Tag: "failure" at biology news
Heart Inflammation Declining In The United States
...Hopkins between 1985 and 1996 with new-onset heart failure
or abnormal heartrhythms. Myocarditis was present in 157 patients (9 percent) who had no otherdisease associated with heart inflammation. The number and proportion of patients with primary myocarditis decreasedsignificantly during the time ...
Gene Identified For Heart Defect That Causes Sudden Death In Young People
...for asignificant number of sudden deaths and heart failure
in young people has beenlocated -- or mapped -- by...o notsuffer sudden death develop symptoms of heart failure
-- including swelling ofthe hands and feet and shortness of breath -- in their 30s and 40s, and usua...
AHA Issues Scientific Statement On Infective Endocarditis
...e and manage the major complications, such asheart failure
and infections." The Duke guidelines offer three categories of diagnosing endocarditis to helpphysicians manage patients who are affected. The categories include: 1)"definite" cases proven at surgery; 2) "possible" cases, which means there issome e...
American Heart Association Announces Top 10 Research Advances For 1998 -- Gene Therapy Among The List
...t the heart tissue of people with congestive heart failure
can recover some of its function. In both studies...action of the heart for patients with severe heart failure
who are awaiting heart transplantation surgery. In the first report, scientists described how some ...
Molecular Doorway Holds Key To Gene Therapy
...of cells may beimportant factors in the success or failure
of human gene therapy using alteredviruses, according to researchers at the University of North Carolina at ChapelHill. A report of their study published Jan. 4 in the journal Nature Medicineapplies directly to a promising gene therapy method...
Gene Therapy Trial Approved For Rare Anemia
...with Fanconi anemia, the bone marrow fails. It's a failure
state likeliver failure
or heart failure," says Dr. Christopher E. Walsh, assistantprofessor of medicine at UNC-CH School of...
Immunex And Wyeth-Ayerst Laboratories Advance Enbrel Into Phase II/III Clinical Trial For Chronic Heart Failure
...cal trial withENBREL (etanercept) in chronic heart failure
patients, one of the firstlarge-scale studies unde...trolled multi-dose Phase Isafety study in 47 heart failure
patients demonstrated that ENBREL was welltolerated. The incidence of adverse events was similar in ...
Common Respiratory Virus Identified As One Cause Of Heart Muscle Damage That Can Lead To Sudden Death
...hich leads to disabling and eventually fatal heart failure
and canalso cause sudden death. Physicians can treat the fever and inflammation commonly caused by adenoviruses,but not the virus itself, says Towbin. When symptoms occur, drugs can be usedto strengthen the heart's weakened pumping ability, but in s...
Scientists Discover Function For Type III TGF-Beta Receptor
...defects in valves or septathat can be explained by failure
of the AV cushion cells to transform andmigrate. Recently, these defects have been associated with damage to a region ofchromosome 1 that includes the gene for the Type III TGF-beta receptor. Severalgroups are working hard to identify mutations in t...
Genetic Research Boosts Understanding Of Iron's Path Through Body, Diseases Of Iron Metabolism
...is causesdiabetes, impotence, arrhythmia and liver failure
if untreated--and doctors oftenfail to diagnose it. Moreover, researchers are realizing that iron loading ismore common among African Americans than previously thought. Iron metabolism was intensely studied in the 1950s and '60s, when thephys...
Osiris Therapeutics Reports Key Findings in SCIENCE Verifying Existence of Adult Stem Cells
...ic injuries, transplant medicine, congestive heart failure
and degenerative diseases," Burns concluded....
Zinc Reduces Child Mortality By More Than 34%
...s the severity of the episode and risk oftreatment failure
or death. Zinc experts from Johns Hopkins include: Robert E. Black, M.D., M.P.H., Sunil Sazawal, M.B., B.S., Ph.D., M.P.H....
Genes Found That Label Cell Proteins For Disposal
...een implicated in cancer and otherhuman illnesses, failure
or disruption of this cellular mechanism may promotethe disease process, according to Dr. Yue Xiong, assistant professor ofbiochemistry and biophysics at the UNC-CH School of Medicine. "Balance is the key word. How the cell cycle of growth an...
Sharks Get Porthole Of Opportunity
...th. But Pikitch was quick to note NMFS' failure
to enact tougherrestrictions for swordfish, which have been dwindling in both size and numberfor more than two decades. According to Pikitch, NMFS failed to take meaningfulsteps to rebuild the depleted swordfish stock. "The U.S. has a real o...
Studies Of A Gene For A Rare Form Of Rickets Shed Light On Vitamin D Deficiencies
...ample bone growthproblems caused by chronic kidney failure
or by aging. Anthony Portale, M.D., professor of p...ard Children's Hospital at UCSF.People with kidney failure
do not have a genetic deficiency in vitamin Dmetabolism, but without normal kidney function they los...
Cedars-Sinai Medical Center Physicians And Scientists Present Findings At Annual Meeting Of The Pediatric Academic Societies
...s, including abnormally small eyes,lack of a nose, failure
of the testicles to descend into the scrotum, anddefective function of the gonads. The presentation describes the gestational stages during which thesemalformations should develop and suggests certain genes that may be responsiblefor the disorder. Th...
Scientists Use Fossilized Emu Eggshells To Discern Changes In Vegetation, Provide Additional Evidence Of Human Impact On Australian Landscape
..."Johnson says. The researchers speculate that the failure
of monsoonprecipitation to reach the interior may be due to systematic burning by humans,which led to large-scale modification of the vegetation across the semi-aridzone with trees and shrubs being replaced by desert scrub. Such a change would have d...
Reproductive Signals Affect Lifespan In Roundworm C. Elegans, Offering Possible Insight Into Human Aging Process
...than normal. And the explanation is notdue to the failure
of the animals to produce progeny - which researchers havespeculated causes wear on the body, and thus aging - because animals that failto have progeny for other reasons age normally. Instead, the lifespan of the animal appears to be sensitive to t...
'Cousin' Of Snake Venom Toxin Found In Mice
...o are killed by venomous snakes die of respiratory failure
because thealpha-neurotoxins shut down the diaphragm muscles, causing suffocation. While searching for genes that regulate brain development, Heintz andpostdoctoral associate Julie Miwa found lynx1. The investigators decided tocontinue studying lynx...
Treatment restores normal heart rhythm in patients
... lead todecreased cardiac output, congestive heart failure
and low blood pressure. "Since atrial fibrillation is the most common arrhythmia (irregular heartrhythm) observed in patients who visit a primary care setting, it is importantto improve our understanding of the options available for treatment," says ...
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