No role for simian virus 40 in human pleural mesotheliomas
...t aspect of our study was that the availability of frozen mesothelioma tumor samples allowed us to search fo...tigators searched for SV40 DNA, RNA, or protein in frozen tissue samples from 71 human pleural mesotheliomas. According to the study, the methodology used by ...Genetic analysis rewrites salamander's evolutionary history
...ife," Wake said. Mueller obtained DNA samples from frozen salamander tissue in the collection of UC Berkeley's Museum of Vertebrate Zoology, and over a two-year period worked with JGI researchers to sequence the brief genomes. Once Mueller annotated the genomes, that is, identified the genes, she compared t...Dispute over life in Antarctic lake
...olar ice caps on Mars, and in the oceans under the frozen surface of Jupiter's moon Europa. Lake Vostok hit the headlines in 1996 when its extraordinary size first came to light. Spanning some 14,000 square kilometres, and reaching a depth of nearly 800 metres in parts, it has been shut away from sunlight a...Climate change could doom Alaska's tundra
...s much of Alaska, characterized by the permanently frozen deep soil layers called permafrost, few or no trees, grasses and dwarf shrubs, and an extremely short growing season. But it also supports brown bear, wolf, wolverine, caribou, arctic hare, mink, weasel, and lemming, and millions of migrating waterfo......tantially higher and that the developing eggs were frozen at a stage just prior to the completion of meiosis. The researchers then showed that by blocking the activity of another protein in the cAMP molecular signaling pathway, egg maturation could be completed. The reversible nature of the infertility blo...JCI Table of Contents, 15 July 2004
...tantially higher and that the developing eggs were frozen at a stage just prior to the completion of meiosis. The researchers then showed that by blocking the activity of another protein in the cAMP molecular signaling pathway, egg maturation could be completed in a test tube. The apparently reversible nat...Common worm provides insights into salmonella virulence
...the animals can be grown quickly. They can even be frozen and used at a later date, Aballay said. Additionally, the worm is essentially a long intestinal tract, which is also advantageous as a model for Salmonella virulence, since a primary target of Salmonella infections in mammals is the intestine. Aballa...Gene expression ratio identifies risk of recurrence in breast cancer patients receiving tamoxifen
...ceptor-positive breast cancer. They identified 60 frozen samples suitable for gene expression analysis for which clinical follow-up information was available. Of those 60 patients, 32 had remained disease-free for an average of eight years, while 28 had recurrence of their tumor or metastasis. Expression...Umbilical cord blood transplants, bone marrow transplants save lives
...try. Several cord blood banks in the U.S. store frozen cord blood samples, which can be available for transplant within days, whereas bone marrow must be obtained from a donor for a specific patient and may take months to obtain. Loyola is focusing its research on CB transplantation in adults; to date, 2...Discovery of tiny microbes in ancient Greenland glacier may define limits for life on Earth
...f these stressed and possibly damaged cells from a frozen environment that subjects them to severe conditions for long periods." Some of the cells that Miteva and Brenchley were successful in cultivating required special conditions and up to six months to form initial colonies. The researchers discovered ...Small, cold, & hungry: Ultra-small microbes from 120,000-year-old glacier ice sample
...f these stressed and possibly damaged cells from a frozen environment that subjects them to severe conditions for long periods." Some of the cells that Miteva and Brenchley were successful in cultivating required special conditions and up to six months to form initial colonies. The researchers discovered ...Baby born from sperm frozen for record 21 years
...orld record a baby born using sperm that had been frozen for 21 years. "We believe this is the longest peri...h IVF cycle, when two of the embryos that had been frozen at the start of IVF treatment were transferred to his partner's uterus. "Even after 21 years of sto...Researchers identify gene linked to sperm-producing stem cells in mammals
... methods to a strain of mice restored from embryos frozen since the early 70s. The findings, which could som...veral embryos from the 35th generation of the mice frozen at the Jackson Laboratory in Maine, the world's largest mutant mouse resource center. The UW researc...Surprising 'ultra-conserved' regions discovered in human genome
... evolved rapidly at first, then became effectively frozen in birds and mammals. "These ultra-conserved elements are long, they evolved rather rapidly, and they are now evolutionarily frozen. We don't know of a biomolecular mechanism that would explain them," Haussler said. When the researchers compared in...Analysis uncovers critical stretches of human genome
...lonize land; after that they must have essentially frozen evolutionarily. "This suggests that these were foundational innovations that were very important to the species, and since the conserved elements are different from one another, that each one was important in some particular way. It is possible that ...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
... factor receptor. Paez works with tumor specimens, frozen in liquid nitrogen, that come from the DFCI tissue bank or from collaborators at other facilities. Paez extracts the DNA and singles out the particular blocks of DNA code, called exons, where kinase mutations are likely to be found. The most exacting...NASA-inspired technology may help preserve women's future fertility after cancer treatment
...While it is possible for ovaries to be removed and frozen before cancer treatment, there is currently no reliable way to generate mature eggs once the stored tissue is thawed," said Alan J. Russell, Ph.D., director of the McGowan Institute and senior author of the study. "Finding a safe, dependable way to p...Research bank makes good use of umbilical cords
...ted with bacteria. The bank aims to have 500 units frozen to be available free of charge to local investigators, including members of the Holden Comprehensive Cancer Center at the UI. "We are currently working to provide cord blood units to all researchers that are interested in studying stem cells," Goldma...Understanding nutrition labels can lead to healthier eating
...ed to find out that there's calcium in cake mixes, frozen dinners, dry oatmeal, and soups," said Chapman-Novakofski. "And questions about calcium in food servings led to other questions about the fat content of foods, how portion sizes are determined, and the difference between weight and volume of food por......transmission x-ray microscopy, samples are rapidly frozen and need no further chemical alteration or stainin...l and Le Gros performed CT scans of whole, rapidly frozen yeast cells and obtained 3-D reconstructions at a resolution of better than 50 nanometers. "No cont...