Tag: "genetically" at biology news

Mastectomy dramatically reduces breast cancer risk among women with BRCA1/2 mutations

...reduces the risk of breast cancer in women who are genetically predisposed to the disease," said Dr. Barbara Weber, MD, Professor of Medicine and Genetics at the University of Pennsylvania, an investigator in the Abramson Family Cancer Research Institute, and senior author of both studies. "Women undergoing thi...

UNC study may improve gene therapy safety

...senger can be as important as the message: Viruses genetically engineered for use as delivery vehicles for transf...deno-associated virus, or AAV. These viruses, when genetically engineered, have shown particular promise in laboratory studies as gene transfer vectors and have be...

USC researchers produce a hairier mouse

...in the number of hair follicles in the skin of the genetically modified mouse. And that is, indeed, what they saw. Not only was the fur of these mice thicker, with hair follicle density increasing by as much as 80 percent in the transgenic mice, but the transgenic mice also grew more whiskers than normal mice, w...

Purdue scientists: Genetically modified fish could damage ecology

...omosomes to make the animal grow larger. While the genetically modified fish will be bigger and have more success... entirely. "Ours is the first demonstration that a genetically modified organism has a reproductive advantage over its natural counterpart," said Howard, a profess...

Schering-Plough scientists identify protein essential for cholesterol absorption from intestine

...search, studied "gene knockout" mice that had been genetically engineered to lack the NPC1L1 protein. Davis and his colleagues found that the knockout mice absorbed 70 percent less cholesterol from their diets than did normal mice, demonstrating that NPC1L1 is a critical component in the cholesterol absorption ...

Celiac disease is a risk factor for schizophrenia

...oportion of individuals with schizophrenia who are genetically prone to celiac disease but have not been diagnosed with it," said Dr. Eaton. ...

Study in worms shows how genes linked to complexity in animals

...udied." Learning how C. elegans differs genetically from its relatives could give researchers insight into how organ systems in more complex animals evolved. One example could be the human kidney. "Changes in gene function are at the heart of evolutionary complexity," Chamberlin said. "The ...

Discovery could lead to better treatment for cryptosporidum infections

...yptosporidiosis. One intriguing possibility may be genetically engineered model parasites created to express C. parvum genes. This could allow a completely new approach to screen efficiently for potential drug candidates, which is one of the next goals of the team at UGA....

Improved medical treatment of serious heart problems focus of UH-led group

... complications. The group's new products include genetically engineered cartilage cell coated stents (stent gra...l treatment of AAA. Rosenstrauch will finish with genetically engineered cartilage cell-coated stents for the treatment of coronary artery disease....

Athletics, genetic enhancement and ethics

...uscle mass and strength reported in the exercised, genetically enhanced rats. Their findings support the hypothes...ch, in turn, led to increased mass and strength in genetically enhanced and exercised muscle. The scientists also report that muscles from rats with genetically el...

Possible mechanism for link between diabetes and Alzheimer's disease discovered

...n, M.D., of Joslin Diabetes Center in Boston, used genetically altered mice called Neuronal Insulin Receptor Knockout (NIRKO) mice, which are missing insulin receptors in their neurons (brain cells). Previously, using these NIRKO mice, Bruning and Kahn had shown that neuron-specific insulin resistance could cont...

University of Minnesota professors to speak at symposium on international trade

...bryos in the laboratory that allows researchers to genetically engineer corn and other crop plants. He chaired the 1996-98 White House Commission that developed a national plan for plant genome research and heads a National Science Foundation (NSF)-funded project to sequence the corn genome as part of NSF's Plan...

Studies suggest brain injury results from developmental exposure to alcohol, anesthesia, and lead

...pain during labor. Olney said that nerve cells are genetically programmed to commit suicide if they fail to make synaptic connection on time. Alcohol and anesthetic drugs interfere with the brain's neurotransmitter systems, thereby retarding the formation of synaptic connections. This automatically activates a...

Nanoparticle probes are destined for major new role in medical diagnostics and drug delivery

...bombs" to deliver controlled amounts of drugs into genetically classified tumor cells. "Nanomedicine is a priority in the recently released new Roadmap of the NIH," Dr Nie points out. "We expect Emory and Georgia Tech to be institutional leaders in nanomedicine."...

Unlocking the genetics and evolution of the dog could prove beneficial for humans

...ic loci for the fox, they know that trade-offs are genetically controlled, or inheritable in the fox. The fact that the fox and dog have similar trade-offs tells researchers that this type of genetic mechanism was present in a common ancestor that eventually gave rise to the modern canine family in which the fo...

Small amounts of alcohol or anesthetics may damage the developing brain

...w weeks after the animal is born. Nerve cells are genetically programmed to commit suicide if they fail to make synaptic connections on time. Alcohol and anesthetic drugs interfere with the brain's neurotransmitter systems and with the formation of those synaptic connections, automatically activating a signal w...

Gates Foundation commits $82.9 million to develop new tuberculosis vaccines

... enhanced version of the BCG vaccine that has been genetically engineered to stimulate a stronger immune response. Aeras began a Phase I clinical trial of rBCG30 in the U.S. in January 2004. The second, a fusion protein, is a new vaccine that combines two proteins from the TB pathogen that are primary targets ...

Money talks: Concern for biodiversity pressed on boardrooms by new breed of fund managers

... shed services, the advent of labeling schemes for genetically modified food products, the emphasis of global env...environmental management systems, human rights and genetically modified organisms (GMOs) are increasingly common social screens, with corporate governance expected...

Destructive wizardry of Ozz-E3 ligase appears key to building skeletal muscles in embryos and adults

...scoveries using muscle tissue from both normal and genetically modified mice. The researchers showed that the delicate balance between accumulation and removal of β-catenin at a specific cellular site, the sarcolemma the membrane covering each muscle fiber is achieved by the activity of the Ozz-E3 ligas...

Research points in new direction for cancer clues

...cular protein or signaling pathway is to develop a genetically engineered "knock-out" mouse that does not express the particular protein in question. But TGF beta and its receptor are so critical to mammalian development, mice bred to eliminate this signaling pathway in all cells die as embryos. To eliminate t...

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