Tag: "family" at biology news
Yale scientists visualize details of how hepatitis C unwinds RNA
...on inside cells. NS3 is one member of an extensive family
of helicases and is used as a model for studying unwinding activities of motor proteins. Their findings are particularly important because NS3 is a major drug target against HCV and understanding the helicase function will aid in the development of ...
Antimalarial substances found in New Caledonian sponges
...larial activity in 25 members of the phloeodictine family
of alkaloids, isolated from one of the species of ...onge Oceanapia fistulosa. The phloeodictines are a family
of alkaloids, composed of three large groups distinguished according to differences in their chemica...
Research reveals role of gene in infertility
...rating diversity among individuals within the same family
and throughout the entire the population. These very similar molecules of DNA, along which specific genes lie at the same point on each strand, are brought together by the molecular machinery of the cell to form a two-chromosome structure known as ...
HIV reveals evolution of a primate defense against intragenomic infiltrators
...nd is surprising. The gene, APOBEC3G, belongs to a family
of primate genes that produce enzymes (in this case, APOBEC3G) that "edit" DNA and RNA, by slipping into viral particles and inducing mutations that replace one base (cytosine) with another (uracil) as the virus undergoes reverse transcription in the...
Researchers identify gene for a primary form of sudden infant death sydrome (SIDS)
..., along with their parents, siblings, and extended family
members. Using Affymetrix SNP arrays -which examine 11,555 single letter, or nucleotide, variations in the genome known as single nucleotide polymorphisms-the researchers narrowed the location of the disorder to a region on chromosome 6. By correlati...
Songbirds escaped from Australasia, conquered rest of world
...ning the DNA sequences of two genes in all but one family
(a closely related group, such as "crows and jays" or "warblers") of passerine birds, Barker and his colleagues made a startling discovery. "It was thought that the Passerida arose in Eurasia about 40 million years ago," said Barker. "But we found...
Living at home helps young mothers stay in school
...ther's parents might help her finish school if the family
shares a home. Yet critics of the policy worry ab...with their parents before the baby was born, or if family
relationships were abusive. To explore this issue, we used the Infant Health and Development Program...
JCI Table of Contents, 15 July 2004
...g cells called osteoblasts, proof that this entire family
of drugs is involved in bone loss has yet to be es...s. The work here indicates that ritonavir may a PI family
member that is bone sparing and therefore able to prevent bone-loss in patients undergoing HAART, an...
New drug shows promise against Gleevec resistance in mice
...at Abl looks structurally quite similar to the Src family
of oncogenes that also produce kinases. Yet, as Kuriyan's work demonstrated, STI-571 does not inhibit the Src proteins because they maintain a different shape when in their inactivated, or "off," position. As Kuriyan prophetically stated at the time,...
New pulmonary hypertension guideline challenges use of common medication
...l also advises genetic testing for patients with a family
history of PAH and advance screening for patients with certain chronic diseases who are predisposed to PAH. "Calcium channel blockers are regularly used to treat high blood pressure because they limit calcium entry into the cells and dilate the con...
Asian bird flu became highly pathogenic through continued circulation and gene swapping
... protein called M2, known to cause resistance to a family
of antiviral drugs used to treat human influenza. ...resulting virus would be resistant to an important family
of drugs. In fact, the common human influenza H3N2 has been found inside pigs in southern China, a...
UCSD undergraduates participate in collaborative studies abroad on cyberinfrastructure
...mizations. Nguyen, who is the first member of his family
to attend college, aspires to incorporate a Rocks cluster, NIMROD, and GAMESS into a ready system for scientific data computing. And Kondrick will work on modifying the NIMROD infrastructure to work with two computational chemistry codes, GAMESS and ...
New compound 'highly efficacious' at reducing human tumour growth
... to the molecular pathology of cancer. CDK's are a family
of enzymes required for the correct timing and order of events in the cell division cycle. Vascular endothelial growth factor (VEGF) / VEGF-receptor tyrosine kinase (VEGF-RTK) and platelet-derived growth factor (PDGF)-RTKs are two molecules known to ...
JCI table of contents, 1 July 2004
...roken down in the liver or in fat tissue. One gene family
thought to be involved in this increasing free fat...and as well as other mechanisms to block PPAR gene family
action. In doing so, they were able to dissect specific roles for different members of the PPAR gene...
The key to cell motility
...se Rac is one of the most important members of a family
of proteins known as the Rho GTPases. This family
of proteins binds to a small metabolic product called GTP, which acts as a critical regulator of Rho...
New milestones on the path to conquering HIV drug resistance (AIDS)
...he drug, tenofovir, or the DAPY (diarylpyrimidine) family
of compounds, and offers explanations of the mecha...o explored another mechanism displayed by the DAPY family
of compounds. Arnold and coworkers have worked extensively with the DAPY compounds, the subject of t...
Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice
...sue from the experimental mice. Wnt10b is one of a family
of 19 related proteins. Wnts (pronounced "wints") regulate the complex changes that take place as an embryo grows. Part of this process is the development of fatty adipose tissue, which contains fat cells called adipocytes. Ormond A. MacDougald, Ph.D...
Rare, tiny find in West Australian waters
...ng what looks like 6 legs is a phaeodaria from the family
coelodendridae, also known as a radiolarian. Measuring only 1.4 mm, the organism was found during an investigation of ocean eddies by the National Marine Facility, Southern Surveyor. "It was a case of being in the right place at the right time with t...
'Mighty mouse' gene works the same way in people
...ead to problems as the boy gets older. While other family
members -- the boy's mother and her brother, father and grandfather -- were also reported to have been usually strong, only the mother's DNA was available for analysis along with her son's. Schuelke discovered that only one copy of the mother's myost...
Clinical judgement still counts strongly alongside genetic testing
...chniques and technologies, such as photographs and family
trees, have developed with which to do genetic pro...e grave ramifications for other, including future, family
1 2 3 4 5 6 7 8 9 10