Tag: "failing" at biology news

Inhibiting cardiac protein through gene therapy improves human heart cell function

... in calcium regulation can improve the function of failing heart cells, according to a study in the February ...ls calcium flow within cells and may be reduced in failing hearts. By blocking normal calcium regulation in heart cells, the natural inhibitory actions of ph...

Diabetes tied to altering of the heart's circadian clock

...n's circadian clock. This could lead to the heart failing to initiate important stimuli to several internal and external environmental changes, thereby contributing to heart failure. Some 143 million patients worldwide are diagnosed with diabetes, almost five times more than estimates of ten years ago. Hea...

As bodies age, disease-fighting cells lose punch

... less capable of fighting infection because their failing T cells no longer effectively orchestrate the cellular immune response. Although T cells do appear to play a role, Cambier and his colleagues believed there was more to the story. Their current paper started with a basic paradox. Older mice, and hum...

Potential therapy reported for children, adults with end-stage liver disease

...vanced liver disease develop hyperammonemia as the failing liver can no longer process ammonia, a natural by-product in humans. "Interrupt glutamine formation and the swelling that follows and we might be able to prevent brain damage and death," says Brusilow. Experimental evidence suggests that glutamine fo...

Genetic fingerprint of lung cancer predicts treatment outcome

...n lung cancer patients that had high likelihood of failing standard treatment compared to those with a better prognosis. Generally, about 50-60 per cent of lung cancer patients treated by surgery will have their cancer reoccur. "This genetic fingerprint is actually a pattern of genes in the lung tumor that c...

New drug boosts fight against HIV, researchers find

...d to the nelfinavir group, in which 33 per cent of failing patients developed resistance. "Two main barriers to treatment are resistance to the drug and adherence to a therapy schedule," notes Walmsley. "With effective therapy, we anticipate that about 60 to 70 per cent of patients will have their virus leve...

Smoking decreases men's chances of fatherhood by IVF and ICSI

... also in ICSI. The chances of the whole procedure failing and no pregnancy occurring was two to three times higher in smoking men compared with non-smokers. Smoking probably has an adverse effect during the fertilisation procedure, but, in addition, smoking damages the DNA in sperm and this may hamper the ...

ACE inhibitor drug used to delay heart failure as effective in blacks as whites

... cornerstone of therapy in patients with a weak or failing heart, irrespective of their race or ethnicity," Drazner said. Dr. Mark Strong, assistant professor of internal medicine at UT Southwestern, also participated in the study....

SMU and UNC researchers make an advance in our understanding of gene regulation

...ly, causing an overproliferation of blood cells or failing to make cells differentiate properly. About 15 Polycomb-group genes have been discovered so far. The E(z) gene was discovered by Swedish researchers in 1974. Rick Jones, an associate professor of biological sciences at SMU, has been using genetic an...

U-M researcher calls for new approach to biological disarmament

...ed States signed in 1972) reopened in Geneva after failing to reach agreement last year on an inspection regime designed to strengthen the treaty. Given strong resistance from the Bush Administration, the most that is expected is a series of annual meetings that keep multilateral discussions alive. "It's ir...

Study shows first direct evidence that transplanted muscle cells can take root in damaged hearts

...cle, could one day be used to help repair damaged, failing hearts without danger of rejection," says U-M card...iting a heart transplant to replace their scarred, failing hearts, and scheduled to receive an implanted heart-assisting device called an LVAD to help them sur...

UF study suggests schools boost empty calories to raise test scores

...s, particularly those threatened with at least one failing or sanctioned school, respond by giving students m...aminations. Schools with large numbers of students failing the test face sanctions that may include loss of state funds. In districts with at least one school...

Ocean report calls for the immediate creation of marine reserves throughout the United States

... losing important commercial species, and they are failing to replenish themselves at the same rate they are being damaged or exploited." Among the major threats to healthy ocean ecosystems are overfishing, habitat alteration, pollution, runoff from land, aquaculture, invasive species, coastal development an...

Dyslexic children`s brains operate more like those of normal readers following training

...the crisis we are facing in the number of children failing to meet [educational] standards,`` she said. The No Child Left Behind Act of 2001 places an emphasis on teaching methods that have been proven scientifically to work. Dyslexia, sometimes called ``word blindness,`` is a common disorder, affecting 5 to...

Are we mice or men? Gene mutation linked to improving heart failure in mice proves lethal in humans

...ifferent in humans when compared with mice? Are we failing to consider the critical differences between mouse and man? Two studies published in the March 14 issue of the Journal of Clinical Investigation led by Evangelia Kranias and researchers at the University of Cincinnati reveal that a mutation in the hu...

Nitric oxide-like drug could revive a failing heart

"This is a truly novel pathway for stabilizing a failing heart." David A. Kass, M.D. The 5 million or so h...tric oxide could better restore normal function to failing hearts. Studying normal dogs and those with heart failure, researchers gave the animals an infusion ...

An unexplored genomic terrain in a handful of dirt

...ng, with the resulting phage genomes succeeding or failing based on their competitive evolutionary advantage. "Most of the time you get genomic trash, garbage that is destined to go nowhere," Hatfull said. "But natural selection can choose the small number of recombinant genomes that are viable, that have th...

St. Jude researchers use DNA chips to determine how leukemia cells respond to different drugs

...searcher to identify some patients at high risk of failing treatment. Our previous studies of ALL focused on differences in gene expression in cancer cells before the patients were treated with chemotherapy, Evans said. In this latest study we identified for the first time the changes in gene expression cau...

UCLA study finds clues to diabetes puzzle

...tion of his handwriting, possibly secondary to his failing vision, are consistent with a diagnosis of type II diabetes," he said. "The disease certainly occurred in Germany during Bach's lifetime, being known as 'honigsusse Harnruhr' or honey-sweet urine disease."...

ART laws put patients at risk and should be changed, warns head of Germany's IVF registry

... of our patients. German regulations are obviously failing to do so."...

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