Tag: "excessive" at biology news

New treatment for difficult-to-treat inflammatory disease

...inflammation-causing white blood cell, increase to excessive levels in the blood. The cells accumulate throughout the body and unleash powerful chemicals that can damage many different organs, including the heart, nervous system, skin, kidneys and digestive tract. Grantees of the National Institute of Allerg...

Researchers uncover biochemical connection between high-fat diets and increased colon-cancer risk

... hypercalcemia, a toxic condition that occurs with excessive calcium buildup. Mangelsdorf said the bodys natural lithocholic acid-response mechanism simply wasnt built to handle the amount of fat in the modern American diet. Our bodies can handle slight changes in lithocholic acid that come from a normal diet,...

Protein causes muscle wasting syndrome in mice

...rictor of muscle growth in animals now report that excessive amounts of the protein in mice cause rapid and dramatic loss of both muscle and fat, without affecting appetite. The results, obtained by implanting cells engineered to make extra myostatin into adult mice, support the idea of targeting myostatin to...

Research shows older children, adolescents grew heavier in Brazil, China, U.S. over past 30 years

...adolescents ages 10 to 18." Between 1971 and 1997, excessive weight tripled as a percentage of all children and...vity. Previous studies documented the increases in excessive weight among adults, and recently, two comprehensive investigations examined obesity in preschool ch...

Discovery sheds light on mechanisms that allow cells to steer directly toward chemical cues

...s and injuries that take longer to heal because of excessive inflammation. "When we have a site of inflammation or an arthritic attack, white blood cells rush to these sites just as they would to the site of an infection," explains Firtel. "But in this instance, instead of fighting a bacterial infection, the ...

UF researchers discover blood stem cells

...iry for scientists scrutinizing diseases involving excessive blood vessel growth, diseased arteries or other circulatory troubles. Doctors might someday be able to use the knowledge to encourage growth of new blood vessels that could repair injured organs or tissues or, alternatively, stop such growth when it ...

Cocaine use in warm environments impairs body's cooling mechanisms -- and can be lethal

...increase skin-blood flow, to sweat and to perceive excessive heat stress. The findings appear in today's issue of Annals of Internal Medicine. "Individuals who abuse cocaine, especially in hot temperatures while participating in recreational sports or attending rave parties, won't perceive that they are hot an...

Research into rare disease leads to discovery of six new breast cancer-susceptibility genes

...tched on. When a cell's DNA is damaged whether by excessive sunlight, chemicals such as those found in cigarette smoke, radiation, or other means five of the Fanconi genes team up to produce a protein "complex" that stimulates a sixth gene. That gene, dubbed D2, orders production of a protein that moves near...

Elevated levels of cholesterol play an even greater role in development of Alzheimer's, study shows

... breaks new ground in showing the damage caused by excessive levels of cholesterol." Papadopoulos added that many years of further study are required before any therapy derived from his team's findings might be tested in humans....

Society for Women's Health Research News Service to provide series on women and pharmacology

...removed from the market in recent years because of excessive harm to women," said Raymond Woosley, MD, PhD, dean of the College of Medicine at the University of Arizona. The Institute of Medicine explored therapeutic interventions in their May 2001 report, Exploring the Biological Contributions to Human Healt...

Weizmann Institute scientists win global competition in predicting protein-protein interactions

...teins approach one another a delicate task, since excessive modification can destroy the unique surface features of the original molecules. The CAPRI Challenge provides a service to the scientific community by establishing identical criteria for the comparison of different docking approaches. Independent gro...

New cholesterol disorder discovered As predicted from gene's role

...ol to bile acids is blocked. The liver responds to excessive cholesterol by reducing the amount of receptors available to take up low density lipoprotein, or LDL, -- the "bad" cholesterol from the blood. A mutation in the gene, they reasoned, would result in an accumulation of LDL. The team also predicted hig...

Nerve cells' death different from other cells'

.... Made in nerve cells' mitochondria in response to excessive DNA damage and PARP activation, AIF is sent into the nucleus, immediately causing the cells' genetic material to collapse. "AIF entering the nucleus seems to be the point of no return -- once it gets in, the cell is going to die no matter what you ...

Surprise, surprise, surprise: Hopkins scientists unexpectedly create epilepsy in rats

...mate into GABA-producing neurons may help calm the excessive electrical firing of brain cells, says Rothstein. In rats, the glutamate transporter EAAC1 is the main mover, getting the molecule into and out of brain cells and maintaining the appropriate levels of the excitatory chemical. By giving the rats pie...

Without blue crabs, southern salt marshes wash away, study finds

..., mainly from farms and lawns. The nutrients cause excessive aquatic plant growth. Resulting bacteria consume oxygen, especially during warmer months, eventually strangling fish and other species. "This research further suggests that human population growth and eutrophication may accelerate marsh die-offs that...

New enzyme pathway to nerve cell death discovered in stroke and neurodegenerative diseases

... work gives us a new way to think about preventing excessive activity of MMP enzymes, and as such it could lead to new therapies for stroke and several neurodegenerative diseases," said Lipton. This discovery was borne of an inter-disciplinary collaboration at The Burnham Institute making use of expertise on t...

Study identifies hypertension patients who can benefit from the little used diuretic amiloride

... If this control of this mechanism is not precise, excessive salt and water can be reabsorbed, leading to elevation of blood pressure. The high prevalence of high blood pressure that tends to run in African Americans families, and the discovery of mutations in the main protein responsible for this specific sa...

Additive that makes juices 'tart' quadruples yield of essential hemophilia treatment

...ors to raise their levels in the blood and prevent excessive bleeding," Shanbrom said. "But current methods of ...t known genetic bleeding disorder and is marked by excessive bleeding, inadequate blood clotting and, in severe cases, irreversible joint damage and life-threate...

MIT team probes arsenic and old lakes

...ch is also associated with noxious impacts such as excessive algal growth, was found to have a mitigating effect. It reacts with naturally occurring iron to create iron oxides that in turn adsorb arsenic. "The result is a suppression of seasonal arsenic release into the water," said Hemond, who is director of ...

Flexible joints associated with chronic fatigue syndrome, researchers find

...thostatic intolerance, a condition associated with excessive pooling of blood that results in heart and blood pressure problems, headaches, dizziness and other symptoms. Rowe and colleagues had previously reported that patients with orthostatic intolerance also have Ehlers-Danlos syndrome, a connective tissue ...

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