Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...nd Spinocerebellar atrophy I -- that have the same expanded CAGrepeat. "Traditional dogma is that mutant genes produce proteins that eitherdon't work at all or don't work well," said Burke, the first author."However, we found the proteins produced by these genes interact ina different way, based on the numbe...NCAR Scientist Models Earth's Climate and Vegetation Patterns At Last Glacial Peak
...laced by needle-leaf deciduous larches. The Sahara expanded southward as the Asian monsoon weakened and drier conditions prevailed across Africa and Southest Asia. Felzer checked his results against earlier LGM vegetation scenarios based on data from fossilized pollen retrieved from lake cores. His simulated ......rm operation andmaintenance of the majority of the expanded and upgraded global network aswell as for analysis, interpretation, and dissemination of the collecteddata to help verify compliance with the treaty. The data and network willalso be used for scientific and disaster-assistance purposes such asdeterm...Ten Years of Progress For Superfund Basic Research Program
...ds intheir gaseous form. His research is now being expanded to includeliquid samples and solid samples, which would be useful inanalyzing contaminated waters and harbor sediments. Working at very low levels of detection is important for anumber of reasons. First, many metals are toxic at very smallquantities....A Drug Pump On A Computer Chip
...rated circuit fabrication techniques, has recently expanded into the medical device market. "No company wants to build hospital infusion pumps any longer, since the whole health care system is striving to keep people out of hospitals," Huff said. "Drug delivery systems should be based on ambulatory deliv...Enzymes Targeted As Key To Understanding Drug Interactions
...ansten and Dr. John Horn have recently authored an expanded version of their book, Drug Interactions: Analysis and Management, to help health care professionals manage potential drug interactions in their patients. "There has been much publicity on the bad news about drug interactions," Levy said, "but this ...New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...enerations,she said. Eubanks is now embarked in an expanded study of the complex geneticrelationships between teosinte, Tripsacum , primitive corns and otherrelated New World grasses. The National Science Foundation's Small Business Innovation in Researchprogram is funding Eubanks' research on corn rootworm...STS-89 Will Carry Five Science Payloads From NASA/Marshall
...S-89,it will make twice as many test runs under an expanded range of conditions.It compresses a column of sand contained in a latex sleeve within a water-filledplastic case. "MGM is a very interesting science experiment that may have greatramifications for down-to-Earth engineering in the future," Kearnssaid...Emory University Fragile X Group Receives NIH Program Grant
...il the gene was discovered and theinfluence of the expanded CGG repeat was found to be responsible for the effect. Despite these significant breakthroughs, key questions about fragile X remain unanswered. The new grant will use novel genetic, molecular biological,neurobiological and biochemical appro...Good Ergonomics Is Good Economics
...mputer model for back compression was modified and expanded for easy application to the railroad environment and packaged by the Association of American Railroads. The AAR-Back Model was introduced at the Palistine Car Shop to identify job tasks that exceeded acceptable back compression values, and equipment ...New Sensor Will Detech Chemical And Biological Pathogens At Incredibly Small Doses
... biosensor. To develop the new biosensor, Velandar expanded upon some of his previous work. He adapted a technology he invented that is employed to purify pharmaceuticalspresent in blood plasma at trace levels. By combining his scientific processwith an optical fiber sensing device, Velander and Murphy have f...Desert Researcher Receives Environmental Award
...h hotand cold deserts of the world. The discovery expanded what was formerlyconceived of as the limits of life on the planet. He discovered that somemicrobiota were hidden from view under the surficial crusts of porous rocks. Prior to his work, it was commonly thought was that there were no growingmicroorga...Study At UNC-CH Shows Chlorinated Water Dramatically Cuts Strawberry Contamination
... "We believe that this research needs to be expanded to determinechlorination efficiency against other disease-causing organisms like Salmonellabacteria and other viruses and to other types of produce such as tomatoes andapples," he said. The Clorox Co. and Ramsey-SIAS, an agricultural processi...Engineered Neo-Organs For Bladder Replacement
...ium, plus smooth muscle cells. The cells had been expanded separately from a previously harvested autologous bladder biopsy. The researchers performed preoperative and postoperative urinary flow and X-ray studies. After their initial operation and recovery, the animals were sacrificed at 1,2,3,4,6 and 11 m...New Tests Demonstrate MuchLarger, More Specific Immune Responses To Viruses
...er of CD8+ Tcells. "It is likely that most of the expanded CD8+ T cells in these infectionsare specific to those particular viruses also," he says. Dr. Altman's initial findings have confirmed this prediction for HIVinfection and he continues to actively pursue investigations of the CD8 T cell...Georgia Scientists Study Salt Marsh To Understand Global Warming
...em. The utility of the data being collected can be expanded well beyond theparticular habitat at Sapelo where the study is under way. Theresearchers point out that the knowledge gained about the salt marsh canbe extended to other natural systems. Such information will be usefulas scientists grapple with the...Report Focuses On Managed Care Impact In Clinical Microbiology Labs
... In addition, as technologies and information have expanded beyond theknowledge base of the clinical user, the consultative role of the clinicalmicrobiologist has become increasingly more important, the report says. "Theclinical microbiologist is in the best position to give advice on the availableprocedures...First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
...rica, Inc., forcommercializationand to test it for expanded uses. The investigators anticipate that due to similarities between developmentin mammals the technique will be applicable to larger animals. For example,efficient and accurate cloning can improve the reliability and safety ofreproducing transgenic ...... the dorsal neural tissue and found that most ofit expanded and took over the ventral side," says Mullins. "Th...d after a popularswirled cinnamon pastry) shows an expanded growth of the neural crest, whereasin the swirl mutant it's absent. The swirl and somitabun genes ha...Forecasting The El Niño-Driven Ebb And Flow Of A Rogue Mosquito
...t is the principal carrier of the dengue virus,has expanded its range from its primordial home in Africa to mo...evalent in nearly 100 countries. Aedes aegypti has expanded its range in recent years to reinfest many parts ofthe Americas, areas where it was thought to have ...