Scientists discover role for Cdk4 in making cells cancer resistant
...of Cdk4 activity may provide an alternate point of entry for doctors to regulate the cell growth cycle and halt tumorigenesis....Scientists identify motor that powers parasitic cell invasion
...te host cells within 10 to 30 seconds. "This rapid entry process is essential for Apicomplexan parasites to replicate safely, hidden from the immune system," says Dr Soldati. Researchers established myosin A's function by knocking out the gene in Toxoplasma gondii and observing the effects on its motility....Revealed: How a master protein remodels chromosomes to orchestrate gene expression
...y which multiple chromatin remodeling factors find entry sites into chromatin," thereby providing "a mechanism for global gene regulation in higher eukaryotes." "SATB1 targets chromatin remodeling to regulate genes over long distances," by Dag Yasui, Masaru Miyano, Shutao Cai, Patrick Varga-Weisz, and T...New predictor of heart disease risk found
...er. "The attachment of white blood cells and their entry into the vessel wall are early events that lead to fatty streaks or early plaque formation." These novel findings at the molecular and cellular level support the work of other investigators who have shown that patients with increased levels of c-reac...Finding sheds new light into mysterious process of cell movement during development
...f this proves to be the case, then it provides "an entry point to elucidate the molecular basis of this class of neuronal migration," they conclude in the article....U.Va. researchers identify switching action by protein 'gate-keepers' in cell nucleus
... August 9 A switching mechanism that controls the entry of proteins into cell nuclei, where genetic materi...help the truck distinguish among different nuclear entry codes." The nucleus of a cell is surrounded by a wall that separates the DNA from the rest of the ce...New insights into insect antimicrobials point the way to novel antibiotics
...tches of the peptide that are responsible for cell entry are separate from the segments responsible for bacteria killing, the research team says that it might be possible to use an altered version of the peptide as a delivery vehicle for a variety of drugs into human cells, rather than solely as an antimic...Science, Amersham Biosciences announce call for applicants for 2002 Prize for young scientists
...ze, entrants must submit a 1,000-word essay and an entry form, which can be found at www.amershamscienceprize.org . Materials must be submitted in English, French, German, Spanish, Japanese, or Chinese (Mandarin). The deadline for entries is July 15, 2002....Gene found that controls stomatal cell growth in plants
...ide of leaves and control the entry of gases into the leaf for photosynthesis. Normally, stem cells - cells that are self-renewing and that form specific types of cells - in the Arabidopsis epidermis will divide asymmetric...NHGRI prioritizes model organisms for sequencing
...d the next group of organisms to be considered for entry into the sequencing pipeline as the current efforts with human, mouse and rat approach completion. The organisms designated as high priority for having their genome analyzed include chicken, chimpanzee, several species of fungi, a sea urchin, a micro...Mechanics of bacteriums toxin being unraveled
...roscope, accompanies the toxin during invasion and entry into a cell. The tool, she said, will allow researchers to test inhibitors or other blocking agents that might be developed to fight toxin-mediated infections. Wilson also discussed new findings from the May 3 issue of Circulation Research, in which ...A possible new way to block HIV infection of healthy cells discovered
...ntial mechanism of the interaction with HIV at the entry point of healthy cells, said Ziwei Huang, a professor of biochemistry at the University of Illinois at Urbana-Champaign. Huang was the principal investigator of the study, which appears in the May 17 issue of the Journal of Biological Chemistry. Hua...Study suggests mechanism for heart defect that kills young athletes
... for its expression. This finding provides a novel entry point for the researchers to explore what other factors might interact with this region to drive expression of TNNT2. While the animal is a superb model for teasing apart the function of different genes in the developing embryo, it cannot serve as a ...Experiments reveal ancient blood flow map
...tion. Instead, blood cells clumped together at the entry point into the tail region. The researchers concluded that without a functioning VEGF receptor, the blood cells could not find their way to their destination. How long-range migration of blood cells is accomplished has been an open question for a lon...Scientists solve first flavivirus structure
...f the dengue virus also suggests it employs a cell entry pathway similar to another group of viruses known as togaviruses, Kuhn says. The Purdue team is now pursuing experiments to determine how the virus puts itself together and how it carries out the fusion process with the host cell....A gateway for Ebola/Marburg viruses
...s are dependent upon cell membrane lipid rafts for entry into the cell and ultimately for virus assembly and budding, and are thus potential therapeutic targets. They further go on to demonstrate that virus-like particles (VLPs) that do not contain viral genome (and thus are of potential therapeutic utili...Information technology provides biologists with new tools for biodiversity conservation
...imulated research activity, says Wake. This single entry point to global data on amphibians is helping us develop a world view. AmphibiaWeb is helping scientists understand global amphibian species distributions, conservation status, the total number of species described, and rate of new species descriptio......its inner and outer layers and is initiated by the entry of sperm into an egg-is intimately linked to a pro...e report. "People have long known that the sperm's entry into the egg prompts these initial differences. But how the cell sets up these molecular differences...Study reveals new information on how viruses enter cells
... DNA into a host cell reveals a unique and complex entry scheme for viruses. The study may provide clues to how similar viruses infect cells and suggest ways for developing a new class of antibiotics and other drugs to prevent illnesses caused by viral pathogens. Scientists at Purdue University hav...Another transmembrane protein structure solved by Rockefeller scientists
...pecialized proteins that provide ports of cellular entry for potassium, sodium, calcium and chloride. MacKinnon, who is a Howard Hughes Medical Institute investigator, leads a scientific team that is adding unprecedented detail to existing descriptions of the chloride ion channel. The research findings ar...