Evolution Re-Sculpted Animal Limbs By Genetic Switches Once Thought Too Drastic For Survival
...ion. "This variation is what everyone had hoped to find for this class of genes," hesaid. "They hoped you would find a change in morphology that mirrored what washappening with respect to expression of the gene. They ...New Gene May Intensify Breast Cancer Growth
...irst clinical studies using thegene as a marker to find out how it affects the course of breast cancer. "Do thepatients who make a lot of the message from this gene respond differently totherapy, do they have a different clinical outcome, are their tumors different,do they develop at a different age or at...Newly Discovered Human Protein Provides Important Target For Cancer Therapy
...l companies have screenedthousands of compounds to find agents capable of blocking telomerase. Now thatwe...ctor in normal humanaging.) "Cancer cells find a way of switching telomerase activity on, whichgives them a tremendous competitive advantage," Dr. ...Female Fireflies Lure Males For Defense Chemical
...ommented. "The more we study insects, the more we find them taking chemical defenses from plants and from other insects. And plants are 'experts' at gleaning useful chemicals from microorganisms. "We humans are slow learners, but we're starting to catch on," Eisner added. "There's a world of natural pr...Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
.... They expected that. But they didn't expect to find that the combination of missing genes was lethal to the female mouse embryos. By day 9.5 of gestation the female mice stopped developing and died. "The embryo was undergoing global apoptosis, or programmed cell death," he said. "The...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
...lish this task, in part, by searching databases to find conserved biological motifs, first elucidated using simple model organisms like bacteria, yeast, worms and flies. By decoding the human genome, scientists can begin to decipher the genetic aspects of all disease, leading to improved treatments and ev...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
...ymptoms. We now have an important clue to help us find that trigger and, we hope, to stop it." The members of this research team have been searching for the DYT1 gene since the early 1980s, when many of them worked together at Yale University. In 1989, they discovered the first marker for the gene, whi...Molecular Piracy Turns Protein Into Traitor
...mical process used by Glaxo Wellcome scientists to find new drugs. After lifting a human gene for a chemokine receptor agonist, the virus used genetics to perform a type of biological 'combinatorial chemistry'. This process can be used to produce a family of similar molecules. The virus then tested the re...Study Sheds Light On Behavior Of Middle-Age 'Undertaker' Bees
...tored how swiftly undertakers worked. "We didn't find any evidence for learning for this particular task,"Trumbo said. "This rules out one of the major hypotheses that hasbeen put forward for middle-aged specialization: That social insects willget better and better at what they do." Previous research...Planned Burning In Forests A Boon To Several Species Of Birds In Illinois
...ity and nesting success. "We haven't been able to find a lot of ways to increase the reproductivesuccess of birds living on the state's fragmented landscape," he said. "It's been a real problem. Illinois has been a population sink foryears. What we may be able to do for some species with these burnings...Trojan Horse Virus Controls Hiv Infection
...allow direct, invivo delivery of a vector that can find its destined target in the body. Thereshould be no need for ex-vivo manipulation of cells." She envisions manypotential applications of this research. Surface-modified live vectors like VSV could be used to shuttle into the bodyviruses or toxins to......ce seedwithout pollination. The hunt is now on to find equivalent genes in commercial plants likerice - the world's biggest crop, and the staple diet for billions of peopleglobally. "In most crop plants, the male parts of the flower transfer pollento the female parts, prompting the grain to develop," Dr...Wonder Thread: UD Scientists Report First Protein With Collagen And Elastin-Like Domains
...kin," Slavkin says. Curious Forms of Collagen To find out what makes byssal threads so special, Qin and ...ethal to the animal. So, it's quite fascinating to find a missing glycine in a perfectly functional collagen subjected to great stress and strain in marine ...Gene For Last Major Form Of Batten Disease Discovered
...chers mustovercome many technological problems and find a way to circumvent theblood-brain barrier for gene therapy or enzyme therapy to be successful forBatten disease. Discovery of this and other proteins involved in Batten disease may ultimatelyyield new insights about how humans age. Previous studie...Smoking Mice Lead To Emphysema Breakthrough
...astase -- that could be up to the task. To find out if macrophage elastase causes emphysema, Shapiro and otherscreated a strain of mice that lacked the enzyme. He calls them "mighty mice" andestimates their value at tens of thousands of dollars apiece. "We couldspeculate for years about the functi...Plant-Based Therapies Examined For Colon Cancer Prevention
...participants. "Ideally, we would like to find the lowest, optimal dose of each of thethree plant compounds that would safely inhibit the development of colorectalcancer," explains Shiff. The study lasts for up to 10 weeks. During the first two weeks,participants eat a controlled diet ...Pharmaceuticals Manufactured In Insect Larvae
...Yonkers, N.Y. The purpose of the institute was to find ways to meet the food and health needs of an increasing world population. BTI moved to the Cornell campus in 1978....Environmental Engineers Demonstrate Effective Method For Trapping Highway Pollutants
...of highway during the fieldtest, so Sansalone must find a consistent and simple method forproducing huge quantities of coated sand. "When we made the prototype, we made more coated sand than hasever been artifically produced on Earth. It was a realundertaking," said Sansalone. He will also work on modifyi...... treat but cannot cure diabetes, we believe we can find treatments to allow these Gulf War veterans to live more comfortable and productive lives."...