'Noisy' genes can have big impact
... in cells -- or people for that matter -- that are genetically identical. The researchers, HHMI investigator Erin K. O'Shea and colleague Jonathan M. Raser, both at the University of California, San Francisco, published their findings May 27, 2004, in Science Express , the online edition of the journal Scien...Friendly bacteria block HIV infection
...ack no matter whether the virus particle itself is genetically altered. "While studies have been done so far only in the laboratory, we believe this work opens up new possibilities for preventing the transmission of HIV through mothers' milk," says Tao. "Unlike standard retroviral drugs, which are too toxic for...Genes appear to play a role in development of chronic obstructive pulmonary disease
...isease specialist reports that some smokers may be genetically predisposed to chronic obstructive pulmonary disease (COPD). Jill Ohar, professor of pulmonology and critical care medicine at Wake Forest Baptist, presented her findings at the 100th International Conference of the American Thoracic Society in Orlan...Indoor mold, building dampness linked to respiratory problems and require better prevention
...is also is associated with indoor mold exposure in genetically susceptible people. Damp conditions and all they entail may be associated with the onset of asthma, as well as shortness of breath and lower respiratory illness in otherwise healthy children, although the evidence is less certain in these circumstan...Study shows that genes can protect kids against poverty
... UW-Madison and King's College London. Given these genetically influenced capabilities, Moffitt adds, "We reasoned that they might help poor children in their struggle to overcome their lack of economic advantages." Results from the study show that genetic makeup does play a part in resilience. According to the ...Small trial shows daclizumab add-on therapy improves MS outcome
...tients also received 7 treatments of daclizumab (a genetically engineered human antibody that blocks the interleukin-2 receptor on immune cells) administered intravenously at 2-week, and later, 4-week intervals. Ten patients showed a reduction in both the severity and number of brain lesions as demonstrated by m...Many scientists believe the dog genome holds information that will benefit human health
...ream because each pure breed represents a group of genetically similar animals that have descended from only a fe...y than they would in a population of unrelated, or genetically dissimilar, animals. In addition, because most breeds were developed within the last 300 years-consi...First genetic comparison of purebred domestic dogs produces surprises
...or finding was that the different breeds are quite genetically distinct," said Kruglyak. "The dogs of a particula...t of the breeds are quite recent and were formally genetically isolated only in the nineteenth century, with the advent of breed clubs and breed standards," said K...A new way to kill cancer: SLU research shows viruses can destroy lung, colon tumors
ST. LOUIS - A genetically engineered virus can selectively kill cancerous cells in the lung and colon while leaving healthy cells intact, according to new research published today in Cancer Research by William Wold and colleagues at Saint Louis University School of Medicine. ...Research into cetacean reproduction leads to birth of killer whales by artificial insemination
...ical facilities numbers only 48, mostly in small, genetically isolated groups. Since 1985, natural breeding of captive killer whales has led to 27 births, but natural breeding sometimes requires moving animals between facilities. Robeck and his team point out that artificial insemination capabilities will hel...Functional genomics enables easy target identification and drives drug discovery
... functional genomics opens up the possibilities of genetically demarcating patients and predicting individual responses to drugs. This permits customized medications and dosages that improve treatment safety and efficacy in areas such as neuropsychiatry, cardiovascular medicine, endocrinology, and oncology. The ...Domesticated tree crops may be the 'future of forestry'
...atural resources. "I'm not suggesting that we have genetically engineered trees growing in all our national forests," he said. "But this kind of technology could allow us to increase our yields and create tailor-made trees to meet society's demands for forestry products without encroaching on wilderness areas." ...Parent-offspring conflict in the evolution of vertebrate reproductive mode
... arises because a mother and her fetus are related genetically by only one-half, such that fetuses are subject to natural selection to take more resources from the mother than she is selected to provide. David Haig showed in 1993 that parent-offspring conflict can explain many puzzling features of human pregnanc...National Cancer Gene Therapy Foundation gives $4.0 million in research grants
...s of the body. Dr. Reilly and his lab are using a genetically modified tumor cell as the vaccine. The target of the vaccine is called HER-2/neu (neu), a cancer-related gene that is overexpressed in about one-out-of-three breast cancers. Using a specially developed laboratory animal model, this group has demon...Mexican farmers effectively cultivate phenotypic diversity in maize
...to better assessment of the risks from a spread of genetically modified transgenic-corn varieties that might possibly be introduced into Mexico among traditional local landraces. Such work could therefore help provide some answers for the public debate which for many years has been running on this issue (3)....Biological cause of one form of blindness identified by SLU researchers
...use of one form of retinitis pigmentosa, a type of genetically inherited blindness. The research, which will be published Tuesday in the April 27 Proceedings of the National Academy of Sciences (PNAS), opens the door to the development of new treatments. The research was based on genetic information provided...Gene defect linked to premature aging
...forms of the gene occur in acute leukemias. Using genetically engineered mice, Arceci's team knocked out part of the "core engine" of the PASG gene, decreasing methylation throughout the genome and allowing the wrong genes, particularly those associated with premature aging, to be active all the time. The resu...Tracking cystic fibrosis with mice
...isease in mice. Marcus Mall, a medical researcher, genetically modified mice to generate the typical symptoms of ... therapy for humans can also be studied with these genetically modified mice. To study the effect of the defective "cystic fibrosis transmembrane conductance regul...Cellular problems found behind complex obesity syndrome
...ormal appetite controls. However, experiments with genetically engineered mice will be necessary to know for sure, he says. Although the work is far from revealing an anti-obesity "magic bullet," the researchers, also from Simon Fraser University in Canada and the University College London, say it does point......Lovitch and others in Unanue's lab have produced a genetically altered mouse that only has type B T cells. They plan to study these mice to determine whether normal inflammation can provoke an autoimmune reaction in the T cells, leading to conditions similar to diabetes....