RNA lariat may tie up loose ends to decades-old mystery of retrovirus life cycle
...aid Patrick Dennis, program director for microbial genetics at theNational Science Foundation (NSF), which supported the research. "The RNA lariat provides a plausible mechanism for a key step that has remained a mystery since the process ofreverse transcription was first presented almost 35 years ago." The ...Gene affecting bone mass, osteoporosis risk identified
...or step forward." Gary Peltz, M.D., Ph.D., head of genetics at Roche Palo Alto and a study co-author, said: "The study demonstrates that mouse genetic discoveries can lead to new opportunities for human therapeutics. It also demonstrates how the rate of genetic discovery was accelerated by coupling genetic an...BRCA mutations do not increase risk of colorectal cancer
...assistant professor of internal medicine and human genetics in the U-M Medical School and an assistant professor of epidemiology in the U-M School of Public Health. "Population-based studies like the MECC study allow you to select patients and controls from the same general population," explains Niell. "Previ...Araucariaceae of New-Caledonia: endemic species in danger
...neous rocks (2) 39 million years B.P., molecular genetics investigations have not yet elucidated the origin and phylogeny of the different species. The Araucariaceae in New Caledonia are all trees. The Agathis species are voluminous trees developing some of the densest, most closed canopy of the forests. Ag...Story tips from the Department of Energys Oak Ridge National Laboratory, January 2004
...collaboration is a natural, says Dabney Johnson, a genetics researcher in ORNL's Life Sciences Division. "There are four or five host genes in mice that are known to have something to do with how susceptible mice are to anthrax," Johnson said. The plan is for Johnson and colleagues to make mutations that migh...Researchers find key gene in production of egg and sperm
...Robert Meeley of Pioneer Hi-Bred, who used reverse genetics technologies to identify additional phs1 mutants; Ljudmilla Timofejeva, a visiting scientist at UC Berkeley; and William Sheridan of the University of North Dakota. ...Scientists discover way to streamline analysis of maize genome
...ter in St. Louis, MO.; the University of Georgia's genetics department in Athens, GA; and Orion Genomics, in S...oped by researchers at the University of Georgia's genetics department, excludes highly-repetitive DNA sequences by using a different method that separates DNA ...WHAT: The confluence of advances in human genetics and reproductive science has resulted in the ability to perform genetic tests on embryos produced by in vitro fertilization. Embryos found to be free of a disease-causing gene mutation can then be selectively implanted into a woman's womb to initiat...Researchers look to stem cell therapy and bone marrow transplants to find a cure for diabetes
... a mystery to the medical community, although both genetics and environmental factors appear to play a role in the cause. Type 1 diabetes is usually diagnosed in children or young adults and, if not properly treated, can lead to complications such as heart and kidney disease, stroke, amputations, blindness, ...Changing one gene launches new fly species
...ce of a new species. "This study directly connects genetics with evolution," said Chung-I Wu, Ph.D., professor... flies have been a favorite model for the study of genetics since the early 20th century, recognition of consistent differences between tropical and temperate f...Easily paralyzed flies provide clues to neurodegeneration
...ies Drosophila melanogaster, a workhorse of modern genetics and molecular biology. But if you expose them to slightly elevated temperatures in the range of human body temperature, "in less than 10 seconds, some mutants are completely paralyzed. Others become totally incapacitated by convulsive seizures. It's ...Pittsburgh researchers engineer and successfully test SARS corona vaccine in animal model
...ab; Paul D. Robbins, Ph.D., professor of molecular genetics and biochemistry; Simon Barratt-Boyes, Ph.D., assistant professor in the department of infectious disease and microbiology at the University of Pittsburgh Graduate School of Public Health; and Adam Soloff, B.S., a GSPH student who works in Dr. Barrat...Growth hormone activates gene involved in healing damaged tissue
...ert Costa, professor of biochemistry and molecular genetics at the University of Illinois at Chicago and a member of the UIC Cancer Center. That discovery could help explain why we age. "Growth hormone levels decline as we grow older; as a result, the Foxm1b gene stops working and our bodies are less capable ...Chromosomes are 'nibbled' before they fuse, researchers report
...., professor and director of molecular biology and genetics at the Johns Hopkins School of Medicine. "Now it turns out that what we've always thought was the first step in the process is not the first step at all." Writing in the December issue of Molecular and Cellular Biology, Greider and Hopkins graduate...Gene may protect against heart disease rather than be harmful as previously thought
...t we will have a more complex understanding of the genetics involved that gives us new tools for treating hear...community with a non-human animal to study disease genetics in a controlled fashion that can render discoveries relevant for the human condition. Atherosclerosi...Circadian clock genes may provide targets for new cancer drugs
...mice. In the laboratory of the molecular and human genetics department at Baylor College of Medicine in Houston, Loning Fu, Ph.D., assistant professor, and her colleagues have shown that mice that lack this gene are prone to developing cancer. "Cancer cells and normal cells follow different circadian rhythm...Smallpox in Europe selected for genetic mutation that confers resistance to HIV infection
...es produce no CCR5 receptor. Based on a population genetics model, Galvani and Montgomery Slatkin, a UC Berkeley professor of integrative biology, argue that bubonic plague could not have caused such a rapid spread of this genetic mutation throughout Europe. Even though the Black Death pandemic killed off 25-...Advance in developing biological strategies to produce hydrogen and sequester carbon dioxide
...nome, as part of IBEA's efforts to use biology and genetics to reduce the amount of carbon dioxide released in...eland, vice president of research and professor of genetics at the University of Utah. DOE's Genomes to Life program aims to use the department's unique computa...Some re-established elk herds lack genetic diversity of ancestors
...ar Ecology, Rhodes and his colleagues compared the genetics of a reintroduced herd in Pennsylvania with the genetics of its source herds in Wyoming and South Dakota. Pennsylvania elk were hunted to extinction by the l...... this species of worm - long a workhorse of modern genetics and developmental biology - there are two sexes, m...ys Elizabeth B. Goodwin, a UW-Madison professor of genetics and the senior author of the Science article, " and C. elegans is poised beautifully to ask the qu...