Gene differences may alter susceptibility to multiple sclerosis
...for the development of an MS-like disease in mice, experimental autoimmune encephalomyelitis. Mice missing the protein did not develop the disease. For the present study, Liu and colleagues investigated whether CD24 was associated with the human disease by studying the two versions of the gene represented by the ......on in 1987. A ten-year period as a C4 professor in experimental physics at Augsburg was followed by his return to Gttingen for a similar professorship in 1999. He has worked on several long-term projects at the California Institute of Technology. Prof. Dr. Manfred Strecker (48), Geosciences, University of Potsd...Tips from the Journals of the American Society for Microbiology
...te or lead compound for exploring its potential in experimental systems for treating systemic bacterial infections." (S. Sharma, T.N.C. Ramya, A. Surolia, N. Surolia. 2003. Triclosan as a systemic antibacterial agent in a mouse model of acute bacterial challenge. Antimicrobial Agents and Chemotherapy, 47. 12: ...2nd Annual CDB Symposium: Developmental Remodeling (March 29 - 31, 2004; Kobe, Japan)
...lation at the level of chromatin organization, and experimental approaches to the recapitulation of pluripotency in somatic nuclei. These will be followed by sessions on the plasticity of cells and tissues in morphogenetic processes in development and regeneration following injury. The final session will address ......e detection, studied how this protein worked in an experimental cell system. She found that the protein acts like a gated bridge on the cell's membrane, connecting the inside and outside of the cell. The gate opened when the researchers added calcium ions. In general, proteins like TRPM5 are considered good p...Little-studied waves in the heart may be cause of defibrillation failure
...re studies to determine if the waves created under experimental conditions also occur spontaneously following defibrillation. Future studies based on this research will be conducted to better understand how to manage these waves, the effect of anti-arrhythmic drugs on them, and whether these findings could be us...Novel approaches to current cellular therapies continue progress toward disease prevention
...as somatic cell nuclear transfer, which is used in experimental tissue and organ generation, has recently been explored as a possible treatment for a wide range of degenerative diseases. A study led by Malcom A.S. Moore, D. Phil., Memorial Sloan-Kettering Cancer Center, New York, used the therapeutic cloning tec...Link between alcohol consumption and muscle damage in females
...jected with identical volumes of 0.15 mM NaCl. The experimental procedure involved intraperitoneal injection "pret... significant effect on Bcl-2 mRNA in any of the experimental conditions. Conclusions Alcohol acutely increases c-myc mRNA in skeletal muscle, possibly refle...Max Planck Research awards 2003 presented
...ersity in Montreal, Canada for his theoretical and experimental methods, with which he can predict the foundation properties of structures, such as for the frost heave of a pipeline built on permanently frozen soil. Two scientists were awarded the Max Planck Research Award 2003 in Mathematics: - Prof. Stephan Lu......cular structures are determined by the most modern experimental methods, including X-ray crystallography, NMR spectroscopy and cryoelectron microscopy. The Research Collaboratory for Structural Bioinformatics (RCSB), of which Rutgers is a member; the Macromolecular Structure Database at the European Bioinformatic...Scientists report on promising new approaches to induce cancer cell suicide
...Abstract 709 Researchers have shown that a new and experimental drug ZD6474 -- strongly inhibited the growth of three deadly brain tumors in animals. In the study, conducted at Duke University Medical Center, ZD6474 inhibited the growth of three types of human tumors grown in mice -- glioblastoma, medulloblasto...Three molecular-targeted compounds show promise against cancers
...ancies incorporating PET imaging: Abstract 663 An experimental pill aimed at several important signaling molecule... in their disease when offered the pill form of an experimental compound that alters certain genetic patterns of cells. Researchers at Memorial Sloan Kettering Canc...Physics tip sheet #39 - Nov. 17, 2003
...e distribution of fragments, and show that it fits experimental data for both of these very different systems. Many other natural phenomena could also be described by the same processes. Journal article: Available to journalists on request 4) Air bubbles slow sound waves in water. A. Krokhin, J. Arriaga, and L....Bush Administration plan to reduce global warming could devastate sea life
...at while the Administration's plan is still in the experimental stage, enough is already known about the biology of marine organisms to say with certainty that the plan will harm the marine environment in significant ways. Increased CO2 in the oceans would result in decreases in the pH levels (the measure of aci...Investigational cancer drug prevents abnormal brain growth, reverses seizures in lab mice
...s at St. Jude Children's Research Hospital used an experimental anti-cancer drug to prevent or reverse abnormal brain cell growth that is caused by lack of the anti-cancer gene Pten. The study demonstrated that the runaway cell growth in the absence of Pten is triggered by a second gene called mTor. The anti-can...With flu season coming, don't forgetexercise?
...stered. This strain in the mouse is an established experimental model of respiratory infection; this route was chosen to mimic the typical route of entry for viral infection. On the day of the experiment mice (n=24 per group) were exposed to either control treatment or exercise for one hour and immediately return...Herpes research uncovers possible clue to Alzheimer's disease
... Bearer, who holds both an M.D. and a Ph.D., is an experimental pathologist. DeGiorgis, who earned his Ph.D. in Bearer's lab last year, is now with the National Institutes of Health. Experiments in this study were conducted in the giant axon of squid, a model widely used in research because with a diameter of ne...Anti-platelet drug blocks bone metastases in mice
...gnant tumor in mice by disabling platelets with an experimental drug. Based on earlier experiments, scientists had...bones that produces blood cells." In contrast, the experimental mice lacking the beta3 integrin developed tumors in other parts of the body but had no tumor cells i...Salk news: Gene chips and crop yield
...entists now are taking the next step; using direct experimental methods to determine whether the computerized estimates were correct. "By putting the entire genome on gene chips, we found that the computers were wrong about a third of the time in identifying genes," said Ecker. "But we also found other genes we ...High school students to analyze plant genes for national project
... year will focus on working out the procedures for experimental design and developing and testing related educatio...ide wild-type and "knock-out" mutant seeds as well experimental know-how to the students. The "knock-out" seeds will have specific genes removed or inactivated. The...