Tag: "errors" at biology news
No role for simian virus 40 in human pleural mesotheliomas
...archers to be vigilant in avoiding these technical errors
when planning future studies with SV40. "Because SV40 was a recognized contaminant of some polio and adenovirus vaccines in the 50's and early 60's, its potential to cause cancer in humans has been a source of intense debate since the apparent de...
How an insidious mutation fools DNA replication
...t detected and corrected, such a mismatch leads to errors
in the cell's machinery that can trigger the uncontrolled growth of cancer or the death of cells in aging. However, researchers have long known that the 8-oxoguanine-adenine mismatch seems to readily avoid detection by the polymerase. "There have bee...
Unicellular organisms contribute more nitrogen to ocean that reported earlier
...vative figures, according to the paper. First, any errors
in the researchers' experiment will tend to produce underestimates of the true rate, Montoya said. Second, they interpreted the data based on the assumption that unicells are only fixing nitrogen for 12 hours a day a common pattern for other nitroge...
In gene regulation, small is beautiful
...e or to stay quiet. Their role is crucial, because errors
in gene regulation can lead to diseases ranging from diabetes to cancer. Creating synthetic versions, known as artificial transcription factors or ATFs, could help scientists probe gene regulation and perhaps lead to new treatment approaches. Both na...
Medication reconciliation, pharmacist involvement vital to reducing medication errors, study finds
...tion and accurate dosage, the number of medication errors
dropped and with them the potential for patient injury. "A medication error, once in a patient's medical record, can carry-over from admission through discharge unless medication reconciliation is performed," says Kristine Gleason, who is on the hos...
Brain's reward circuitry revealed in procrastinating primates
...stant goal. They work more efficiently make fewer errors
as they get closer to being rewarded. But without...he same task, the monkeys made progressively fewer errors
with each trial as the reward approached, with the fewest occurring during the rewarded trial. Previ...
New diagnostic technology helps justify earlier cataract surgery
...sting can be used to accurately measure the visual errors
that show up as glare and other problems that cataract patients experience. This will give insurance companies a reliable and widely accepted means of testing for the effects of cataracts on patients' vision and for making reliable determinations of...
U of T research answers key question in biochemistry
...otein follows will also help scientists understand errors
in folding, a problem linked to diseases such as cystic fibrosis and Alzheimer's. ...
How DNA repair machinery is a 'Two-Way Street'
...hich guards cells against mutations by editing out errors
that occur during the process of chromosome replic...y of the cell. This machinery detects and corrects errors
in DNA replication in which the wrong DNA unit is stitched into place in a newly forming DNA strand....
Satellites map volcanic home of Africas endangered gorillas
...ing our knowledge to identify small classification errors
and other problems. The work is 95% done, with more to do on the other 5%. The new products will obviously be useful when it comes to co-ordinating patrols and associated activities. We now have one map extending across the three countries, while pre...
Fox Chase Cancer Center's Alfred Knudson Jr. named 2004 Kyoto Prize winner
...now-confirmed theory has advanced understanding of errors
in the genetic program that turn normal cells into cancer cells. Knudson's powerful insights into the development of cancer hold implications for both treatment and prevention. Tumor-suppressor genes, in particular, are important targets for prevent...
Published research contains 'high level of statistical errors'
...high publication pressure," write the authors. The errors
seen could have been caused by transcription or ty...8 to 2.5 rather than 2.4. "Although these kinds of errors
may leave the conclusions of a study unchanged, they are indicative of poor practice," say the resea...
Fat fighting undermined by over active eating pacemaker
...e had previously thought. Any number of a range of errors
could lead to over activity of these pacemaker cells and explain why many people find difficulty in eating less. In the research, published in the May Issue of Nature Neuroscience, Dr David Spanswick and his research team in the University of Warwick...
Uncertainty in clinical tests raises health care costs
...nic (Rochester, Minn.), estimates that calibration errors
in measurements of calcium levels in blood may add...nt of calcium laboratory tests contain calibration errors
of between 0.1 and 0.5 mg per dL. This means that some results that fall in the center of the "norma...
Genome-wide screen reveals new tricks of old genes
...ncer in humans. No one knows exactly at what point errors
enter the genetic material and aren't fixed, but the intricacies of chromosomes' manipulation during cell division seem a good place to start. Postdoctoral fellow Cheryl Warren, Ph.D., started the search by screening 5,916 yeast genes -- all at once...
Awards honor Alt's three decades of genetic cancer research
...t risk for mutations due to environmental insults, errors
in gene replication, and other factors that can ca...Again as with VDJ recombination, Alt believes that errors
in the "pasting" part of the process may lead to translocations and oncogene (cancer gene) activatio...
UCSF finding advances insight into adult stem cells in human brain
...ell developing genetic errors. The accumulation of errors
would make a cell more likely to slip into disregulated replication overdrive, the hallmark of cancer. "If this theory proves true," says Sanai, "it would open up a whole new avenue in brain tumor research." Building on previous research ...
Immune system's attack dogs kept on genetic leash
...ry contributing factor." Peng notes, though, that errors
in regulatory genes are unlikely to be the sole cause of a particular autoimmune disorder. "You probably need multiple malfunctions in different genes to cause a severe autoimmune syndrome," he explains. The Lupus Foundation of America estimates ab...
Resilience through improvisation
...ge." True, when DNA polymerase improvises a tune, errors
(i.e. mutations) may occur in the new cells' DNA. Yet Livneh explains that the body cannot feasibly let all cells with damaged DNA die, for there are too many of them. "Only if the DNA contains a very high level of damage will the cell's machinery 'g...
Online calculator improves analysis of chemical data
...to study the functions of proteins; and eliminates errors
or bias that might be introduced by manually translating mass spectrometry peaks into final chemical results. For example, by using Mass Spectator's automated calculations, law enforcement agencies can increase confidence in chemical analyses conduct...
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