental effects to swine growth performance, in general, weread...Plants - Factories Of The Future
...that don't exist in nature, allowing us to produce entirely new products," said Dr Green, who added that there is still substantial work to be done before plants producing high levels of these fatty acids are widely available....Tiny Jamaican Tree Crab Made Big And Fast Evolutionary Leap, Scientists Discover
...ine crab that began evolving strategies for living entirely onthe land," he explains. The scientists also determined how closely each of the 22 species is related tothe others by comparing the molecular sequences that make up each of the twogenes and then determining which are most similar. "We found that ...Colorado State Research Indicates Two TB Vaccines Show Promise
...Colorado State and the other by the Merck Co., use entirely different approaches to fight tuberculosis. BCG isn't used in the United States because until recently, U.S. medical authorities expected TB to be eradicated early in the next century. Instead, the disease has become the leading bacterial killer i...Report Focuses On Managed Care Impact In Clinical Microbiology Labs
...iology, is the only honorific organization devoted entirely tomicrobiologists and the science of microbiology. The American Society forMicrobiology is the largest single life science society in the world, with over42,000 members representing a broad spectrum of disciplines in themicrobiological sciences, incl...... from about 30 towell over 200 atoms was therefore entirely unexpected." And yet the beetle pupae use very simple chemistry to produce these unusualcompounds. Three different small building blocks related to ordinary fatty acidsare used to assemble the rings. Many different combinations of the buildingblocks ...