Brain Protein "Rescues" Neurons From Atrophy
...n cell growth, and that they might offer treatment for diseases involving gain or loss of brain cell conn...me similar molecule, must be the endogenous factor for which neurons are competing, and that the effects of deprivation are likely to be mediated by such a...Bacterial Toxin Surprises Scientists
... large protein movement as a transport device for the delivery of drugs into human cells, Dr...which parts of the protein are responsible for triggering channel opening and closing. As with much scientific discovery, the study's fin...Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...ad been carrying.One "ineffective" NO is exchanged for another "protected"NO. Blood pressure remains constant and blood flow maintained in order topromote oxygen transport. Hemoglobin detects how much NO has been removedfrom the bloodstream and compensates with SNO, the researchers believe.Still, the hem...Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
...s, the scientistssaid. The findings were prepared for presentation Wednesday at the annual meetingof the Federation of American Societies for Experimental Biology and willbe published in the May issue of the Journal of Toxicology and Environm......ukeUniversity Medical Center have deleted the gene for a crucial molecularcomponent of a mouse's nervous ...sdisease and may provide the first realistic model for testing new treatmentsfor psychiatric disorders. "We were astonished that a single genetic deletion...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...our model are intertwined, it is essential for them to untwist if they are to separate......division makes these enzymes prime targets for anticancer drugs. But until recently, scientists couldn't intentionally design such drugs be...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...olecular sabotage" could become a useful treatment for a variety of cancers. The research by Pendergast a...teractions may provide a useful therapeutic target for treatment of [chronic myelogenous leukemia] as well as other tyrosine kinase-associated human cancer...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...River Syndrome. They believe the effect also works for at leastthree other rare neurological disorders --...e. This is an observationthat provides a mechanism for a group of diseases." If drugs could block the protein interaction the researchers described,then ...Researchers Pinpoint Site For Petit Mal Seizures In Brain
...epsy. The findings may lead to more specific drugs for the disorder with fewer side effects, said Dr. Dav... 100,000 children in the United States and account for one-fifth of all childhood epilepsies. About 20 percent of children with petit mal seizures aren't h...Tumor Suppressor Gene Located In Liver Cancer Cells
... help researchers develop an early diagnostic test for liver cancer as well as new treatments, the resear...d Terry C. Orton of Zeneca are co-authors. Funding for the project came from the National Institutes of Health, Zeneca, the Proctor and Gamble Co. and MIT...New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
...-handed helical structure may offera unique target for a new generation of antibiotics designed to home i...emists attempting to design and construct proteins for use as medicinesand chemical probes. The researchers' next step will be to pinpoint the LpxA...Second Breast Cancer Gene Located
...ve Cancer Center and the UnitedKingdom's Institute for Cancer Research reported Wednesday. The gene, named BRCA2, likely accounts for the majority of inherited breastcancers not caused by BRCA1, the breast cancer susceptibility gene i...Duke Geologists Explore Alternative Way To Measure Ice Age Sea Bottom Temperatures
...gen 18 in foraminifera "have been the primary tool for reconstructing past temperatures in the deep ocean...h.D. candidate who performed the chemical analyses for the study, Dwyer said that more oxygen 16 is indeed present in warmer seawater, whereas oxygen 18 is......ed to fellowship in the American Geophysical Union for his pioneering work in the field of geochronology ...alactites, stalagmites and flowstones. Fortunately for geochronologists, such limestone-forming groundwater often also contains minute quantities of dissol...Computer Program For Quicker, More Detailed Mapping
... Genome Center. "Previously, it would take months for us to build a map," saidMyers. "Now we can rebuild...had to test everypossible combination of locations for each set of these DNA signposts tofigure out which one was correct. This method takes a large comput...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...te, doctors have not identified any specific genes for autoimmunediseases such as rheumatoid arthritis, although many researchers believethere may be several genes that, when defective, predispose people to developautoimmune disorders. The Duke researchers made the discovery while trying to understand...Rosemary May Have Anti-Cancer Properties
...he rats a diet supplemented with 1 percentrosemary for two weeks, using the same powdered rosemary readil...osemary study was funded by the American Institute for Cancer Researchand by Wakunaga of America, a food and pharmaceutical company. Harunobu Amagase, a ...Heat-loving Microbe Repairs Its DNA With Light
...at the 96th GeneralMeeting of the American Society for Microbiology. He has beeninvestigating the basic cellular properties of S. acidocaldarius for the past six years. In nature, S. acidocaldarius thrives in acidic, sulfurous hotsprings; in the ...Children Become Gorillas In VR Zoo
...l of a real outdoor areathat has ever been created for a virtual environment," Hodges said."Brian Wills (...ny zoo conservationist -- and build betterexhibits for spectators. But making an accurate virtual reality environment was only half thework. The virtual g...From Corn Rootworms To Art, Cornell's Reactor Is At The Core
... rootworms in soil, caught in the act of searching for the plant root. "Here you can see where they were ... absorbs them. The metal screen emits an electron for every neutron it absorbs, and that activates the emulsion and produces the photographic image on fil...