RNAi delivery system crosses blood-brain barrier to target brain cancer
... portal in the blood brain barrier, and then gains entry into brain cancer cells with the second antibody t...ly to the transferrin receptor, the liposome gains entry to the chamber in which the brain is normally screened from pathogens, foreign proteins, and even sm...Nanoparticles illuminate brain tumors for days under MRI
...serves as a natural defense system by blocking the entry of foreign substances, including therapeutic agents. "Anytime there's an injury, it induces inflammation," Neuwelt said. Ferumoxtran-10 is "taken up by inflammatory cells in the brain. You can see them in stroke and MS, you can see them in tumors. Ga...Danger spots identified for threatened grizzly bear
...and translocation actions are reduced, the limited entry spring hunt--a controllable source of mortality--should be closed," he said....Mexican farmers effectively cultivate phenotypic diversity in maize
... be conserved isolated in reserves, protected from entry of other varieties from elsewhere and cultivated according to ancestral farming practices. Researchers from the IRD and the CIMMYT of Mexico (1) used work previously conducted in Mexico on maize varieties, or landraces, to devise a different, dynami...UCLA chemists develop new coating for nanoscale probes
...d quantum dots are small, they have easy and rapid entry through the cell membrane," Pinaud said. "In addition, since multiple peptides of various lengths and functions could be deposited on the same single quantum dot, we can easily envision the creation of 'smart' probes with multiple functions."...Rutgers ecologists and Brooklyn Botanic Garden botanists to plan Beijing Olympics Forest Park
...ogical and botanical components of the competition entry by Sasaki Associates, based in Boston, who coordinated the competition entry. In addition, the Tsinghua University Urban Planning and Design Institute in Beijing is part of the team, providing design and administrative functions. "The complex ecologi...Grant from GE Foundation to University of Houston to strengthen math, tech 'pipeline'
... "pipeline" are adequately prepared for successful entry in and completion of a university program in related subjects. GE volunteers from the Houston area will support the program by serving as student and teacher mentors using "customized" mentors who represent minority or female groups and providing...Purdue scientists finding ways to outsmart crop-damaging bugs
...nt binding of the chemical to the receptor and its entry into the bugs' system. Once this occurs, the chemical becomes ineffective and a new way to stop the insects is needed. Discovery of other toxins to attack insects that have the altered receptor offers a new way of minimizing resistance in the insect ...Tips from the Journals of the American Society for Microbiology
...urvival during pasteurization is the most probably entry route for the few NSLAB cells found in cheese during early ripening," say the researchers, who also tried to identify the mechanisms of heat resistance. "The results of this study show that the heat resistance of L. plantarum is a complex process wh...Preoperative treatment with Arimidex(TM) allows patients to undergo less extensive surgery
...noperable tumours or requiring mastectomy at study entry (n=344), less extensive surgery became feasible an...y became feasible in those requiring mastectomy at entry or any type of surgery became feasible in those with tumours previously considered inoperable. The n...New environmental journalism website holds more than 700 articles in three languages
...e website, journalists can access the rules and an entry form to submit their articles. The BDRA's international jury will use the site to review and evaluate the articles online. Once they are judged, the articles are made available to the general public and are added to the BDRA's growing database. The ...Researchers find a protein that controls cell growth
...rol cells with unmutated Skp2. The premature entry of a cell into the S phase is a potential cause of genetic instability, which in turn can propel a cell into uncontrolled proliferation, resulting in cancer. Dr. Pagano says that his laboratory plans to ascertain whether there are mutations in the ge...McGill scientists publish detailed picture of how nutrients and other molecules get into cells
...nents of the molecular machinery that controls the entry of nutrients and other molecules into cells. In a study published in the Proceedings of the National Academy of Sciences of the USA (PNAS), Dr. Peter McPherson and colleagues used proteomics, the large-scale study of proteins, to identify the protei...Migraine mouse provides insight into neurobiology of devastating headaches
...by weaker stimuli with consequent enhanced calcium entry into neurons, increased release of excitatory neurotransmitters, and increased susceptibility to cortical spreading depression (CSD), the phenomenon that underlies the migraine aura. "Previous studies have indicated that CSD is a wave of intense neur...Stanford study questions identity of alleged Romanov bones
...arities provided the original impetus for Knight's entry into the forensic debate. About three years ago, Daryl Litwin, an author of the Knight et al. paper who was studying law in Sacramento, proposed to Knight the idea for a re-analysis of the Gill-Ivanov data after reading Robert Massie's book The Roman...JCI table of contents, 16 February 2004
...d to inhibition of cyclin A expression and blocked entry into what is known as the S-phase of the cellular replication cycle. These studies identify a new target for intervention in the prevention of cardiovascular disease. TITLE: Antimitogenic effects of HDL and APOE mediated by Cox-2dependent IP activati...Passwords to guard entry aren't enough to protect complex data
Passwords to guard entry aren't enough to protect complex data - security mechanisms also must protect what goes out "Data can easily find itself in danger of being accessed by 'bad guys,'" says emeritus professor of computer science Gio Wiederhold, who will speak about trus...Scripps scientists say genetic mutation doesn't protect against HIV and plague
...D4+ T helper cells. HIV particles use CCR5 to gain entry into CD4+ T cells. The CCR5 32 mutation -- a deletion of 32 bases of DNA from the CCR5 gene -- was first identified in 1996 in individuals who seemed to be protected from infection with HIV despite having had multiple high-risk exposures to the viru......ibrio can remain encysted at this stage, while the entry pore has been sealed and the prey cell remains viable. Most commonly, however, Bdellovibrio immediately enters its growth phase in which it depends on the prey's amino acids. The amino acids and other nutrients are made available to the invader by th...... nucleus of nerve cells. There, it facilitates the entry of molecules into the nucleus along with its "sister" molecule, importin alpha. The scientists found that importin beta is produced in the axons upon injury. It then binds to importing alpha, which is normally present in axons, and to proteins that ...