Johns Hopkins gene hunters pinpoint new cancer gene target
...tions have been found, called PIK3CA, is part of a family of genes encoding lipid kinases, enzymes that modi...e been studying the biochemical properties of this family of genes for more than a decade, until now, no study revealed that they were mutated in cancer. Kin...Gene variants may increase susceptibility to type 2 diabetes
...inactive people and is more common in those with a family history of diabetes. In the United States, type 2 diabetes disproportionately affects African Americans, Hispanic/Latino Americans, and American Indians. Affecting about 17 million people nationwide, this form of diabetes accounts for 90 to 95 perc...Stress hormones and heart failure
...ences, the study establishes a firm link between a family of stress hormones called urocortins and heart dis...gues found that a specific member of the urocortin family of proteins, called urocortin II, administered intravenously in a small dose, significantly enhanced...Biochemistry and Molecular Biology: Research at the Interface of Biochemistry and Human Health
...for his groundbreaking research on the most common family of receptors, including the beta-adrenergic receptors that mediate the body's fight or flight response as well as virtually all sensory receptors. Since the beta adrenergic receptors respond to the hormone adrenaline, continuing research on these re...Top US scientist honored with prestigious award
... contribution in the area of T cell research - the family of cells that help the body fight off disease - and their effect on the immune system. Dr. Marrack has spent much of the last 35 years studying the features of T cells and how they can trigger autoimmune diseases, such as rheumatoid arthritis. Her w...... a fantastic resource for genealogists researching family names and places. For more information, call Butch Kinerney (yep, it's Irish) at 703-648-4732 or email at bkinerney@usgs.gov ....UVa researchers describe method of protecting chromosomes during cell division
... It is already clearly established that the Aurora family of kinases is overexpressed in many cancerous solid tumors."...JCI table of contents, March 1 2004
...dundant properties in liver injury The NF-kappa B family of proteins orchestrates cellular responses to injury by regulating immune function, inflammation, cell growth, and cell death. Induction of NF-kappa B is tightly controlled by two I kappa B proteins, I kappa B alpha and I kappa B beta, which prevent...Researchers discover new family of Atlantic corals in groundbreaking study
...cal Research Institute in Panama, has identified a family of corals found only in the Atlantic--a first for such classifications in that ocean--in a study that could transform the way corals are viewed and classified throughout the world. Researchers from the United States, Brazil, Taiwan and Japan revealed...Double mastectomies significantly lower risk of breast cancer in women who are genetically at risk
...ther mutation if a woman has a particularly strong family history of breast cancer. If a woman is found to carry either mutation, she has a greatly increased chance of getting breast cancer before age 70....Revised guidelines published for testing for hereditary type of colorectal cancer
... inherited and therefore may mean that a patient's family members are at an increased risk of the disease. T...ults from inherited mutations, it is possible that family members of patients with HNPCC also have the genetic characteristics that put them at an increased r...Structure solved by Scripps scientists shows one way that body controls gene expression
...l's machinery. TIS11d belongs to a common family of regulatory proteins of this latter type. It regulates the levels of many important proteins involved in the body's inflammatory response, such as tumor necrosis factor (TNF) and interferons, by marking the TNF and interferon mRNAs for destruction....Unlocking the genetics and evolution of the dog could prove beneficial for humans
... will present data on another member of the canine family the fox. He will show that some of the same genet...tor that eventually gave rise to the modern canine family in which the fox is one extreme and the dog is another. By working closely with their owners, Lark ...New study suggests brains of autistic children can be trained to recognize faces
...ism. With 300 families signed up, the UW multiplex family study, which Schellenberg will describe at the AAAS meeting, is one the largest worldwide efforts aimed at identifying the location of autism genes. The researchers believe that there are at least five genes that come together to make a person vulner...Immune system's attack dogs kept on genetic leash
...cription factor, NF-B. "This protein belongs to a family of transcription factors heavily implicated in var...mmune cells." Peng speculates that other Fox gene family members may play an intrinsic role in keeping immune cells quiet or in preparing them to battle inva...Penguin bones from 'land of fire' rewrite bird's evolution
... a larger, more comprehensive study of the penguin family tree is necessary before the full story of early penguins in the Land of Fire can be told. But she's confident that the discovery will help clarify the timing and pattern of penguin diversification. "This is the first vertebrate from that distant epo...Out-of-balance ecosystems play role in demise of amphibian populations
...merging findings also raise a question about which family of parasites may be of greater importance in terms of amphibian survival. The parasite that attacks the kidneys is far more widespread than the one causing deformities. A central question is why are more of these parasites being found in frogs. They ...Dinosaur fossil record compiled, analyzed
... genera, or classes, as well as various clades, or family tree branches, of dinosaur classes. Heathcote fo...le dinosaur studies and compared them with smaller family trees within the context of the whole dinosaur data, commonly known as the Dinosauria. She also ana...New hereditary cancer mutation found -- arrived with a German immigrant almost three centuries ago
...CC, which is usually diagnosed based on a person's family history or the presence of certain gene mutations ...ive genes, or both. However, most people with a family history of the disease do not have an easily detectable mutation, and the genetic tests for mutation......the study results apply to people without multiple family members with Alzheimer's disease, Mayeux said. He also noted that the study participants differ from the general U.S. population, especially in years of education. "Because public education was limited in the Dominican Republic from 1930 to 1961, peo...