Human stem cell research leads Science's top ten list of the best scientific advances in 1999
...ast some of the intense cosmic explosions known as gamma ray bursts are linked to the collapse of massive s...2003, whose telescopes will respond immediately to gamma ray bursts. A Flat Universe: The universe's tally of matter and energy finally added up in 1999 as......ade by strains fromtwo different genera within the gamma proteobacteria." They conclude with a call for more study saying, "Whether thestructural strategy represented by these siderophores constitutes aspecific adaptation to the seawater environment and whether it iswidespread among marine bacteria are im...Proteins that bind to sperm offer clues to male fertility and possible male contraception
...ies of HE2 epididymal proteins -- alpha, beta, and gamma -- were all regulated by the male hormone testosterone. These androgen-regulated, epididymis-specific proteins are unique, having no known homologues. A DNA database search turned up nothing similar. This would imply their function is unique, "which ...Gene defects tied to inability of cells to repair DNA damage
...tal conditions, including exposure to DNA-damaging gamma rays and to hydrogen peroxide, which generates high levels of free radicals. "These cells all showed defects in the ability to target repair to oxidative damage when it occurs in a gene," Leadon said. "This indicates that individuals whose cells l...Biomarkers: testing for alcohol consumption among women
...excessive drinking or alcohol dependence in women: gamma glutamyl transferase (GGT), carbohydrate-deficient transferrin (CDT), and mean corpuscular volume (MCV). While GGT and CDT appear to be somewhat less sensitive in women than in men, they do provide useful clinical information, especially when they......h determined these individuals' maximum and likely gamma exposure during the 10 days after the accident and...elation to increasing levels of likely exposure to gamma radiation, suggesting a possible link between dose of radiation and increased risk. However, they c...Common spices protect bacteria during irradiation
...ction to organisms against the damaging effects of gamma radiation, and also offer hope for the development of better radioprotective agents," claims Sharma. Two antioxidants in black pepper and turmeric -- piperine and curcumin -- were found to help protect the bacteria's DNA from damage by irradiation ...UCSD researchers find genetic key to puzzling congenital disease
...96 of IKK and its three sub-units alpha, beta and gamma showing that the IKK complex is responsible for controlling the body's inflammatory response, pharmaceutical companies worldwide have been working on the development of drugs to inhibit IKK. Such drugs are likely to be potent anti-inflammatory and ...New test for radiation damage to DNA developed at Brookhaven Lab
...s have long known that ionizing radiation, such as gamma rays and x-rays, can damage deoxyribonucleic acid (DNA), the genetic-code-carrying molecule that tells cells which proteins to make. The oxygen we breathe can cause damage, too. Most of the time, our bodies repair the damage we receive from everyday ...Ohio researcher receives national award
...ugh the bloodstream to active bone sites and emits gamma rays that a detector translates into an image. "The first time we saw that it was exciting, to put it mildly," said Francis....The ultimate pocket protector--radiation detection made easy
...pes of radiation-bundles of massless energy called gamma rays and tiny particles called neutrons. The devi...ium, Aryaeinejad needed to be able to measure both gamma rays and neutrons-a challenge because they interact differently with the matter around them. Gamma ...New technique will improve delivery of drugs and gene therapy for cystic fibrosis patients
...mediately after inhalation, the researchers used a gamma camera to record the deposition pattern of the radioaerosol in the lungs. The scientists also found that fine particles were far more likely to make it past the 90 degree turn in the back of the throat and go on to deposit in the lungs compared to ...UI researchers investigate regulation of immune system memory
...enerated in response to a pathogen, and interferon gamma controls the process by which most of those cells ...minated after the infection is cleared. Interferon gamma also affects which parts of the pathogen cause the immune system to respond. The roles of these mol...Gene therapy for muscular dystrophy
... that had been engineered to lack a protein called gamma sarcloc-glycan (gsg) in their muscles, which is the same protein that is missing in muscluar dystrophy (MD). The researchers administered the protein to both groups of mice by enclosing the gsg in the recombinant adeno-associated virus (rAAV) a comm...Neuronal choir hums in unison to rivet brain's attention
...s conspicuously synchronized their activity in the gamma (40-90 hz) range, which roughly corresponds to the hum of an electrical power outlet or fluorescent light. Meanwhile, neurons activated by features of the distracters, in effect, continued to speak with disparate voices. The researchers suggest tha...Scientists discover a genetic cause for severe complication of the autoimmune disease lupus
...other gene, which codes for a receptor known as Fc gamma receptor IIIA, the results were dramatic. Lupus patients possessing the weaker-binding allele had twice the risk of developing nephritis, and more than four times the risk of developing severe nephritis - but only if they were Caucasians. Non-Caucasi...Immune system helps prevent tumors after all
...hers have found evidence that both lymphocytes and gamma interferon (IFNg), a protein produced by certain lymphocytes, might play important roles in tumor prevention. So Schreiber and colleagues decided to explore further. In this current paper, they used a strain of mice that completely lacked functional...Benefits from Alzheimer's plaque-producing reaction? Science study proposes role in gene expression
...or the first time, provide a biological reason for gamma cleavage, which liberates beta amyloid fragment that causes Alzheimer's disease," said Sdhof. The researchers took their lead from another protein, called "Notch," which is found in the same part of the cell as APP and is cleaved by a related enzy...NTP plans to look at common viruses, radiation, cooking by-products for new carcinogen report
... are common throughout the world. X-radiation and gamma radiation, used in medical diagnosis and treatment, and produced in the use of atomic weapons. Neutrons, which may affect patients getting neutron radiotherapy and the passengers and crew of aircraft, which are naturally bombarded by the particle. ...Aggressive tumor cells leave a trail in their environment that affects the spread of cancer
...ic extracellular matrix molecule called laminin 5, gamma 2 chain," Hendrix said. "We found that this particular laminin is produced almost exclusively by aggressive, compared to poorly aggressive, melanoma cells. Furthermore, two specific MMPs (MMP-2 and MMP-14) were also found to be at higher levels in th...