UNC scientists block cellular enzyme activity involved in cancer progression
...e to specifically inhibit FAK activity. "If we can figure out the minute details as to how FAK works, then we can determine how to block its activity," Schaller said. "And if we do that, then we might be able to apply what we learn therapeutically against cancer." To better understand FAK activity, Schaller...Temple virologist receives NIH grant to continue investigation of HIV dementia complex
... get this type of dementia," says Rappaport. "This figure has dropped from 20 to 30 percent because of the s...f highly aggressive anti-retroviral therapy. This figure might increase if drug therapy begins to fail in patients who are on therapeutic regimens for longer...Researchers discover protein that dissolves amyloid fibers
...ed the same effect. That certainly made us want to figure out what was going on," says Lindquist, who is also a professor of biology at MIT. "It was hard to come up with a definitive experiment in a living cell that would explain this sort of thing." In this new study, Lindquist and postdoctoral researcher ...Stem cells toward sperm cells and back again
...zed cells can reverse course might help scientists figure out how to use stem cells to regenerate lost or injured tissue, or how to trigger remaining tissue to better heal itself. There is no immediate application for people, however, because little is known about the corresponding process in humans. "In fr...Scientists track protein linked to movement disorder
...what's known about other proteins like torsinA, we figure this means torsinA is probably taking something apart in the nuclear envelope," Hanson says. "The questions are: What is it taking apart and how is that important for the normal structure and function of the nuclear envelope? And how is that activit...Mimicking humpback whale flippers may improve airplane wing design
...ark head may act like a wing. The trick now is to figure out how to incorporate the advantage of the tubercle flipper into manmade designs, said Fish. The research team now plans to perform a systematic engineering investigation of the role of scalloped leading edges on lift increase, drag reduction and st...Busy sequencing technique saves money and time
...d software that allows us to sort out the mess and figure out the different sequences." Writing in the April issue of Genome Research, Brent and collaborators at Baylor College of Medicine, led by Richard A. Gibbs, Ph.D., director of Baylor's Human Genome Sequencing Center, discuss related techniques in ge...Fire ant killing protozoa found in 120 Texas counties
...ectively ants can make a huge impact. Worldwide, a figure for ants comprising 15 percent of all terrestrial animal biomass is not out of line. "No one really knows for sure what percentage ants constitute of the animal biomass. But one thing is for certain. If you really want to disrupt the ecosystem, dis...World's oldest modern hummingbirds described in Science
...oday's hummingbirds. "The tip of the wing makes a figure 8," Mayr explained. This wing motion allows hummingbirds to hover in front of the flower and eliminates the need for a perch. "The remainder of the skeleton is also very hummingbird-like," Mayr said. Mayr noted, however, that today's hummingbirds hav...Sediments in many Central Valley streams contain toxic levels of pyrethroid pesticides
...que is that we looked at the toxicity and tried to figure out what was actually causing it. We detected organochlorines, such as DDT and chlordane, in the sediments, but at concentrations not high enough to cause the toxicity we noted, whereas concentrations of pyrethroids were high enough to account for th...Human brain works heavy statistics learning language
...n paper and a calculator, you'd be hard-pressed to figure out the statistics involved," says Newport. "Yet after listening for a while, certain syllables just pop out at you and you start imagining pauses between the 'words.' It's a reflection of the fact that somewhere in your brain you're actually absorbi...AIUM to honor ultrasound pioneers at its 2004 Annual Convention
...ltrasound. Joseph H. Holmes, MD, was an important figure to both the field of diagnostic ultrasound and the AIUM. The 2004 Distinguished Sonographer Award will be presented to Paula Woletz, RDMS, RDCS, MPH. Established in 1997, the Distinguished Sonographer Award is a means of honoring an AIUM member so...DFG establishes first German-Sino Research Training Group
...ning Groups are international doctoral students, a figure almost three times as high as the national average. For further information on the DFG's Research Training Groups, please visit: http://www.dfg.de/en/research_funding/coordinated_programmes/research_training_groups For more detailed information, pl...Chlamydia in men now also linked to infertility new findings
... study group 3.7% exhibited Chlamydia DNA, but the figure was over 13% in the infertile antibody positive couples. Associate Professor Jan Olofsson, head of the research team, said: "As anticipated, we found a raised prevalence of Chlamydia trachomatis IgG antibodies in the infertile population compared wi...Researchers find evidence that sea turtles navigate with magnetic maps
... map," Ken Lohmann said. "In other words, they can figure out where they are relative to home using magnetic field information. This is a far more complex use of the field than just having a magnetic compass that gives direction." Last year, the UNC couple and one of their graduate students showed that spin...Ocean dye to help Rutgers scientists trace Hudson River's path miles into the Atlantic
...copic ocean plants. The rotation of the earth will figure in the model because it causes ocean water in the northern hemisphere to turn to the right. This phenomenon, called the Coriolis effect, drives the plume up against the New Jersey coast. In previous testing, water from the Hudson River Plume wa...Newly discovered gene controls levels of 'bad' cholesterol in mice
...rol in humans but this work in mice should help to figure this out. "If the same mechanism Maxwell found in mice pertains to humans and we could inhibit Pcsk9 with drugs, this should increase the number of LDL receptors on cells and in this way lower LDL levels in the blood. This might offer another thera...Genome-wide screen reveals new tricks of old genes
...ng. Reading all there is to know about 50 genes to figure out what new knowledge may be lurking in the hayst...ping information from two screens, we were able to figure out what Mother Nature was trying to tell us that wasn't too complicated for us to understand." Whi...The Hunter's Breath tells a story of adventure and discovery in Antarctica
...ation run free as you explore the world and try to figure things out." Williams said her inspiration for reaching beyond the usual academic audience for her work--first with the expedition web site and ultimately with this book--came from Stephanie Mills, founder of the Ida Benson Lynn Chair in Ocean H...Is a single bout of exercise helpful or harmful in getting a good night's sleep?
...population belonging to health clubs in 2000. This figure is expected to reach 41.1 million members, or 14 percent of the population, in 2006. Previous research has demonstrated that, in general, quality of sleep improves after regular physical exercise. However, a number of factors such as the particul...