Tag: "folding" at biology news

UCSB physicist devises way to observe protein folding

...lved in the fight against diseases by studying the folding of proteins, which they hope will eventually lead ...se and even some cancers are the result of protein folding that has gone awry. Since proteins in the body perform different functions according to their shape,...

NSF news tips - September 22, 2003

...tions such as unfolding a telescope lens in space, folding proteins and stowing air bags. NSF supported Demaine's postdoctoral fellowship (DMS-0102015), and he is now a co-PI on an NSF Information Technology Research award to design a network architecture that integrates millions of sensors (ACI-0205445). ...

Livermore & NIH scientists create technique to examine behavior of proteins at single molecule level

...rstand a fundamental biological process of protein folding that is important for many diseases. The work, pr... were able to access information about the protein folding reaction that was never available from ensemble measurements or even from the newer single molecule ...

Tipping the balance of prion infectivity

...m the prion went into, if we could slow down which folding route the prion took, we could change the specific...on small-molecule compounds that influence protein folding to favor non-toxic over toxic misfolded forms."...

Popular Science announces second annual 'Brilliant 10:' the country's top young scientists

...thorny problem: which shapes can be made simply by folding a piece of paper, as many times as you like, then snipping off a corner and unfolding it. He found the answer and helped launch computational origami, a hybrid discipline--part computer science, part mathematics--that explores complex geometry concep...

Bio-X symposium will be held at the Clark Center on July 31

...erests - from image-guided radiosurgery to protein folding to the effects of carbon dioxide on coral reefs. A major component of the Bio-X program is the encouragement of cross-campus collaboration in the biosciences. In that spirit, the researchers at the symposium represent seven departments from three sch...

In potentially important discovery, scientists find two forms of genetic material chromatin

...length. This compaction is achieved by coiling and folding the DNA around proteins." Together, he said, DNA and proteins are called chromatin, and it is chromatin that one sees in the familiar microscopic images of chromosomes. The basic unit of chromatin is called the nucleosome, which is like a barrel, and...

Pattern recognition method zeroes in on genes that regulate cell's genetic machinery

... converting sugar to energy, responding to stress, folding proteins, and building cellular components such as the nucleus. Kollers pattern recognition technique builds on statistical models and the widely used technology of relational databases to look for patterns across many different data sources, such as...

Computational method identifies genes that regulate cell's machinery

... converting sugar to energy, responding to stress, folding proteins, and building cellular components such as the nucleus. The Friedman and Koller team show that the method can not only recognize known regulatory modules, or clusters, but also predict previously unknown clusters and the genes that regulate t...

'Frontiers In Bioinformatics' symposium to be held by UB Center of Excellence in Bioinformatics

...rithms for the prediction of protein structure and folding pathways from protein sequence. His research group at UB's Center of Excellence developed PROSPECTOR, an algorithm for protein-interaction prediction that works on proteins for which little structural information exists. For more information abou...

Alzheimer's protein jams mitochondria of affected cells; resulting 'energy crisis' kills neurons

... this domain, either by neutralizing its charge or folding it more tightly."...

First sightings of individual proteins as they fold

...ieved, could be obtained only through watching the folding process of individual proteins. Yet this presented... taking into account decisions made during earlier folding stages, their environment, and their own condition. The results verify what theoretical scientists h...

Mathematical models reveal 'molten' and 'glassy' states of RNA

...study of the related "protein folding problem." Researchers are working to understand the issues nature has to overcome to design new RNA sequences, because someday researchers may be able to design sequences themselves, for ...

First draft of 'periodic table' of protein structures helps visualize nature's universe of proteins

...m's next goal is to add to the map the less common folding motifs or building blocks. In fact, his group has already added many more folds and has found that they occupy the same "envelope" of the four elongated clusters in fold space, suggesting that this "map" constructed of the 498 most common folds is a ...

American Physical Society March Meeting 2003

...esearchers will present intriguing findings on the folding properties of RNA. Ranjan Mukhopadhyay ( ranjan@re...ve chosen a 4-letter genetic code because of RNA's folding properties. Ralf Bundschuh of Ohio State ( bundschuh@mps.ohio-state.edu ) and Terence Hwa of UC-San ...

January GSA BULLETIN media highlights

...he composition of the 140 to 20 Ma sandstones, and folding of all the basin strata into a regional north-vergent fold. The northern range-bounding thrust fault of the Tula uplift has been recently active, suggesting that uplift and thickening continues in the northern Tibetan Plateau. Early to middle Tertia...

January GEOLOGY and GSA TODAY media highlights

... African plates. High-resolution seismic data show folding and reverse faulting of the Quaternary units associated with submarine-landslide deposits, suggesting present-day tectonic activity. The location and dimension of these newly identified structures agree with the modeled source suggested for the 1755 ...

Nanoparticles could aid biohazard detection, computer industry

...e area into the limited space inside your skull by folding in on itself many times," Porter said. "But the advantage we found for computer chips is not that we can increase their 'thinking power,' per se. Rather, the resulting rough surface gives us a lot of nooks and crannies in which to secure a second gro...

'Knot' to be undone, researchers discover unusual protein structure

...ector of the Protein Structure Initiative. Protein folding theory previously held that forming a knot was beyond the ability of a protein. Joachimiak suggests that the newly discovered knot may stabilize the amino acid subunits of the protein. Such discoveries are just what the PSI aims for. "The PSI approac...

Folding@home scientists report first distributed computing success

...puters successfully simulated part of the complex folding process that a typical protein molecule undergoes ...hape to function normally. "The process of protein folding remains a mystery," said Pande, assistant professor of chemistry and of structural biology at Stanfo...

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