A test case for DNA barcodes to identify species
...t a short stretch of genetic code from a reference gene is sufficiently characteristic of one species to d...nd that comparisons of sequence variations in that gene can also reveal evolutionary relationships among species. Hebert and colleagues tested the effective...Evidence builds for potential new cancer drug target
...nother step in the process of validating the c-myb gene as a potential target for new cancer drugs," said ...ersity School of Medicine. Knowing that the c-myb gene played a role in the spread of leukemia, the researchers wanted to determine the gene's normal funct...Hidden diversity: DNA 'barcoding' reveals a common butterfly is actually 10 different species
...s in a small signature and standardized portion of gene called cytochrome c oxidase I, common to all life....ode of Life Database can determine patterns of COI gene variation within a given group of specimens. If the specimens in question differ by more than a few...DNA barcode finds four new bird species
...y paper, proposed that a short DNA sequence from a gene found in all animals can be used to identify speci... The technique depends on analyzing a portion of a gene called cytochrome c oxidase I (COI) that is found in the power sources of cells of all animals. Most...Marijuana use could cause tubal pregnancies
...binol (THC). In pregnant mice that lacked the gene for the receptor, or in which the receptor was blo... reach the uterus. This strain of mouse lacks the gene for the CB1 receptor. When the researchers gave a drug that blocked CB1 in normal mice, they observe...Master of antimalarial resistance
A malaria parasite gene called pfcrt, already confirmed as the culprit beh...est that previously unknown mutations in the pfrct gene are associated with Plasmodium falciparum's resistance to halofantrine and amantadine. The two drugs...No role for simian virus 40 in human pleural mesotheliomas
...mors have lost both copies of the tumor suppressor gene designated p16 or CDKN2A, and this led us to ask whether SV40 infection might be a possible mechanism in the remaining 20 percent," said Marc Ladanyi, M.D., Director, Diagnostic Molecular Pathology Laboratory,and the study's senior author. "But inste...Researchers ID chlorophyll-regulating gene
...f California, Berkeley, have identified a critical gene for plants that start their lives as seeds buried ...he journal Science, the researchers describe how a gene called phytochrome-interacting factor 1, or PIF1, affects the production of protochlorophyll, a prec...'Gene chips' research in cotton could lead to superior variety
...y the National Institutes of Health on translating gene expression mechanisms using plants as a model syst...ays have broad applications in studying changes in gene expression and genomic structure in many biological contexts, including genetics, physiology, develo...Enzyme maintaining chromosome ends is linked to bone cancer recurrence, decreased survival
...e. "Overall, our results indicate that telomerase gene expression is associated with an unfavorable outcome for children being treated for osteosarcoma," said Jeffrey S. Dome, M.D., associate member in Hematology-Oncology at St. Jude. Dome is senior author of the JCO report. Robert P. Sanders, M.D., a St...Cannabis may help combat cancer-causing herpes viruses
... the spread of gamma herpes viruses by targeting a gene these viruses all share called ORF50. Dr. Medveczky emphasized that more studies are needed. "We have not evaluated the effect of THC in an animal model yet so we do not recommend people start using pot to prevent or treat cancers." In fact, Dr. Mev...A novel, safer strategy for regulating gene expression
...a novel, elegant, and safer system for controlling gene expression turning genes on and off as needed th...iving a drug. Potentially, with this technique, a gene could even be activated by natural conditions in the body for example, in a diabetic patient, a ri...Study explores gene transfer to modify underlying course of Alzheimer's disease
...e successfully initiated a new technique that uses gene therapy to deliver nerve growth factor into region...his study. The new technique uses CERE-110 as the gene therapy agent. CERE-110 carries the Nerve Growth Factor (NGF) gene encased in a harmless viral coati...The book opens on the first tree genome
...sequence tag (EST) resource necessary for accurate gene prediction. The total investment in the Swedish Po...he trick will be in figuring out how these similar gene sets have been customized and redeployed in poplar to generate a large woody plant instead of a smal...NSF awards 22 new projects for plant genome research
...ff, a step toward providing tools for manipulating gene expression in maize and other crop plants. Univers...s on using experimental approaches to define every gene -- perhaps as many as 60,000 -- in the recently completed rice genome....$2.7 million grant to support creation of virtual zebrafish atlas
... compare to the zebrafish used in their studies of gene functions and disease. The comparisons to the imag... individual genes in vertebrates and the timing of gene expression during development in the context of a whole, living organism," Cheng said. "Strong simil...Experimental drug shown to block mutant protein causing blood disease
...en pieces of the chromosome that carries the FGFR1 gene join together abnormally. The findings suggest, the authors write, that PKC412 may be effective in treating MPD, as well as other diseases and cancers where mutant FGFR1 is the culprit. These include human skeletal disorders such as Pfeiffer syndrome...'Fossil genes' reveal how life sheds form and function
...bsent from all three, with only a single remaining gene marking the pathway like a faded signpost. "Evolution repeats itself," Carroll says. "What we see is that three or four times, these genes have been junked in different species. The process of sweeping these genes away is more complete in these other...Research suggests new avenue for stopping, preventing colon cancer
... the pain and inflammation of arthritis, but COX-2 gene expression is also elevated in a variety of malignancies including colorectal tumors. COX-2 generates several potent, hormone-like substances called prostaglandins that play a role in a wide variety of physiological functions. One of them, prostagla...Loss of the neuronal adhesion protein d-catenin leads to severe cognitive dysfunction
...cations that disrupt the function of the d-catenin gene correlate with the severity of mental retardation in Cri-du-Chat Syndrome; in addition, d-catenin is known to interact with Presenilin 1, the protein most often mutated in Familial Alzheimer's disease. Despite these observations, until now there has...