16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
...pring and the "spring properties" of muscle can be exploited clinically. 24.4 Rainer P. Hambrecht (Heart Center, Leipzig, Germany)Effects of exercise training on vascular function and myocardial perfusion. Since the degree of coronary endothelial dysfunction has been identified as a predictor of cardiac eve...A novel, safer strategy for regulating gene expression
...rate that this natural system could be adapted and exploited to treat human disease....Scientists explore genome of methane-breathing microbe
...ve made a home in the genome. Such phages could be exploited to genetically manipulate M. capsulatus to more efficiently produce microbial protein for commercial animal feed. The study's senior author, TIGR Investigator Jonathan Eisen, says the analysis of M. capsulatus also will help scientists learn more ab...JGI announces community sequencing program portfolio
...nts of phosphorus inside its cell. Engineers have exploited this capability to remove excess phosphorus--from fertilizers and detergents--from wastewater. Too much phosphorous can over-stimulate microbial growth resulting in eutrophication, where oxygen in the water is depleted and fish and other organisms re...New mechanism for display of foreign proteins to immune system
...em identifies potentially harmful cells and may be exploited for future development of more effective vaccines. It is well established that the immune system has sentinel cells whose job it is to report the presence of foreign invaders or cancers. In a process called crosspresentation, the sentinel cell intern...Biologists ID defense mechanism of leading fungal pathogen
...a, the most common human fungal pathogen, could be exploited with new drugs for both lethal and non-lethal Cand...cks NO, in hopes of finding a weakness that can be exploited with drugs. In addition to Candida, Gustin's group is also interested in finding out whether other f...Volcanic soils yield new clues about the emergence of powerful chiefdoms in Hawaii
...covered by thick tropical forest, and successfully exploited them for hundreds of years. "The public perception of the early Polynesians focuses on their greatness as navigators and they were the greatest navigators of their era," said Peter Vitousek, a professor of biological sciences at Stanford Universit...Learned social preference in zebrafish
...f loose social aggregates, called shoals, and they exploited the developmental genetic resources of this biomedical model organism to manipulate the appearance of the fish. Fish were chosen to have drastically different color patterns, either blue and gold stripes or an absence of stripes and a uniform mother-...... of the vehicle's motion. This capability could be exploited both by autonomous military and commercial systems that require highly precise movement control....Ancient Greeks help scientists build environmentally friendly nano devices
...rior catalytic properties this is currently being exploited to make cheap greenhouse gas sensors. Growing magnets inside these nano-honeycombs produces nano-materials whose magnetic properties can be adapted for new generations of magnetic memories on a chip. The nano-scaffolds are being investigated for asse...Cross-species comparison reveals shared features between tumorigenesis and organogenesis
...pted developmental programs. "These findings have exploited our ability to analyze thousands of independently segregating genetic markers to confirm the classic proposals by investigators such as Lobstein and Cohnheim in the 19th century that tumorigenesis recapitulates aspects of development," Rowitch said. ...Dana-Farber scientists discover natural blocker of HIV-1 virus
...similar molecule known to exist in humans might be exploited for prevention and therapy. Named TRIM5-alpha, the blocking molecule may be the first example of an innate, previously unknown arm of the immune system that patrols the body for viruses and, if they enter a cell, prevents them from causing harm. "T...Protein abundant in human tumors confers resistance to anticancer drugs
...st apoptosis during stress-induced repair could be exploited by human tumors to survive under adverse conditions. In addition, because MUC1 reduces the normal apoptotic response to DNA damaging agents, it is an attractive target for design of future cancer therapeutics," explains Dr. Kufe. ...Navy enlists microbes to cut costs
Microbes have been exploited for thousands of years to help us make bread and alcohol, and more recently, to make antibiotics and clean up toxic spills. Now the Office of Naval Research is hoping the one-celled organisms will reduce the costs of producing a missile propellant, a...Traditional Christmas snack under threat
...sive harvesting practices continue in persistently exploited areas. Writing in this week's edition of the inte...commend close monitoring and careful management of exploited populations to avoid future regeneration failure and encourage establishment of younger trees. Other...A new hope for heavy metal contaminated soils
...nd tolerance at the molecular level. For this they exploited the fact that A. halleri is very closely related to the genetic model plant A. thaliana, of which the genome has been sequenced. In contrast to A. halleri, A. thaliana is metal sensitive and immobilises excess metal ions in the roots, thereby limitin...Biofilm antibiotic resistance may be susceptible to genetic approach
... have a genetic chink in their armor that could be exploited to combat the infections they cause. A study led by Dartmouth Medical School (DMS) researchers used a genetic-based approach to begin to understand how biofilms can withstand antibacterial treatments. The results of the study, published in the Novem...Transparent fish provide window on blood formation and marrow transplantation
...r light-scattering characteristics. The scientists exploited this property to study the characteristics of blood cells in mutant fish that were known to have defects in blood-cell formation. "This surprising property of zebrafish blood cells proved to be a tremendous advantage for us because now we can use thi...US crackdown on bioterror backfiring
...to work on projects involving agents that could be exploited as bioweapons, even though the US government is pr...p code that requires crucial details that could be exploited by bioterrorists to be removed from scientific papers. But the regulations the US government has br...Collapse of seals, sea lions & sea otters in North Pacific triggered by overfishing of great whales
.... "In principle we think that when any species is exploited to excess - be it pollock, halibut or whales - it may trigger a broad and devastating 'domino effect,' and the ecosystem impacts are significant." Estes had already shown that killer whale predation had a significant impact on sea otter populations...