NIDA, CSAT, CDC sponsor conference on drug use, HIV and hepatitis
...nfectious diseases among drug users, to facilitate entry of drug users into drug treatment, and to link them to appropriate medical care. The conference has the overall goal of advancing the integration of best practices in prevention, outreach, assessment, case management, medical treatment, and monitori...International trade imperils U.S. plants, animals and crops
... irradiated, this is not sufficient to prevent the entry of many harmful pathogens, D'Antonio said. "Nursery stock has really been bad news for U.S. forests," she said. The U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) is responsible for inspecting all imports fo...Research highlights from Pacific Northwest National Laboratory
...s comply with regulatory requirements, reduce data entry time and reduce waste through sharing and exchanging of materials. ETI offers CMS as part of an integrated laboratory management system....Study reveals family secret of how viruses enter cells
...iruses have developed ways to use them for gaining entry into cells. The CD155 receptor is made up of a single protein and is shaped somewhat like a leg divided into three sections, called domains, extending from a "hip" that penetrates the cellular membrane. Rossmann's group has determined that the vi...A relative of smallpox is first virus found to invade cells as HIV does
...a virus related to smallpox uses the same route of entry as HIV to invade its host. This is the first virus...us - evidence that each functioned as a binding or entry receptor for the virus. Other pathogens, including the malaria parasite and streptococcus bacteria...Scientists discover how cells 'catch' a cold
...us and HIV are very different, their mechanisms of entry into cells show some similarities,"Flanagan says. This may help scientists better understand how viruses evolve -- for example, how they change to evade the immune system while retaining their ability to bind to specific cell-surface receptors. The ...... many women in the LI group were at or below their entry weight as compared with the control group, which g..., the LI participants were 0.18 pounds below their entry weight at the end of the study, while controls had gained an average of 5.2 pounds. Likewise, end...AGU names new journalism award for David Perlman
...ls of the awards, eligibility requirements, and an entry form are available on the AGU web site [www.agu.org/sci_soc/prrl/sullperl.pdf]. Any member of AGU may make a nomination, and authors may nominate themselves. The next Sullivan and Perlman awards will be made in 2000 for work published in 1999 in any ...A 'Juliet' is found for the rare lemur Romeo
...e chambers with separateventilation systems and an entry area in which people can don isolation suits.The quarantine will also prove invaluable for isolating animals coming into thecenter from zoos and other facilities, according to Glander. Romeo first came to the Primate Center in fall 1993, alon...Seeing one weapon from a food-borne pathogen
...e, binds to receptors on Mcells. This leads to the entry of the bacteria into regional lymph nodes in theintestine. The growth of bacterial colonies in the lymph nodes triggers intensenausea, vomiting and diarrhea. It turns out that invasin is crucial to thebacterium's ability to establish a foothold in th...Scientists discover new candidate drugs for treating HIV infection
...HIV infection by stopping the virus at its port of entry into the cell. Unlikecurrently used drugs that ta... development of small-molecule drugs that stop HIV entry into cells," saysDr. Kim. "Alternately, scientists can use our 'pocket' to carry outhigh-throughput...New drugs target HIV's deep pocket
... team also showed that these molecules blocked HIV entry into cells. "Thesepeptides provide proof-of-principle that pocket-binding molecules can stop HIV,"Kim said. Kim hopes that drug companies will use this research to find morepocket-binding molecules. Toward this end, the Whitehead Institute is offeri...Bubonic plague kills by cutting off cellular communication
... a specific functionand they work together to gain entry into a cell and destroy the body's defensesystems. "In this study, we found that YopJ binds to similar molecules located at thesame point in two critical cellular signaling pathways," Dixon says. The first pathway, called MAPK, controls cell growth a...Research puts sting into drama of virus-cell fusion
... for the membrane fusionprocesses that lead to the entry of retroviruses and other viruses such asinfluenza...theCell, may lead to novel treatments to block the entry of retroviruses and othermembrane-possessing viruses, Sanders says. Sanders studies the structur...High HIV RNA levels major risk factor for mother-to-child HIV transmission
... of the 84 women who hadundetectable RNA levels at entry into the study and none of the 107 women whohad undetectable RNA levels at delivery transmitted HIV to their infants. However, transmission did occur at all levels of detectable RNA. Six percent ofinfants born to 395 women who had detectable levels ...HIV variant in U.S. and Europe found rare in Africa AIDS cases
...is known as V3. The virus uses this region to gain entry into thehost's T cells by way of cellular co-receptors known as CCR5. However, the cladeB HIV variant associated with rapid AIDS progression switches co-receptor usage- from CCR5 to CXCR4. (This switch lends the variant its name: X4) "V3 determines ......VCH, Weinheim. As every year the review and/or new entry of MAK values orthe classifications of numerous substances are announced in the "Yellow Pages"of the list of MAK and BAT values....Study: calcium channels regulate cell movement
...tocytes on silicone rubber sheets andmeasuring the entry of calcium ions into the cells in response to thestretching. During stretching, calcium concentrations inside the cells jumpedfor periods of three to five seconds, Lee said. Some calcium came from outsidethe cell, while the rest was released from int......f his research is to understand how pathogens gain entry tomammalian cell targets during disease processes. Dr. Ghosh's current researchon the mechanisms of host cell invasion by various pathogens promises toelucidate the process of infection and subsequently to identify specificcellular targets for drugs...Protein essential for making steroids turns out to be a "molten globule"
...unfolded. That may be because the ports that allow entry into mitochondria are very small,Bose said. "Think of a protein as a ball of spaghetti. It can only get into themitochondria one strand at a time." A section of the protein called the"mitochondrial leader" enters a port. Inside the mitochondria, im...