Tag: "genetically" at biology news
In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...uencing motivational and metabolic components of a genetically
determined set of central systems. While the data suggest that these metabolic adaptations might hinder successful weight maintenance, it should not imply that successful weight maintenance is unachievable. Even with the increased intake of carbohyd...
Purdue yeast makes ethanol from agricultural waste more effectively
... to the biotechnology company Iogen Corp. Purdue's genetically
altered yeast allows about 40 percent more ethanol...s group became the first in the world to produce a genetically
engineered Saccharomyces yeast that can effectively ferment both glucose and xylose....
Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice
...ock up on potato chips and ice cream just yet. The genetically
altered mice are leaner than normal mice, but they...e studying the effect of Wnt proteins on mice with genetically
induced obesity. They also plan to explore the effect of Wnt signaling on the development of osteobl...
Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...cording to Ahrens. The animals studied were nearly genetically
identical and reared in the same environment -- factors that cannot be controlled in human studies. And the imaging technology, magnetic resonance microscopy, allows high resolution, 3D imaging in the intact, tiny mouse brain. "The finding that sp...
Noah's modern ark: The role of ART in conserving endangered species
...is not simply to produce an offspring, but rather, genetically
valuable offspring. We are trying to avoid inbree...h so that we can begin to help conservationists to genetically
manage rare populations."...
Scientist honored for studies of genetic influence on chemotherapy, tumor development
...nship between cancer mutations and the response of genetically
defined tumors to therapy. Previously, Lowe was honored by the AACR with its 2001 Award for Outstanding Achievement in Cancer Research, for his work on the p53 tumor suppressor gene; and, in 1993, he received an AACR Scholar-in-Training Award o...
Joslin researchers identify key molecule in Type 1 diabetes progression
...n studied insulitis lesions in a certain strain of genetically
engineered mice called BCD2.5 mice. These mice develop insulitis, but a very respectful form, such that diabetes does not follow until months later, or, in some, never. The researchers discovered that both effector and regulatory T-cells co-existed...
Inadequate vaccines can help breed more vicious malaria strains
...e to the syringe" - or the mosquito - are probably genetically
equipped to stay ahead of the advancing immune system. Since the virulent strains showed no problems transmitting infection to new hosts, it's likely that such strains would spread throughout an immunised population. "Many questions remain, but the...
Therapeutic cloning may be permitted at Newcastle University
...r injury. Cells derived from ES cells may often be genetically
different from the patient, and transplanted cells...use nuclear transfer to derive stem cells that are genetically
identical to those of a patient. In this case the stem cells and cells derived from them would not b...
UNC scientists uncover crucial mechanism for blood vessel development
... vessel formation using mouse embryonic stem cells genetically
engineered to lack the flt-1 gene and then induced to become endothelial cells. Mutant and normal embryonic stem cells were additionally engineered to express the green fluorescent protein. This "marker" allows fluorescence microscopy to visualize li...
How genes get us wired
...hin facial muscles. Because mice are so similar genetically
to other mammals, the findings in mice likely hold true in humans, he adds. Benjamin Arenkiel, a human genetics doctoral student who conducted the research under Capecchi's supervision, says the study shows "Hoxb1 is involved in generating the ner...
Genetic modification in mice lowers cholesterol and homocysteine by half
Canadian scientists report that mice genetically
altered so as to lack either of the two different ...ibutes the other 30 percent. When the researchers genetically
altered the mice so that their livers lacked either the CT or the PEMT pathway, the mice appeared no...
Changes to insect-seeking calls of horseshoe bats may drive new species formation
...on one side of the mountain would begin to diverge genetically
from those on the opposite side. Eventually, the two populations of the bat species would become sufficiently different to qualify as separate species. In their study, Kingston and Rossiter found that large-eared horseshoe bats ( Rhinolophus philipp...
Drunken worms reveal a genetic basis of alcohol response
...ubject of massive genetic study by scientists, and genetically
distinct strains are available from around the world. In their experiments, Davies and his colleagues exposed two wild strains of worms -- one from England and one from Hawaii to alcohol and compared how they showed "acute tolerance" when fir...
UF researcher: New low-carb potato to debut in January
... anything that's now on the market, and it's not a genetically
engineered crop," Hutchinson said. "When it comes to beautiful potatoes, this one is a real winner for growers and consumers." Hutchinson, a potato expert, said five seasons of evaluation in his research program at UF show the tuber ca...
Lab mice rescued from Type 1 diabetes via dendritic cell-assisted therapy
...esearch used a special source of T cells from mice genetically
altered to have a majority of cells directed to the islets. Now Tarbell will extend the strategy into mice with a normal repertoire to see if the dendritic cells can coax the suppressor cells -- here at a much lower frequency to begin with -- to expa...
Gene therapy tested to protect bone marrow during chemotherapy
...edure. Instead, the intent is to "select" for the genetically
altered cells with intermittent outpatient chemoth...d to other therapies. In one patient, evidence of genetically
altered cells was documented by molecular analysis in both the blood and marrow six weeks after the ...
Biologists discover nerve activity, not just genetics controls kinds of neurotransmitters produced
...urotransmitters used by different nerve cells were genetically
programmed into the cell. "If you were to ask neu...use everyone thought neurotransmitter identity was genetically
programmed. Our results show that by altering neural activity, you can change the identity of the ne...
Biology of aging
...and four other Brown researchers created a line of genetically
altered flies which had dFOXO a protein controlled by the fly equivalent of insulin inserted into the genetic material of fat cells near their brains. Some flies were fed mifepristone, a chemical copy of progesterone. This hormone activated a switc...
RNAi delivery system crosses blood-brain barrier to target brain cancer
... the delivery packets--called liposomes--deposit a genetically
engineered non-viral plasmid in the brain cancer cells. The plasmid encodes a short hairpin RNA (shRNA) designed to interfere with the expression of the epidermal growth factor receptor, EGFR, a potent proponent of tumor cell proliferation. The use o...
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