Weizmann institute scientists solve the 3-D structure of the enzyme involved in Gaucher disease
Rehovot, Israel -- June 2, 2003 --An interdisciplinary team of Weizmann Institute scientists has solved the three-dimensional structure of an enzyme called glucocerebrosidase. Mutations occurring in this enzyme cause Gaucher disease, a genetic illness that mainly affects Ashkenazi Jews. The Institute study, published recently in EMBO Reports, may lead to the design of effective new therapies for...Potential new treatment for Gaucher disease developed by scientists at Scripps Research Institute
A group of scientists at The Scripps Research Institute (TSRI) have developed a compound that could potentially be used as a new treatment for Gaucher disease, the most common genetic disorder affecting Jewish people of Eastern European ancestry. Although not tested in humans, the compound has shown great promise in human cell lines cultured from patients who suffer from the disease.... ...Patien...