Molecular motor implicated in tissue remodeling
...o be a molecule-sized motor that extracts its fuel from the road it runs on, according to researchers at W...e remodeling, which can have a variety of purposes from organ development to tissue repair to metastatic invasion of tumors," says senior author Gregory Gol...Belgian researchers explore revolutionary approach to angiogenesis
...at killing tumours. Dr. Olivier Feron and his team from the University of Louvain Medical School in Brussels have turned the whole concept of targeting tumour blood vessels on its head. Instead of the conventional approach of trying to starve tumour cells of the blood supply they need to grow, they are do...Rare childhood genetic syndrome identified
...othy syndrome, the researchers show that it arises from a single, spontaneous, very subtle gene mutation in the mother's egg or father's sperm substitution of a single base pair. The reason so many body systems are affected is that mutation impairs a very fundamental molecule a type of calcium channel ...'Dead zone' area shrinking, Texas A&M prof says
...region in the northern Gulf of Mexico that suffers from low oxygen and results in huge marine losses - and...ear. "We found that the hypoxia had moved offshore from shallow waters to much deeper waters in the Gulf," DiMarco explains. "In other words, much of the de...Chemical derived from vitamin-E shows early promise as cancer drug
... of Experimental Biology and Medicine. They result from studies involving treatment of genetically identic...a-TEA, which Kline chose for further study in 1997 from 50 candidates. Because cancer may result from just one normal cell going awry, Kline and form...Scientists sequence genome of kind of organism central to biosphere's carbon cycle
...that may help to reduce its dependence on nitrogen from the surrounding waters. The genome work also shed...ists on the project, which includes 46 researchers from 26 institutions, also considered the evolutionary implications revealed by the genomic work. The res...Researchers find color sensitive atomic switch in bacteria
...id advance publication page of Science, scientists from The University of Texas Medical School at Houston and the University of California, Irvine, describe the versatile light-sensing protein at levels of resolution smaller than a nanometer--one billionth of a meter. "High-resolution X-ray crystallogra...Schepens Eye Research Institute receives 'Roadmap' grant to develop center for curing eye diseases
...ns Eye Research Institute has been awarded a grant from the National Institutes of Health to form teams of basic and clinical researchers from many disciplines to find cures for blinding eye diseases such as macular degeneration, diabetic reti...Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award
...the creation of a vaccine that will prevent people from developing AIDS -- and that will also be available...ncisco General Hospital, earned his medical degree from Cornell University Medical College and his doctorate in immunology and cell biology from The Rockefe...AAAS US Presidential Candidates' Forum
...ters are currently attracting significant interest from both candidates for the U.S. presidency and the ge..."Right now, more than 100 million Americans suffer from illnesses that one day could be wiped away with stem-cell therapy, including cancer, Parkinson's, di...New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...ion involving chromosomes 15 and 17. Their results from the RT-PCR analysis suggested that AML should be reclassified by dividing it into two groups APL with t(15-17) and t(15,17) negative AML. t(15-17) negative AML would then be sub-divided in line with the World Health Organization's histologic classif...Alzheimer's disease is not accelerated aging
...xecutive impairment. The review includes data from traditional pathological and volumetric analyses, studies of rare genetic mutations, and functional imaging methods such as positron emission tomography (PET) and functional MRI in healthy adults and individuals with Alzheimer's disease, as well as n...UT Southwestern biochemist honored with NIH Director's Pioneer Award
...edical research. Dr. McKnight the only winner from Texas is one of nine researchers in America to re...ted to receive one of the inaugural Pioneer Awards from the National Institutes of Health." One of the most significant turns Dr. McKnight took in his c...New molecular link key to cellular proteins involved in cancer progression, other diseases
...PcG) of proteins appear to abnormally switch genes from on to off, or "silence" them. The latest work reve...not involve DNA sequence and that can be inherited from one generation of cells to another. Along with ubiquitination, epigenetic modifications also include...Safety of isoflavones in dietary supplements targeted by Illinois initiative
...ies. The project is funded by an $8 million grant from the National Institutes of Health. Leading the eff...mercially available supplements. Scientists from four Illinois colleges -- Agricultural, Consumer and Environmental Sciences; Liberal Arts and Scienc...Half-million dollar landmark achieved for the Methuselah Mouse Prize
... commitments with the long term support commitment from an anonymous supporter making his donation in the ... aging, promoting not only longer life but freedom from the effects of aging-related conditions and diseases." Your support of the Methuselah Mouse Prize is...Phase II trials of second-generation antisense cancer drug planned following successful early study
...any major cancers, clusterin can stop cancer cells from dying and counters the effectiveness of chemothera...ugs work by inhibiting the production of a protein from a specifically targeted gene. As a second-generation antisense drug, OGX-011 is an advance on earlie...Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...use the bacteria incite a strong "innate" response from the immune system and at the same time sneak cance...e like a red flag to a bull -- they draw an attack from cells of the immune system -- but the strength of the immune response depends on how the flag is wav...Award winning researchers reveal potential new role for Glivec
... board of the EORTC-NCI-AACR and also won an award from the Fondation Nelia et Amadeo Barletta (FNAB)[3], ...ion to try imatinib in the treatment of DFSP arose from pioneering research from another team published in 1997[4] . This had shown that a gene called the p...Trial shows which brain cancer patients benefit from temozolomide
...st on tumour biopsies to identify who will benefit from the drug could be carried out fairly easily in any...hat the key to predicting which patients will gain from temozolomide was a gene called O-6-methylguanine-DNA methyltransferase (MGMT) which is involved in ...