Tag: "gene" at biology news
Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
...y Brook University will collaborate to study a new gene
and cell therapy that may ultimately provide bette...expands the possibilities to enhance research into gene
therapy," said Gail Habicht, Ph.D., Stony Brook vice president for research. Research will be cond...
University of Pittsburgh receives $10 million grant for head and neck cancer
...apeutic vaccine that targets the tumor-suppressing gene
p53. A critical gene
involved in the development of many cancers, p53 is damaged in most cancers and this damage is corre...
Researchers uncover secrets of immune system's munitions factory
...ine deaminase (AID) triggers mutations of antibody gene
segments to produce an assortment of antibody prot... highly specific process that involves recombining gene
segments that encode the part of the antibody molecule that direct it where to take its antigen carg...
Trojan Horses, xenon imaging and remote controlled genes
...like a switch in order to find out the nature of a gene
by what happens when it does not work."...
UCSD biologists develop 'super-endurance' strain of mice
...valent of Olympic endurance athletes by deleting a gene
that allows mammalian muscles to switch from aerob... students discovered that "knocking out" the HIF-1 gene
in the white blood cells of mice limited the tendency of the cells to rush en masse to areas of infe...
Improving crops without genetic modification natural variation holds the key
...t traditional breeding is limited by the available gene
pool of a cultivated plant species and eventually ...he incorporation of a single transgene--that is, a gene
taken from a different species--with the hoped-for response. Biotech-based investigations and applic...
No longer just for biology, RNA can now be built into 3-D arrays
...affolding on which diagnostic chips, tiny sensors, gene
delivery vehicles and other nanoscale devices will... into nanodevices for such applications as drug or gene
delivery, gears for nano-equipment, and intricate arrays and chips for diagnostic devices, sensors a...
Engineering endurance: The future of the Olympics?
...to produce ATP. When blood oxygen levels drop, the gene
transcription factor hypoxia-inducible factor 1 (H... exercise, the normal mice had increased levels of gene
transcripts and enzymes involved in glucose transport and metabolism. In the mutant mice, expression...
Length of sex act in flies dictated by genetics
...clock genes. In other studies over many years, the gene
period, as well as other "clock" genes, have been extensively explored. Giebultowicz has found, for instance, that constant exposure to light can "switch off" the biological clock in the male gypsy moth and cause them to become sterile. However, when...
Anticancer drug zebularine specifically targets tumor cells
...-is better at inhibiting cell growth and promoting gene
expression in cancer cells, notes Peter Jones, Ph....e development of cancer. If methylation silences a gene
that normally would control cell growth or prompt the cell to commit suicide, then the cell will gro...
Genetically-engineered 'marathon mouse' keeps on running
...archers were exploring the effects of altering the gene
for a protein called PPAR-delta -- a master regula...t was especially surprising that altering a single gene
produced such wide-ranging physiological changes in the mice. According to Evans, most physiologists...
Researchers find clues about how antibodies specialize
... kinds of specialized antibodies through selective gene
mutations, while being protected from random mutat...from which antibodies are made. Mutations in these gene
segments to the so-called variable regions -- give our B cells the ability to make unique, speciali...
Breakthrough in understanding of hereditary disease of lymphatic vessels
...stichiasis (LD), which is caused by mutations in a gene
called FOXC2. The team found that the lymphatic ve...of lymph. This is the first study that describes a gene
critical for the formation of lymphatic valves, and regulation of the interaction between lymphatic ...
In gene regulation, small is beautiful
...olecules to take a big step forward in controlling gene
activity. Scientists have been trying for some tim...develop molecules that mimic natural regulators of gene
expression. These natural regulators, called transcription factors, prompt particular genes to be ac...
Genetic clues found for common congenital brain disorder
...short for Zinc finger in cerebellum 1, was a known gene
that played a role in development of the cerebellu...order. Mice with one dysfunctional copy of either gene
had mild anatomic abnormalities but no behavioral changes. But about 15 percent of the mice that ha...
Penn scientists identify novel pathway in aneurysms
...asthma is activated. Mice without the inflammation gene
were protected from aneurysms. Colin D. Funk, PhD...heir progression and eventual rupture," he adds. A gene
for the 5-lipoxygenase-activating protein, which is required to synthesize leukotrienes, potent infl...
Virus known for its photo ops makes its movie screen debut
...ould reveal secrets of viral infection and improve gene
therapy techniques, according to a Purdue Universi...dy could bring us one step closer to using it as a gene
therapy vehicle." Gene therapy using T4 remains a distant possibility, however, and Rossmann said th...
...al differences between the DNA sequence of the mlo gene
from resistant and susceptible plants. Thus, the p...Panstruga and Paul Schulze-Lefert discovered a mlo gene
fragment which occurs in several repeats in the genome of the mutant. About ten adjacent repeats cou...
Illustrated guidebook published for Chinese biomedical scientists and students
...ang, describes it as a wonderful tool for learning gene
technology. And we are fortunate to have partnered with a leading Chinese publisher, Science Press of Beijing, to bring the book to the many scientists in mainland China who wish to improve their English skills. The publication of this book is one o...
Heartless worms hold clues to cardiac arrhythmias, sudden death
...ent, Yang was able to detect a variant in the KCR1 gene
that occurred more often in control patients -- those who did not develop the syndrome. "We suspect that this variant is protective, that patients who have it are somehow more protected against drug block of HERG compared to patients who don't have ...
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