Pack-MULEs are toting a new look at plant evolution
...cold responses in a plant. In 1998, MSU molecular geneticist Michael Thomashow and his associate found that increasing a plant's expression of a specific regulatory gene helps throw the plant into cold-coping mode, beefing up its defenses against freezing. Her familiarity with Thomashow's work raised a flag. ...Brain's reward circuitry revealed in procrastinating primates
...to temporarily knock it out of action. Molecular geneticist Ginns, who recently moved from NIMH to the University of Massachusetts, adapted an approach originally used in mice. He fashioned an agent (DNA antisense expression construct) that, when injected directly into the rhinal cortex of four trained monkey...Genetic mutation found that is major contributor to type 1 diabetes
...t more reactive," said Dr. Cong-Yi Wang, molecular geneticist and co-senior author. Dr. Wang and his research team found that when that mutation encounters an environmental trigger, such as a bacterial or viral infection, it throws off the usual well-balanced activity of the immune system, initiating an autoim...Natural selection at work in genetic variation to taste
...ne that allows us to taste or not taste PTC," said geneticist Stephen Wooding, Ph.D., corresponding author on the study and a post-doctoral fellow at the Eccles Institute of Human Genetics at the University of Utah School of Medicine. Today, the ability to taste, or not taste, the compound influences what peopl...Fox Chase Cancer Center's Alfred Knudson Jr. named 2004 Kyoto Prize winner
...ch staff at Fox Chase Cancer Center since 1976. A geneticist and physician, Knudson is internationally recognized for his "two-hit" theory of cancer causation, which explained the relationship between the hereditary and non-hereditary forms of a cancer and predicted the existence of tumor-suppressor genes that...UW-Madison scientists find a key to cell division
...cientists led by a University of Wisconsin-Madison geneticist was announced in today's edition of the journal Science. The discovery promises a better understanding of the role of cell division in the growth and development of all organisms and, critically, of abnormal cell division, when the key proteins fail...Researchers identify gene linked to sperm-producing stem cells in mammals
... the University of Ohio. Green, a well-known mouse geneticist who died several years ago, had several embryos from the 35th generation of the mice frozen at the Jackson Laboratory in Maine, the world's largest mutant mouse resource center. The UW researchers contacted The Jackson Laboratory for the embryos, and...Researchers confirm genetic link between hereditary breast and prostate cancer
...utations," said Noah Kauff, MD, a gynecologist and geneticist at Memorial Sloan-Kettering and a co-author of the study. The study authors point out that the age of onset of prostate cancer in men carrying these mutations was no different than in most men diagnosed with prostate cancer ...Immunity gene predicts severe adverse drug reaction
...ording to a Duke University Medical Center medical geneticist and collaborators in Taiwan. The sometimes fatal condition is characterized by a blistering rash that can lead to detachment of the skin and inflammation of the gastrointestinal and respiratory lining. More than 100 drugs -- including antibiotics, NS...Stanford study questions identity of alleged Romanov bones
...rensic Science Service and Pavel Ivanov, a Russian geneticist from the Engelhardt Institute in Moscow, conducted a battery of experiments supporting the hypothesis that the Ekaterinburg bones belonged to the Romanovs. The team performed DNA-based sex testing and analyzed short sequences of DNA from the nucleus...Desert science center aims to bridge rift between Jordan and Israel
...ere brought in as academic partners, said Stanford geneticist Marcus W. Feldman, the Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences. For the past three years, Feldman has chaired the academic planning committee of the foundation and made several trips to the Middle East...Stanford launches public lecture series on genomic medicine
...t 5 p.m. The lecture will be delivered by Stanford geneticist Marcus Feldman, the Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences. Feldman will be introduced by Paul Ehrlich, the Bing Professor of Population Studies in the Stanford Department of Biological Sciences and a...BRCA mutations do not increase risk of colorectal cancer
...er," says Stephen B. Gruber, M.D., Ph.D., a cancer geneticist in the U-M's Comprehensive Cancer Center. "The good news in our study is that they don't have to deal with an increased risk of colorectal cancer, as well." Results of the study will be published in the Jan. 7 issue of the Journal of the National Ca...Researchers find key gene in production of egg and sperm
...rs of the paper include Inna Golubovskaya, a maize geneticist and visiting scientist in UC Berkeley's Department of Plant and Microbial Biology, who discovered the phs1 mutant in a North Dakota corn field; Robert Meeley of Pioneer Hi-Bred, who used reverse genetics technologies to identify additional phs1 mutan...Chimp vs. human DNA: what's in the 1% difference
... analysis would be informative," says evolutionary geneticist Andrew G. Clark, Cornell professor of molecular biology and genetics. "But we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurring in human ancestors." Those genes are involved in the sense of sme...Lifestyle accounts for difference in chimp, human genome
... analysis would be informative," says evolutionary geneticist Andrew G. Clark, Cornell professor of molecular biology and genetics. "But we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurring in human ancestors." Those genes are involved in the sense of sme...'HapMap' scientists provide detailed plans
...ational HapMap Consortium. Chakravarti and Hopkins geneticist David Valle were members of the initial National Institutes of Health planning group on Populations and Ethical, Legal and Social Issues. The Johns Hopkins HapMap effort is funded by the National Institutes of Health. ...Discovery of brain disorder gene paves way for genetic test
...symptoms, as are their future children," said Duke geneticist Douglas Marchuk, Ph.D., who led the study. "This is an example where genetic testing can make a tremendous impact on the care these families receive." Physicians currently diagnose patients only when lesions are found on an MRI scan after symptoms de...Easily paralyzed flies provide clues to neurodegeneration
MADISON - With a slight tweak of temperature, geneticist Barry Ganetzky's flies drop like, well, flies. For 25 years, Ganetzky has been identifying, breeding and studying a raft of fly mutants that, when exposed to minor temperature change, become completely paralyzed. The flies, which qui...New findings implicate cell size controls in a variety of diseases
...ute colleagues. Guan wants to collaborate with LSI geneticist David Ginsburg on developing mice that mimic the genetic disorders so that further study can be done on the biochemical chain of events. And Guan wants to connect with LSI cell biologist Daniel Klionsky to look for parallels between this mammalian ve...