Chopping And Cooking Affect Garlic's Anti-Cancer Activity
...d"after chopping or crushing the garlic enables an enzyme naturally present incertain garlic cells to come i...rushing the garlic opens the cells and enables the enzyme tostart a reaction that produces chemicals called allyl sulfur compounds thatpossess anti-cancer pro...New Company Formed Through Licensing Of Cardiac-Hypertrophy Technology From Texas Institutions
... could prevent hypertrophy in mice by targetingthe enzyme calcineurin. At last week's American Heart Association meeting inDallas, Olson presented additional licensed discoveries that further elucidatethe molecular signals of heart enlargement. Independent sources have predictedthat this technology, though ...When Genes "Breed" In The Lab, A Suprising Number Of Their Offspring Are Supergenes
...eir DNA with ultrasound, or cuttingthem up with an enzyme called DNAse. They are reassembled into daughter genes,comprising fragments from several parents, using a variant of the DNA-buildingpolymerase chain reaction. Short template or "primer" sequences ensure that thefragments are stitched together in the...Duke Study Finds More Genes May Be Affected By Toxic Cadmium
...n response to stress; pyruvatecarboxylase, a liver enzyme that converts pyruvate to the sugar glucose; andmetallothione, which binds to the metal before it can damage cells. "When I originally set out doing this work, it just didn't seem to methat people had discovered all the genes that could be af...Scientists Describe Structure Of An Enzyme That Uses Iron To Make Hydrogen
The workings of an iron-laden bacterial enzyme could one day provideresearchers with an inexpensi... made a detailed description of the structureof an enzyme known as CpI, found in the soil microorganism Clostridiumpasteurianum. The results of their researc...Researchers Discover How Green Tea May Prevent Cancer
...nd that EGCg, a compound in green tea, inhibits an enzyme requiredfor cancer cell growth and can kill cultur...r independent studyhow green tea interacts with an enzyme on the surface of many types of cancercells including breast, prostate, colon and neuroblastoma. Thi...Clues To Molecular Cancer Switches Probed
...is in the promoter or control region thatturns the enzyme on and off. Brinckerhoff and her colleagues comp...lls, the team found. It's as if the switchfor the enzyme is always in the on position. Additional analysis determined thatthe difference was an inherited str...Champagne Gets Its Fizz From Tiny Acid Burns
... Acetazolamide blocks carbonic anhydrase, an enzyme which converts carbondioxide into carbonic acid. Carstens believes the sensation of "fizziness"depends on this reaction. "We think the carbonic anhydrase takes carbon dioxidegas, which dissolves in saliva then percolates through fatty tissue in theto...Immortalizing Enzyme Does Not Make Human Cells Cancerous
...oratory and immortalized bythe introduction of the enzyme telomerase are not transformed into cancer cells,p...ort pieces of deoxyribonucleic acid (DNA) that the enzyme telomeraseadds back to the tips of chromosomes - is the biological clock that governs howmany divisi...Experimental Therapy Makes HIV-Infected Cells Commit Suicide
...membranes. Then she attached two pieces of a human enzyme called caspase-3, which, when activated, enables cells to commit suicide -- this enzyme normally is kept under lock and key. She joined the three pieces together with cleavage sites from H......iver and protects the lungs frominjury by a common enzyme that normally fights bacteria and cleans up deadlung tissue. A person with A1AD does not generate enough of the protein toadequately protect the lungs, and permanent and irreversible damage results. Discovered in 1963, A1AD is often misdiagnosed as ...X-Ray Concentrator Will Expand Window On High-Energy Universe
... the protein's structure -- like the neuraminidase enzyme shown here --revealing where the atoms are located. From this, they can decipher thekey-and-lock structure and learn how to change how the protein works. However, the process takes many hours and dozens of crystallograms, partlybecause the X-rays are...How Super Are The "Super Aspirins"? -- New COX-2 Inhibitors May Elevate Cardiovascular Risk
...drugs, or NSAIDs. These drugs work by inhibitingan enzyme called cyclooxygenase, or COX. Scientists discovered early this decadethat there are two forms of the enzyme, COX-1 and COX-2, and that the first,COX-1, protects the lining of the stomach, while the second, COX-2, isresponsible for triggering pain an...Encouraging Results In Preclinical Studies Of Parkinson's Disease Gene Therapy
...are unable tomake tyrosine hydroxylase, a critical enzyme for dopamine synthesis in thebrain. These mice develop severe movement dysfunction that resembles that ofParkinson's disease patients. The mice also have behavioral defects and willnot eat and drink enough to survive without L-dopa therapy. Gene de...Researchers Determine Three Dimensional Structure Of Melatonin Producing Enzyme
...e determined the three-dimensional structure of an enzyme that produces melatonin--a key hormone that regula...ight promote wakefulness, and a drugpreventing the enzyme from being degraded might enhance sleep. Similarly, adrug that inhibits AA-NAT might provide a way ......opies of the gene, whose job it is to helpbuild an enzyme called ribonucleotide reductase (RR). RR is the o... gene for making a certain part of the critical RR enzyme inhumans. Without RR or RRM1, cells can't fix their DNA or reproduce. "Ribonucleotide reductase has...UCSF's Elizabeth Blackburn Receives Two Major Science Awards
...at UC Berkeley, Carol Greider, discoveredthe novel enzyme that creates telomeres. Telomeres play a curious...ent of some cancers. Blackburn's discovery of the enzyme telomerase hasspawned a whole field of inquiry into the possibility that the enzyme could bemanipula...... to Awad's groupthat suppressing the action of the enzyme might be useful in preventing prostatecancer in high-risk groups. The enzyme aromatase converts testosterone toestrogen, also considered a possible risk factor for prostate canc...Researchers isolate gene that helps plants take in iron from soil
...gues from the common weed Arabidopsis, produces an enzyme thattransforms ferric iron, the most common form o...d in soils, intoferrous iron. The ferric reductase enzyme straddles the surfaces of the plant'sroot cells in a series of loops. Each molecule of reductase co...Mechanism For Fungal Adherence Found, Possible Key To Disease
... to other proteins using an enzyme called transglutaminase. Theprotein ...or a mammalian enzyme. This enzyme is special since it can cross-link proteins together, two different proteins....