Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...nathan Stamler in an interview."Oxygen delivery is essential to life and a deficiency in oxygen isassociated with diseases of every organ. The same picture is gradually emergingfor nitric oxide (NO). Understanding delivery of both in concert could haveprofound therapeutic implications. "The duet of he......alfunction in the body's regulation ofdopamine, an essential messenger of the nervous system. Neurotransmitter.... "Our results show the transporter is absolutely essential for amphetaminedependent transport of free dopamine into the synaptic space, to the exclusionof any ...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...chains in our model are intertwined, it is essential for them to untwist if they are to separate.... Although it is difficult at the moment to see how these processes occur without everything getting tangled, we do not feel that this objection will be insuperable." ...Heat-loving Microbe Repairs Its DNA With Light
...t itself. "Since the precise structure of DNA is essential for life and reproduction, it would seem logical that the S. acidocaldarius cell should have particularly effective ways of repairing damageto its DNA," said Grogan. Grogan tested the microbe's repair capabilities by artificiallydamaging the DNA of...New Discovery About Genes Has Implications For Genetic Therapy
...s are basically long strands of DNA that carry the essential genetic information needed to produce a protein. Scientists believed that only certain DNA sequences -- called exons -- carried useful information. Other pieces of "junk DNA" called introns are interspersed as "spacers" between the exons along the ...International Research Team Clones New Skin Cancer Gene
...ence is on the rise. The new gene, called PTC, is essential for keeping skin cells under control. "Genetic mutation of PTC is the key step in development of skin cancer,2 said Allen Bale, M.D., senior author of the Cell paper and director of the Cancer Genetics Program at the Yale Cancer Center. The discover...Researchers Use Hydrated Lime To Reduce Toxic Selenium Emissions
... byproducts producedby coal-fired power plants. An essential trace element for humansand other animals, large quantities of selenium can cause infertilityand damage to the liver, kidneys and lungs. About 2,500 tons of selenium are discharged into the atmosphereeach year in the United States alone. Regulations ...Researchers Find Possible New Route to Making Cancer Cells Vulnerable
...ate protein, called FKBP12,which they showed is an essential activator for the pump to work correctly.In other words, the two drugs primarily halt the cellular pump by removinga vital part, like a valve from a car's fuel pump. "Cyclosporin-related drugs are now being tested for their ability toreverse chemoth...Low-Protein Diet May Reverse Kidney Disease
...hers put 16 adults on a very low protein diet with essential amino acid or ketoacid supplements for 10 months. Essential amino acids are those amino acids -- building blocks of protein -- that the body can not make. Ketoacids are slightly modified forms of amino acids. The disorder gradually disappeared during...Discovery Of Cell Sites May Shed Light On How Bodily Systems Interact
...tuitary gland, located at the base of the brain,is essential for the body's resistance to bacteria. But the possibilitythat the pituitary gland may actually receive the message of illness anddirectly issue response orders, offers a new window for research, Kelleysaid. The mission now, he added, is to determine...Newly Discovered Gene Halts Cell Division and May Have Cancer Link
...zra says. The MAD2 checkpoint appears to plays an essential role in the cell cycle, Dr. Benezra says. After a cell's DNA is copied, each pair of the duplicated chromosomes is bound together at structures, called centromeres, that fit around each chromosome like a napkin ring. In order for a cell to divide, th...Scientists Identify Gene For Sexual Behavior In Male Flies
...ker realized that each of theirgroups had half the essential information needed to clone and understandthe role of the fru gene. "We had a map, and they knew where thecrucial point in the map was," Wasserman said. "To go on and understandhow the gene works called for the skills of the other two labs as well....World's Experts Plan Global Locator Service For Environmental Information
...iative will make use of base standards that are so essential for people to find the environmental data and information they need." The agreement was reached among representatives to the Global Information Society initiative, which was convened at the suggestion of Vice President Gore and organized by ...A Sensor, A Switch, A Zipper: Protein Engineers Design Potential Tool
... are found in hundreds of proteins and are essential to processes as diverse as gene transcription, muscle contraction, viral attack, and cell division. Please acknowledge partial funding for this work from the National Institute of General Medical Sciences (NIGMS), a ...Proteins Interacting With RNA And DNA Are Surprisingly Similar
...l the host," he said. RNA, or ribonucleic acid, is essential in the manufacture ofproteins rangingfrom vital enzymes and hormones to hemoglobin and structuralcomponents. DNA,or deoxyribonucleic acid, contains the huge library of geneticinformationorganisms need to reproduce and to make RNA. Both RNA and DNA ar...Selenium Supplements Can Reduce Cancer Rates
...in selenium and are balanced with respect to other essential nutrients. The most important dietary sources of ...areas. Of the 40 nutrients currently recognized as essential for human nutrition, selenium was the last to be recognized in 1957. A key component for at least t...Bigger Biology Tackled Through Keyboards
...ct's blueprint, such modelsaim to capture only the essential elements of a complicated phenomenon ina form that can be manipulated, investigated and used as an experimentaltool itself. "The art of modeling is knowing what to leave out," said Hastings,who recently helped bring to campus a research training gra...Ten Years of Progress For Superfund Basic Research Program
...s.Chromium is a similar case where Chromium III is essential tolife, and chromium VI is toxic." Caruso's research group published a paper last summer in theJournal of Analytical Atomic Spectrometry describing the methodsused to detect sub-nanogram levels of organotin compounds intheir gaseous form. His researc...High Levels of Vitamin C Prove Toxic to HIV
... to counter the AIDS virus, he added. Vitamin C is essential to the human body and is necessary for normal function of the immune system. The researchers studied vitamin C uptake and its effects on AIDS-virus production inHIV-infected and healthy immune cells, after finding in previous studies that cancer c...Eating After Exertion May Be A Key To Speeding Body's Recovery
...chemistry, specifically theratio of tryptophan, an essential amino acid, to large neutral amino acids,said principal investigator Donald K. Layman, a U. of I. professor of nutrition.Tryptophan levels in the blood help regulate the release of serotonin inthe brain, causing lethargy and fatigue. "The oat-based ...